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Background: Recent studies have shown a decrease in annualised relapse rates (ARRs) in placebo groups of randomised controlled trials (RCTs) in relapsing multiple sclerosis (RMS). Methods: We conducted a systematic literature search of RCTs…

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

Image signals typically are defined on a rectangular two-dimensional grid. However, there exist scenarios where this is not fulfilled and where the image information only is available for a non-regular subset of pixel position. For…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jürgen Seiler , André Kaup

Parallel imaging is widely used in magnetic resonance imaging as an acceleration technology. Traditional linear reconstruction methods in parallel imaging often suffer from noise amplification. Recently, a non-linear robust…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Hui Tao , Haifeng Wang , Shanshan Wang , Dong Liang , Xiaoling Xu , Qiegen Liu

High-resolution (HR) quantitative MRI (qMRI) relaxometry provides objective tissue characterization but remains clinically underutilized due to lengthy acquisition times. We propose a physics-informed, self-supervised framework for qMRI…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Alireza Samadifardheris , Dirk H. J. Poot , Florian Wiesinger , Stefan Klein , Juan A. Hernandez-Tamames

This paper focuses on the analysis of sequential image data, particularly brain imaging data such as MRI, fMRI, CT, with the motivation of understanding the brain aging process and neurodegenerative diseases. To achieve this goal, we…

Machine Learning · Statistics 2024-07-22 Zhenghao Li , Sanyou Wu , Long Feng

Magnetic resonance imaging (MRI) is indispensable for diagnosing and planning treatment in various medical conditions due to its ability to produce multi-series images that reveal different tissue characteristics. However, integrating these…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Churan Wang , Fei Gao , Lijun Yan , Siwen Wang , Yizhou Yu , Yizhou Wang

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

Over the brief time intervals available for processing retinal output, roughly 50 to 300 msec, the number of extra spikes generated by individual ganglion cells can be quite variable. Here, computer-generated spike trains were used to…

Neurons and Cognition · Quantitative Biology 2007-09-14 Garrett T. Kenyon

Aggregating multi-site brain MRI data can enhance deep learning model training, but also introduces non-biological heterogeneity caused by site-specific variations (e.g., differences in scanner vendors, acquisition parameters, and imaging…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mengqi Wu , Yongheng Sun , Qianqian Wang , Pew-Thian Yap , Mingxia Liu

Mixed model repeated measures (MMRM) is the most common analysis approach used in clinical trials for Alzheimer's disease and other progressive diseases measured with continuous outcomes measured over time. The model treats time as a…

Single-channel speech enhancement approaches do not always improve automatic recognition rates in the presence of noise, because they can introduce distortions unhelpful for recognition. Following a trend towards end-to-end training of…

Sound · Computer Science 2021-12-14 Peter Plantinga , Deblin Bagchi , Eric Fosler-Lussier

Synthetic aperture radar automatic target recognition (SAR ATR) with limited data has recently been a hot research topic to enhance weak generalization. Despite many excellent methods being proposed, a fundamental theory is lacked to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Chenwei Wang , You Qin , Li Li , Siyi Luo , Yulin Huang , Jifang Pei , Yin Zhang , Jianyu Yang

Purpose: Visualization of subcortical gray matter is essential in neuroscience and clinical practice, particularly for disease understanding and surgical planning.While multi-inversion time (multi-TI) T$_1$-weighted (T$_1$-w) magnetic…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Savannah P. Hays , Lianrui Zuo , Anqi Feng , Yihao Liu , Blake E. Dewey , Jiachen Zhuo , Ellen M. Mowry , Scott D. Newsome , Jerry L. Prince , Aaron Carass

Neural correlations play a critical role in sensory information coding. They are of two kinds: signal correlations, when neurons have overlapping sensitivities, and noise correlations from network effects and shared noise. In experiments…

Neurons and Cognition · Quantitative Biology 2025-07-03 Gabriel Mahuas , Thomas Buffet , Olivier Marre , Ulisse Ferrari , Thierry Mora

The impact of in-scanner motion on functional magnetic resonance imaging (fMRI) data has a notorious reputation in the neuroimaging community. State-ofthe-art guidelines advise to scrub out excessively corrupted frames as assessed by a…

Neurons and Cognition · Quantitative Biology 2019-06-18 Thomas A. W. Bolton , Daniela Zöller , César Caballero-Gaudes , Valeria Kebets , Enrico Glerean , Dimitri Van De Ville

When modelling time series, it is common to decompose observed variation into a "signal" process, the process of interest, and "noise", representing nuisance factors that obfuscate the signal. To separate signal from noise, assumptions must…

Methodology · Statistics 2020-11-11 Richard Creswell , Ben Lambert , Chon Lok Lei , Martin Robinson , David Gavaghan

The analysis of the system behavior under the effect of the additive noises has been done using a simple model of shear melting. The situation with low intensity of the order parameter noise has been investigated in detail, and time…

Statistical Mechanics · Physics 2014-07-09 Iakov A. Lyashenko , Vadym N. Borysiuk , Nataliia N. Manko

We derive general equations for non-linearity corrections and statistical uncertainty (variance) estimates for data acquired with near-infrared detectors employing correlated double sampling, multiple correlated double sampling (Fowler…

Astrophysics · Physics 2009-11-10 W. D. Vacca , M. C. Cushing , J. T. Rayner

Neuroimaging-based prediction methods for intelligence and cognitive abilities have seen a rapid development in literature. Among different neuroimaging modalities, prediction based on functional connectivity (FC) has shown great promise.…

Neurons and Cognition · Quantitative Biology 2023-07-20 Yang Li , Xin Ma , Raj Sunderraman , Shihao Ji , Suprateek Kundu