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Biological networks have arisen as an attractive paradigm of genomic science ever since the introduction of large scale genomic technologies which carried the promise of elucidating the relationship in functional genomics. Microarray…

Applications · Statistics 2013-08-20 Anani Lotsi , Ernst Wit

Network structures in various backgrounds play important roles in social, technological, and biological systems. However, the observable network structures in real cases are often incomplete or unavailable due to measurement errors or…

Machine Learning · Computer Science 2020-01-22 Mengyuan Chen , Jiang Zhang , Zhang Zhang , Lun Du , Qiao Hu , Shuo Wang , Jiaqi Zhu

Gene expression is a readily-observed quantification of transcriptional activity and cellular state that enables the recovery of the relationships between regulators and their target genes. Reconstructing transcriptional regulatory networks…

Molecular Networks · Quantitative Biology 2016-09-22 Anthony Gitter , Furong Huang , Ragupathyraj Valluvan , Ernest Fraenkel , Animashree Anandkumar

Network representation learning, as an approach to learn low dimensional representations of vertices, has attracted considerable research attention recently. It has been proven extremely useful in many machine learning tasks over large…

Machine Learning · Computer Science 2019-06-11 Hao Peng , Jianxin Li , Hao Yan , Qiran Gong , Senzhang Wang , Lin Liu , Lihong Wang , Xiang Ren

We present a graph-based semi-supervised learning (SSL) method for learning edge flows defined on a graph. Specifically, given flow measurements on a subset of edges, we want to predict the flows on the remaining edges. To this end, we…

Machine Learning · Computer Science 2019-05-21 Junteng Jia , Michael T. Schaub , Santiago Segarra , Austin R. Benson

Supervised learning problems with side information in the form of a network arise frequently in applications in genomics, proteomics and neuroscience. For example, in genetic applications, the network side information can accurately capture…

Statistics Theory · Mathematics 2024-10-24 Sagnik Nandy , Subhabrata Sen

This work proposes a novel method for semi-supervised learning from partially labeled massive network-structured datasets, i.e., big data over networks. We model the underlying hypothesis, which relates data points to labels, as a graph…

Machine Learning · Computer Science 2017-05-16 Alexander Jung , Alfred O. Hero , Alexandru Mara , Saeed Jahromi

We study the challenges of applying deep learning to gene expression data. We find experimentally that there exists non-linear signal in the data, however is it not discovered automatically given the noise and low numbers of samples used in…

Genomics · Quantitative Biology 2018-06-20 Francis Dutil , Joseph Paul Cohen , Martin Weiss , Georgy Derevyanko , Yoshua Bengio

Modern deep learning models in computer vision require large datasets of real images, which are difficult to curate and pose privacy and legal concerns, limiting their commercial use. Recent works suggest synthetic data as an alternative,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Farnood Salehi , Vandit Sharma , Amirhossein Askari Farsangi , Tunç Ozan Aydın

In a recent paper by Kurasov, L\"uck, Mugnolo and Wolf, a hybrid gene regulatory network was proposed to model gene expression dynamics by using a stochastic system of coupled partial differential equations. This approach approximates…

Functional Analysis · Mathematics 2024-06-28 Alexander Dobrick , Julian Hölz

Image reconstruction from undersampled k-space data plays an important role in accelerating the acquisition of MR data, and a lot of deep learning-based methods have been exploited recently. Despite the achieved inspiring results, the…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Chen Hu , Cheng Li , Haifeng Wang , Qiegen Liu , Hairong Zheng , Shanshan Wang

Constructing gene interaction networks (GINs) from high-throughput gene expression data is an important and challenging problem in systems biology. Existing algorithms produce networks that either have undirected and unweighted edges, or…

Genomics · Quantitative Biology 2016-03-15 Nitin Kumar Singh , M. Eren Ahsen , Shiva Mankala , Hyun-Seok Kim , Michael A. White , M. Vidyasagar

The reliance of organisations on computer networks is enabled by network programmability, which is typically achieved through Service Function Chaining. These chains virtualise network functions, link them, and programmatically embed them…

Neural and Evolutionary Computing · Computer Science 2025-12-11 Theviyanthan Krishnamohan , Lauritz Thamsen , Paul Harvey

We propose a scalable method for semi-supervised (transductive) learning from massive network-structured datasets. Our approach to semi-supervised learning is based on representing the underlying hypothesis as a graph signal with small…

Machine Learning · Computer Science 2016-11-03 Alexander Jung , Alfred O. Hero , Alexandru Mara , Sabeur Aridhi

Motivation: Measurements of gene expression over time enable the reconstruction of transcriptional networks. However, Bayesian networks and many other current reconstruction methods rely on assumptions that conflict with the differential…

Molecular Networks · Quantitative Biology 2009-07-02 D. R. Bickel , Z. Montazeri , P. -C. Hsieh , M. Beatty , S. J. Lawit , N. J. Bate

Recent developments in computers and automated data collection strategies have greatly increased the interest in statistical modeling of dynamic networks. Many of the statistical models employed for inference on large-scale dynamic networks…

Computation · Statistics 2018-07-25 Abhirup Mallik , Zack W. Almquist

Inferring gene regulatory networks is an important problem in systems biology. However, these networks can be hard to infer from experimental data because of the inherent variability in biological data as well as the large number of genes…

Applications · Statistics 2016-03-16 William Chad Young , Ka Yee Yeung , Adrian E. Raftery

Deep neural networks have been widely used in communication signal recognition and achieved remarkable performance, but this superiority typically depends on using massive examples for supervised learning, whereas training a deep neural…

Signal Processing · Electrical Eng. & Systems 2023-11-15 Weidong Wang , Hongshu Liao , Lu Gan

Graph convolutional neural networks~(GCNs) have recently demonstrated promising results on graph-based semi-supervised classification, but little work has been done to explore their theoretical properties. Recently, several deep neural…

Machine Learning · Computer Science 2020-02-28 Jilin Hu , Jianbing Shen , Bin Yang , Ling Shao

We apply network Lasso to semi-supervised regression problems involving network structured data. This approach lends quite naturally to highly scalable learning algorithms in the form of message passing over an empirical graph which…

Machine Learning · Statistics 2018-12-31 A. Jung , N. Vesselinova