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The organization of live cells into tissues and their subsequent biological function involves inter-cell mechanical interactions, which are mediated by their elastic environment. To model this interaction, we consider cells as spherical…

Soft Condensed Matter · Physics 2024-02-20 Roman Golkov , Yair Shokef

An electronic diode is a nonlinear semiconductor circuit component that allows conduction of electrical current in one direction only. A component with similar functionality for electromagnetic waves, an electromagnetic isolator, is based…

We propose a mechanism for mechanical regulation at the membrane of living cells, based on the exchange of membrane area between the cell membrane and a membrane reservoir. The reservoir is composed of invaginated membrane microdomains…

Subcellular Processes · Quantitative Biology 2007-05-23 Pierre Sens , Matthew S. Turner

Living tissues experience various external forces on cells, influencing their behaviour, physiology, shape, gene expression, and destiny through interactions with their environment. Despite much research done in this area, challenges remain…

Quantitative Methods · Quantitative Biology 2024-03-05 Akepogu Venkateshwarlu , Akshayveer , Sundeep Singh , Roderick Melnik

The shapes of epithelial tissues result from a complex interplay of contractile forces in the cytoskeleta of the cells in the tissue, and adhesion forces between them. A host of discrete, cell-based models describe these forces by assigning…

Soft Condensed Matter · Physics 2019-02-27 Pierra A. Haas , Raymond E. Goldstein

A novel concept for the design of nonlinear optical diodes is proposed which uses the multistability of coupled nonlinear microcavities and the dependence of switching thresholds on the direction of incidence. A typical example of such…

Optics · Physics 2011-05-31 Victor Grigoriev , Fabio Biancalana

A design of all optical diode in $L$-shaped photonic crystal waveguide is proposed that uses the multistability of single nonlinear Kerr microcavity with two dipole modes. Asymmetry of the waveguide is achieved by difference in coupling of…

Optics · Physics 2014-04-17 E. N. Bulgakov , A. F. Sadreev

Excitable membranes are an important type of nonlinear dynamical system and their study can be used to provide a connection between physical and biological circuits. We discuss two models of excitable membranes important in cardiac and…

Biological Physics · Physics 2012-12-18 Jarrett L. Lancaster , Esther M. Leise , Edward H. Hellen

We study the dynamics of a thick polar epithelium subjected to the action of both an electric and a flow field in a planar geometry. We develop a generalized continuum hydrodynamic description and describe the tissue as a two component…

Cell Behavior · Quantitative Biology 2018-11-12 Niladri Sarkar , Jacques Prost , Frank Jülicher

The rising demand for high-performing batteries requires new technological concepts. To facilitate fast charge and discharge, hierarchically structured electrodes offer short diffusion paths in the active material. However, there are still…

Elastic active matter or active solid consists of self-propelled units embedded in an elastic matrix. Active solid resists deformation; the shape-preserving property and the intrinsic non-equilibrium nature make active solids a superior…

Soft Condensed Matter · Physics 2023-02-01 Haoran Xu , Yulu Huang , Rui Zhang , Yilin Wu

A novel Y-shaped membraneless flow-through electrolyzer is introduced to achieve a homogeneous electrochemical reaction across the entire electrode in a cost-efficient cell design with effective product separation. Numerical simulations of…

We introduce the notion of cell division-induced activity and show that the cell division generates extensile forces and drives dynamical patterns in cell assemblies. Extending the hydrodynamic models of lyotropic active nematics we…

Soft Condensed Matter · Physics 2015-08-07 Amin Doostmohammadi , Sumesh P. Thampi , Thuan B. Saw , Chwee T. Lim , Benoit Ladoux , Julia M. Yeomans

Emergent nonreciprocity in active matter drives the formation of self-organized states that transcend the behaviors of equilibrium systems. Integrating experiments, theory and simulations, we demonstrate that active solids composed of…

Engineering simple, artificial models of living cells allows synthetic biologists to study cellular functions under well-controlled conditions. Reconstituting multicellular behaviors with synthetic cell-mimics is still a challenge because…

Biomolecules · Quantitative Biology 2021-04-29 Imre Banlaki , Francois-Xavier Lehr , Henrike Niederholtmeyer

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

Adaptation and Self-Organizing Systems · Physics 2022-02-01 Ria Ghosh , Shakti N. Menon

Undoped and strongly photoexcited semiconductor superlattices with field-dependent recombination behave as excitable or oscillatory media with spatially discrete nonlinear convection and diffusion. Infinitely long, dc-current-biased…

Mesoscale and Nanoscale Physics · Physics 2015-05-30 J. I. Arana , L. L. Bonilla , H. T. Grahn

Excitability is an attribute of life, and is a driving force in the descent of complexity. Cellular electrical activity as realized by membrane proteins that act as either channels or transporters is the basis of excitability. Electrical…

Biomolecules · Quantitative Biology 2009-11-05 Ashok Palaniappan , Eric Jakobsson

We study synchronization of two cardiomyocytes mediated by elastic interactions through the substrate. Modeling each cell as an oscillating force dipole governed by a Rayleigh-type equation, we derive an effective mechanical coupling from…

Soft Condensed Matter · Physics 2026-05-15 Akinari Tomiie , Nariya Uchida

Liposome vesicles tend to align with an applied magnetic field. This is due to the directional magnetic susceptibility difference of the lipids which form the membrane of these vesicles. In this work a model of liposome vesicles exposed to…

Soft Condensed Matter · Physics 2016-08-22 David Salac