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In this article, we focus on the analysis of the potential factors driving the spread of influenza, and possible policies to mitigate the adverse effects of the disease. To be precise, we first invoke discrete Fourier transform (DFT) to…

Machine Learning · Computer Science 2019-12-09 Ziming Liu , Yixuan Wang , Zizhao Han , Dian Wu

In this work we describe a non-parametric disease model that links the temporal change of the prevalence of an infectious disease to the incidence and the recovery rates. The model is only based on the common epidemiological measures…

Populations and Evolution · Quantitative Biology 2014-01-20 Ralph Brinks

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

The paradigm for compartment models in epidemiology assumes exponentially distributed incubation and removal times, which is not realistic in actual populations. Commonly used variations with multiple exponentially distributed variables are…

Populations and Evolution · Quantitative Biology 2021-02-10 P. Hernández , C. Pena , A. Ramos , J. J. Gómez-Cadenas

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Mathematical models of infectious diseases, which are in principle analytically tractable, use two general approaches. The first approach, generally known as compartmental modeling, addresses the time evolution of disease propagation at the…

Populations and Evolution · Quantitative Biology 2010-09-16 Pierre-André Noël , Bahman Davoudi , Robert C. Brunham , Louis J. Dubé , Babak Pourbohloul

We propose an integral model describing an epidemic of an infectious disease. The model is behavioural in the sense that the constitutive law for the force of infection includes a distributed delay, called "information index", that…

Dynamical Systems · Mathematics 2024-05-31 Bruno Buonomo , Eleonora Messina , Claudia Panico , Antonia Vecchio

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

Infectious diseases are caused by pathogenic microorganisms and can spread through different ways. Mathematical models and computational simulation have been used extensively to investigate the transmission and spread of infectious…

We introduce and analyze coupled, multi-strain epidemic models designed to simulate the emergence and dissemination of mutant (e.g. drug-resistant) pathogen strains. In particular, we investigate the mathematical and biological properties…

Populations and Evolution · Quantitative Biology 2017-05-10 Michael T. Meehan , Daniel G. Cocks , James M. Trauer , Emma S. McBryde

Despite the recent development of methods dealing with partially observed epidemic dynamics (unobserved model coordinates, discrete and noisy outbreak data), limitations remain in practice, mainly related to the quantity of augmented data…

Applications · Statistics 2021-07-26 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

The annual influenza outbreak leads to significant public health and economic burdens making it desirable to have prompt and accurate probabilistic forecasts of the disease spread. The United States Centers for Disease Control and…

Applications · Statistics 2025-08-29 Spencer Wadsworth , Jarad Niemi

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

Common respiratory viruses cause seasonal epidemics in sequential patterns. The underlying mechanisms for this pattern have been debated for some time. For influenza, contenders include temperature, humidity, and vitamin D levels. While…

Populations and Evolution · Quantitative Biology 2019-08-05 Gorm Gruner Jensen , Florian Uekermann , Kim Sneppen , Lone Simonsen

Mathematical models of epidemic dynamics offer significant insight into predicting and controlling infectious diseases. The dynamics of a disease model generally follow a susceptible, infected, and recovered (SIR) model, with some standard…

Populations and Evolution · Quantitative Biology 2013-11-28 Caitlyn Witkowski , Brian Blais

We develop a new structured compartmental model for the coevolutionary dynamics between susceptible and infectious individuals in heterogeneous SI epidemiological systems. In this model, the susceptible compartment is structured by a…

Populations and Evolution · Quantitative Biology 2024-10-10 Tommaso Lorenzi , Elisa Paparelli , Andrea Tosin

Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…

Applications · Statistics 2019-08-20 Md Mahsin , Rob Deardon , Patrick Brown

Epidemic models are useful tools in the fight against infectious diseases, as they allow policy makers to test and compare various strategies to limit disease transmission while mitigating collateral damage on the economy. Epidemic models…

Populations and Evolution · Quantitative Biology 2021-08-18 Joseph D. Peterson , Ronojoy Adhikari