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Partial Volume effects are present at the boundary between any two types of material in a CT image due to the scanner's Point Spread Function, finite voxel resolution, and importantly, the discrepancy in radiodensity between the two…
Automated Lymph Node (LN) detection is an important clinical diagnostic task but very challenging due to the low contrast of surrounding structures in Computed Tomography (CT) and to their varying sizes, poses, shapes and sparsely…
As lung cancer evolves, the presence of enlarged and potentially malignant lymph nodes must be assessed to properly estimate disease progression and select the best treatment strategy. Following the clinical guidelines, estimation of…
Utilizing computed tomography (CT) images to quickly estimate the severity of cases with COVID-19 is one of the most straightforward and efficacious methods. Two tasks were studied in this present paper. One was to segment the mask of…
The airflow in a subject-specific breathing human lung is simulated with a multiscale computational fluid dynamics (CFD) lung model. The three-dimensional (3D) airway geometry beginning from the mouth to about 7 generations of airways is…
We propose a novel procedure to improve liver and lesion segmentation from CT scans for U-Net based models. Our method extends standard segmentation pipelines to focus on higher target recall or reduction of noisy false-positive…
This paper newly introduces multi-modality loss function for GAN-based super-resolution that can maintain image structure and intensity on unpaired training dataset of clinical CT and micro CT volumes. Precise non-invasive diagnosis of lung…
Segmentation of the aorta is crucial for various medical analyses, such as the diagnosis and treatment of cardiovascular diseases. This work presents mathematical models and methods yielding a semi-automatic segmentation of the aorta from…
Multi-site structural MRI is increasingly used in neuroimaging studies to diversify subject cohorts. However, combining MR images acquired from various sites/centers may introduce site-related non-biological variations. Retrospective image…
CT image-guided thermal ablation is widely used for lung cancer treatment; however, follow-up data indicate that physicians' subjective assessments of intraoperative images often overestimate the ablation effect, potentially leading to…
High-resolution volumetric computed tomography (CT) is essential for accurate diagnosis and treatment planning in thoracic diseases; however, it is limited by radiation dose and hardware costs. We present the Transformer Volumetric…
Medical image registration is a critical task that estimates the spatial correspondence between pairs of images. However, current traditional and deep-learning-based methods rely on similarity measures to generate a deforming field, which…
Automatic segmentation of the liver and its lesion is an important step towards deriving quantitative biomarkers for accurate clinical diagnosis and computer-aided decision support systems. This paper presents a method to automatically…
Normal Pressure Hydrocephalus (NPH) is one of the few reversible forms of dementia, Due to their low cost and versatility, Computed Tomography (CT) scans have long been used as an aid to help diagnose intracerebral anomalies such as NPH.…
Large-volume optical coherence tomography (OCT)-setups employ scanning mirrors and suffer from non-linear geometric distortion artifacts in which the degree of distortion is determined by the maximum angles over which the mirrors rotate. In…
Reliable and automatic segmentation of lung lobes is important for diagnosis, assessment, and quantification of pulmonary diseases. The existing techniques are prohibitively slow, undesirably rely on prior (airway/vessel) segmentation,…
We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and…
Background: Pleural Effusions (PE) is a common finding in many different clinical conditions, but accurately measuring their volume from CT scans is challenging. Purpose: To improve PE segmentation and quantification for enhanced clinical…
The novel Coronavirus disease (COVID-19) is a highly contagious virus and has spread all over the world, posing an extremely serious threat to all countries. Automatic lung infection segmentation from computed tomography (CT) plays an…
Semantic segmentation is a crucial task in medical image processing, essential for segmenting organs or lesions such as tumors. In this study we aim to improve automated segmentation in CBCTs through multi-task learning. To evaluate effects…