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We consider a generic class of gene circuits affected by nonlinear extrinsic noise. To address this nonlinearity we introduce a general perturbative methodology based on assuming timescale separation between noise and genes dynamics, with…

Molecular Networks · Quantitative Biology 2023-05-10 Gerardo Aquino , Andrea Rocco

The noise can stabilize a fluctuating or a periodically driven metastable state in such a way that the system remains in this state for a longer time than in the absence of white noise. This is the noise enhanced stability phenomenon,…

Statistical Mechanics · Physics 2007-05-23 Bernardo Spagnolo , Nikolay V. Agudov , Alexander A. Dubkov

We consider the coaction of two distinct noise sources on the activation process of a single and two interacting excitable units, which are mathematically described by the Fitzhugh-Nagumo equations. We determine the most probable activation…

Chaotic Dynamics · Physics 2016-04-19 Igor Franović , Kristina Todorović , Matjaz Perc , Nebojša Vasović , Nikola Burić

We consider a model of active Brownian agents interacting via a harmonic attractive potential in a two-dimensional system in the presence of noise. By numerical simulations, we show that this model possesses a noise-induced transition…

Biological Physics · Physics 2007-05-23 Udo Erdmann , Werner Ebeling , Alexander S. Mikhailov

Here we numerically study a model of excitable media, namely, a network with occasionally quiet nodes and connection weights that vary with activity on a short-time scale. Even in the absence of stimuli, this exhibits unstable dynamics,…

Disordered Systems and Neural Networks · Physics 2015-05-19 S. de Franciscis , J. J. Torres , J. Marro

This study investigates the influence of initial conditions on the evolution and properties of linear quasi-normal modes (QNMs). Using a toy model in which the quasi-normal mode can be unambiguously identified, we highlight an aspect of…

General Relativity and Quantum Cosmology · Physics 2024-12-05 Ameya Chavda , Macarena Lagos , Lam Hui

Slow oscillations are electrical potential oscillations with a spectral peak frequency of $\sim$0.8 Hz, and hallmark the electroencephalogram during slow-wave sleep. Recent studies have indicated a causal contribution of slow oscillations…

Neurons and Cognition · Quantitative Biology 2014-07-31 Hong-Viet V. Ngo , Jens Christian Claussen , Jan Born , Matthias Mölle

We analyze a piecewise-linear FitzHugh-Nagumo model. The system exhibits a canard near which both small amplitude and large amplitude periodic orbits exist. The addition of small noise induces mixed-mode oscillations (MMOs) in the vicinity…

Dynamical Systems · Mathematics 2015-05-20 David J. W. Simpson , Rachel Kuske

We describe general characteristics of the Hodgkin-Huxley neuron's response to a periodic train of short current pulses with Gaussian noise. The deterministic neuron is bistable for antiresonant frequencies. When the stimuli arrive at the…

Biological Physics · Physics 2015-03-17 L. S. Borkowski

In the cerebral cortex, neurons are subject to a continuous bombardment of synaptic inputs originating from the network's background activity. This leads to ongoing, mostly subthreshold membrane dynamics that depends on the statistics of…

Biological Physics · Physics 2009-11-07 Ulrich Hillenbrand

First passage time experiments were used to explore the effects of low amplitude noise as a source of accelerated phase space diffusion in two-dimensional Hamiltonian systems, and these effects were then compared with the effects of…

Astrophysics · Physics 2009-10-31 Ilya V. Pogorelov , Henry E. Kandrup

We investigate the modes of oscillation of heterogeneous ring-networks of quadratic integrate-and-fire neurons with non-local, space-dependent coupling. Perturbations of the equilibrium state with a particular wave number produce transient…

Neurons and Cognition · Quantitative Biology 2017-11-15 Jose M. Esnaola-Acebes , Alex Roxin , Daniele Avitabile , Ernest Montbrió

A bifurcating system subject to multiplicative noise can display on-off intermittency. Using a canonical example, we investigate the extreme sensitivity of the intermittent behavior to the nature of the noise. Through a perturbative…

Statistical Mechanics · Physics 2009-11-11 Sebastien Aumaitre , Francois Petrelis , Kirone Mallick

Neurons are the central biological objects in understanding how the brain works. The famous Hodgkin-Huxley model, which describes how action potentials of a neuron are initiated and propagated, consists of four coupled nonlinear…

Neurons and Cognition · Quantitative Biology 2010-02-01 William Hanan , Dhagash Mehta , Guillaume Moroz , Sepanda Pouryahya

Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

Neurons and Cognition · Quantitative Biology 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Noise plays a fundamental role in a wide variety of physical and biological dynamical systems. It can arise from an external forcing or due to random dynamics internal to the system. It is well established that even weak noise can result in…

Analysis of PDEs · Mathematics 2019-08-06 Eric Forgoston , Richard O. Moore

Neural oscillations are universal phenomena and can be observed at different levels of neural systems, from single neuron to macroscopic brain. The frequency of those oscillations are related to the brain functions. However, little is know…

Neurons and Cognition · Quantitative Biology 2015-07-30 Lianchun Yu , Longfei Wang , Fei Jia , Duojie Jia

We derive the exact bifurcation diagram of the Duffing oscillator with parametric noise thanks to the analytical study of the associated Lyapunov exponent. When the fixed point is unstable for the underlying deterministic dynamics, we show…

Statistical Mechanics · Physics 2009-11-10 Kirone Mallick , Philippe Marcq

We provide a simple framework for the study of parametric (multiplicative) noise, making use of scale parameters. We show that for a large class of stochastic differential equations increasing the multiplicative noise intensity surprisingly…

Statistical Mechanics · Physics 2024-11-22 Ewan T. Phillips , Benjamin Lindner , Holger Kantz

We consider the long-time dynamics of a general class of nonlinear Fokker-Planck equations, describing the large population behavior of mean-field interacting units. The main motivation of this work concerns the case where the individual…

Analysis of PDEs · Mathematics 2020-01-08 Eric Lucon , Christophe Poquet