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Purpose: Many useful image quality metrics for evaluating linear image reconstruction techniques do not apply to or are difficult to interpret for non-linear image reconstruction. The vast majority of metrics employed for evaluating…
Fiber-like features are an important aspect of breast imaging. Vessels and ducts are present in all breast images, and spiculations radiating from a mass can indicate malignancy. Accordingly, fiber objects are one of the three types of…
Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…
PURPOSE: We develop a practical, iterative algorithm for image-reconstruction in under-sampled tomographic systems, such as digital breast tomosynthesis (DBT). METHOD: The algorithm controls image regularity by minimizing the image total…
Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…
The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…
Purpose: The goal of this study is to develop a novel deep learning (DL) based reconstruction framework to improve the digital breast tomosynthesis (DBT) imaging performance. Methods: In this work, the DIR-DBTnet is developed for DBT image…
Purpose: Digital phantoms are one of the key components of virtual imaging trials (VITs) that aim to assess and optimize new medical imaging systems and algorithms. However, these phantoms vary in their voxel resolution, appearance, and…
Recent research has explored using neural networks to reconstruct undersampled magnetic resonance imaging (MRI) data. Because of the complexity of the artifacts in the reconstructed images, there is a need to develop task-based approaches…
Advances in instrumentation and computation have enabled increasingly sophisticated tomographic reconstruction methods. However, existing evaluation practices -- often based on simple phantoms and global image metrics -- are limited in…
Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…
To reduce scanning time and/or improve spatial/temporal resolution in some MRI applications, parallel MRI (pMRI) acquisition techniques with multiple coils acquisition have emerged since the early 1990s as powerful 3D imaging methods that…
The goal of this thesis is to provide a framework for the use of task-based metrics of image quality to aid in the design, implementation, and evaluation of CT image reconstruction algorithms and CT systems in general. We support the view…
Foundation models have shown promise in medical imaging but remain underexplored for three-dimensional imaging modalities. No foundation model currently exists for Digital Breast Tomosynthesis (DBT), despite its use for breast cancer…
Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…
We aim to investigate the impact of image and signal properties on visual attention mechanisms during a signal detection task in digital images. The application of insight yielded from this work spans many areas of digital imaging where…
There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Cooper's ligaments, blood vessels, and spiculated lesions. Such structures…
In this study we evaluated the task-based image quality of a low contrast clinical task for the abdomen protocol (e.g., pancreatic tumour) of three different CT vendors, exploiting three model-based iterative reconstruction (MBIR) levels.…
Objective: To develop an automatic image normalization algorithm for intensity correction of images from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) acquired by different MRI scanners with various imaging…
Digital breast tomosynthesis is rapidly replacing digital mammography as the basic x-ray technique for evaluation of the breasts. However, the sparse sampling and limited angular range gives rise to different artifacts, which manufacturers…