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Related papers: Deep learning for extracting protein-protein inter…

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Motivation: High-throughput experimental techniques have been producing more and more protein-protein interaction (PPI) data. PPI network alignment greatly benefits the understanding of evolutionary relationship among species, helps…

Data Structures and Algorithms · Computer Science 2016-04-13 Somaye Hashemifar , Qixing Huang , Jinbo XU

Mechanistic interpretability is concerned with analyzing individual components in a (convolutional) neural network (CNN) and how they form larger circuits representing decision mechanisms. These investigations are challenging since CNNs…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Robin Hesse , Jonas Fischer , Simone Schaub-Meyer , Stefan Roth

This paper proposes a tree-based convolutional neural network (TBCNN) for discriminative sentence modeling. Our models leverage either constituency trees or dependency trees of sentences. The tree-based convolution process extracts…

Computation and Language · Computer Science 2015-06-03 Lili Mou , Hao Peng , Ge Li , Yan Xu , Lu Zhang , Zhi Jin

We propose a novel deep convolutional neural network (CNN) based multi-task learning approach for open-set visual recognition. We combine a classifier network and a decoder network with a shared feature extractor network within a multi-task…

Computer Vision and Pattern Recognition · Computer Science 2019-03-11 Poojan Oza , Vishal M. Patel

Numerous cellular functions rely on protein$\unicode{x2013}$protein interactions. Efforts to comprehensively characterize them remain challenged however by the diversity of molecular recognition mechanisms employed within the proteome. Deep…

Biomolecules · Quantitative Biology 2023-12-08 Julia R. Rogers , Gergő Nikolényi , Mohammed AlQuraishi

Features play a crucial role in computer vision. Initially designed to detect salient elements by means of handcrafted algorithms, features are now often learned by different layers in Convolutional Neural Networks (CNNs). This paper…

Computer Vision and Pattern Recognition · Computer Science 2021-11-18 Loris Nanni , Stefano Ghidoni , Sheryl Brahnam

Since the BOSS competition, in 2010, most steganalysis approaches use a learning methodology involving two steps: feature extraction, such as the Rich Models (RM), for the image representation, and use of the Ensemble Classifier (EC) for…

Multimedia · Computer Science 2018-01-15 Lionel Pibre , Pasquet Jérôme , Dino Ienco , Marc Chaumont

Recurrent Neural Networks (RNNs) have been widely used in processing natural language tasks and achieve huge success. Traditional RNNs usually treat each token in a sentence uniformly and equally. However, this may miss the rich semantic…

Computation and Language · Computer Science 2018-11-14 Chang Xu , Weiran Huang , Hongwei Wang , Gang Wang , Tie-Yan Liu

Click-Through Rate prediction is an important task in recommender systems, which aims to estimate the probability of a user to click on a given item. Recently, many deep models have been proposed to learn low-order and high-order feature…

Information Retrieval · Computer Science 2019-04-30 Bin Liu , Ruiming Tang , Yingzhi Chen , Jinkai Yu , Huifeng Guo , Yuzhou Zhang

Polyphenols and proteins are essential biomolecules that influence food functionality and, by extension, human health. Their interactions -- hereafter referred to as PhPIs (polyphenol-protein interactions) -- affect key processes such as…

Biomolecules · Quantitative Biology 2025-08-06 Qiang Liu , Tiantian Wang , Binbin Nian , Feiyang Ma , Siqi Zhao , Andrés F. Vásquez , Liping Guo , Chao Ding , Mehdi D. Davari

Deep convolutional neural network has made huge revolution and shown its superior performance on computer vision tasks such as classification and segmentation. Recent years, researches devote much effort to scaling down size of network…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Yingdong Hu

The worldwide surge of multiresistant microbial strains has propelled the search for alternative treatment options. The study of Protein-Protein Interactions (PPIs) has been a cornerstone in the clarification of complex physiological and…

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

Quantitative Methods · Quantitative Biology 2022-07-15 Aaron Wang

Convolutional Neural Networks (CNNs) achieve high performance in image classification tasks but are challenging to deploy on resource-limited hardware due to their large model sizes. To address this issue, we leverage Mutual Information, a…

Machine Learning · Computer Science 2024-11-28 Tien Vu-Van , Dat Du Thanh , Nguyen Ho , Mai Vu

A multi-modal emotion recognition method was established by combining two-channel convolutional neural network with ring network. This method can extract emotional information effectively and improve learning efficiency. The words were…

Artificial Intelligence · Computer Science 2023-11-21 Jiazhen Wang

Protein-Protein Interactions (PPIs) are fundamental in various biological processes and play a key role in life activities. The growing demand and cost of experimental PPI assays require computational methods for efficient PPI prediction.…

Machine Learning · Computer Science 2024-02-23 Lirong Wu , Yijun Tian , Yufei Huang , Siyuan Li , Haitao Lin , Nitesh V Chawla , Stan Z. Li

Drug-drug interaction (DDI) is a vital information when physicians and pharmacists intend to co-administer two or more drugs. Thus, several DDI databases are constructed to avoid mistakenly combined use. In recent years, automatically…

Computation and Language · Computer Science 2017-05-19 Zibo Yi , Shasha Li , Jie Yu , Qingbo Wu

A key component of deep learning (DL) for natural language processing (NLP) is word embeddings. Word embeddings that effectively capture the meaning and context of the word that they represent can significantly improve the performance of…

In recent years, deep learning techniques have made significant strides in molecular generation for specific targets, driving advancements in drug discovery. However, existing molecular generation methods present significant limitations:…

Machine Learning · Computer Science 2025-03-12 Taojie Kuang , Qianli Ma , Athanasios V. Vasilakos , Yu Wang , Qiang , Cheng , Zhixiang Ren