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Receptor occupancy (RO) studies using PET neuroimaging play a critical role in the development of drugs targeting the central nervous system (CNS). The conventional approach to estimate drug receptor occupancy consists in estimation of…
The segmentation of the breast from the chest wall is an important first step in the analysis of breast magnetic resonance images. 3D U-nets have been shown to obtain high segmentation accuracy and appear to generalize well when trained on…
Deep learning (DL)-based image reconstruction methods for photoacoustic computed tomography (PACT) have developed rapidly in recent years. However, most existing methods have not employed standardized datasets, and their evaluations rely on…
The importance of regularization has been well established in image reconstruction -- which is the computational inversion of imaging forward model -- with applications including deconvolution for microscopy, tomographic reconstruction,…
Despite advances in deep learning, robustness under domain shift remains a major bottleneck in medical imaging settings. Findings on natural images suggest that deep neural models can show a strong textural bias when carrying out image…
Whole-brain proton magnetic resonance spectroscopic imaging (1H-MRSI) is a non-invasive technique for assessing neurochemical distribution in the brain, offering valuable insights into brain functions and neural diseases. It greatly…
In Magnetic Resonance Imaging (MRI) data samples are collected in the spatial frequency domain (k-space), typically by time-consuming line-by-line scanning on a Cartesian grid. Scans can be accelerated by simultaneous acquisition of data…
Purpose/Objective: Brain tumors result in 20 years of lost life on average. Standard therapies induce complex structural changes in the brain that are monitored through MRI. Recent developments in artificial intelligence (AI) enable…
The information regarding how the intergalactic medium is reionized by astrophysical sources is contained in the tomographic three-dimensional 21 cm images from the epoch of reionization. In Zhao et al. (2022a) ("Paper I"), we demonstrated…
This study compares two statistical approaches to image reconstruction in single-photon emission computed tomography (SPECT). We evaluated the widely used Ordered Subset Expectation Maximization (OSEM) algorithm and the newer Maximum a…
Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence…
This retrospective-prospective study evaluated whether a deep learning-based MRI reconstruction algorithm can preserve diagnostic quality in brain MRI scans accelerated up to fourfold, using both public and prospective clinical data. The…
Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…
Purpose: To assess whether breast lesion segmentation can be learned directly from acquired MRI k-space, and whether doing so improves robustness when data are accelerated or noisy. Materials and Methods: This retrospective study used…
Digital Breast Tomosynthesis (DBT) enhances finding visibility for breast cancer detection by providing volumetric information that reduces the impact of overlapping tissues; however, limited annotated data has constrained the development…
With the rapid proliferation of 3D devices and the shortage of 3D content, stereo conversion is attracting increasing attention. Recent works introduce pretrained Diffusion Models (DMs) into this task. However, due to the scarcity of…
Recently, social infrastructure is aging, and its predictive maintenance has become important issue. To monitor the state of infrastructures, bridge inspection is performed by human eye or bay drone. For diagnosis, primary damage region are…
Robust regression techniques rely on least-squares optimization, which works well for Gaussian noise but fails in the presence of asymmetric structured noise. We propose a hybrid neural-symbolic architecture where a transformer encoder…
We use the replica method of statistical mechanics to examine a typical performance of correctly reconstructing $N$-dimensional sparse vector $bx=(x_i)$ from its linear transformation $by=bF bx$ of $P$ dimensions on the basis of…
Purpose: This study presents a variable resolution (VR) sampling and deep learning reconstruction approach for multi-spectral MRI near metal implants, aiming to reduce scan times while maintaining image quality. Background: The rising use…