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Nanoparticles (NPs) have proven their applicability in biosensing, drug delivery, and photo-thermal therapy, but their performance depends critically on the distribution and number of functional groups on their surface. When studying…

The point spread function (PSF) serves as a fundamental descriptor linking the real-world scene to the captured signal, manifesting as camera blur. Accurate PSF estimation is crucial for both optical characterization and computational…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Jiajian He , Enjie Hu , Shiqi Chen , Tianchen Qiu , Huajun Feng , Zhihai Xu , Yueting Chen

Accurate blur estimation is essential for high-performance imaging across various applications. Blur is typically represented by the point spread function (PSF). In this paper, we propose a physics-informed PSF learning framework for…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Liqun Chen , Yuxuan Li , Jun Dai , Jinwei Gu , Tianfan Xue

We present a new algorithm for estimating the Point Spread Function (PSF) in wide-field astronomical images with extreme source crowding. Robust and accurate PSF estimation in crowded astronomical images dramatically improves the fidelity…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Brendt Wohlberg , Przemek Wozniak

Diffusion probabilistic models have been recently used in a variety of tasks, including speech enhancement and synthesis. As a generative approach, diffusion models have been shown to be especially suitable for imputation problems, where…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-05 Tal Peer , Simon Welker , Timo Gerkmann

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy…

Computer Vision and Pattern Recognition · Computer Science 2019-05-21 Adrian Shajkofci , Michael Liebling

A pupil plane wavefront reconstruction procedure is proposed based on analysis of a sequence of focal plane images corresponding to a sequence of random pupil plane phase probes. The developed method provides the unique nontrivial solution…

Instrumentation and Methods for Astrophysics · Physics 2018-11-13 Eugene Pluzhnik , Dan Sirbu , Ruslan Belikov , Eduardo Bendek , Vladimir N. Dudinov

Modulation-enhanced localization microscopy (MELM) has demonstrated significant improvements in both lateral and axial localization precision compared to conventional single-molecule localization microscopy (SMLM). However, lateral…

Ptychography is a powerful imaging technique that is used in a variety of fields, including materials science, biology, and nanotechnology. However, the accuracy of the reconstructed ptychography image is highly dependent on the accuracy of…

Applied Physics · Physics 2024-06-03 Ming Du , Tao Zhou , Junjing Deng , Daniel J. Ching , Steven Henke , Mathew J. Cherukara

Context: in astronomy, observing large fractions of the sky within a reasonable amount of time implies using large field-of-view (fov) optical instruments that typically have a spatially varying Point Spread Function (PSF). Depending on the…

Computer Vision and Pattern Recognition · Computer Science 2017-03-20 F. M. Ngolè Mboula , J. -L. Starck

Precise centroid estimation plays a critical role in accurate astrometry using telescope images. Conventional centroid estimation fits a template point spread function (PSF) to the image data. Because the PSF is typically not known to high…

Instrumentation and Methods for Astrophysics · Physics 2015-05-27 Chengxing Zhai , Mike Shao , Renaud Goullioud , Bijan Nemati

Optical microscopy is an essential tool in biology and medicine. Imaging thin, yet non-flat objects in a single shot (without relying on more sophisticated sectioning setups) remains challenging as the shallow depth of field that comes with…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Adrian Shajkofci , Michael Liebling

Precise photometric and astrometric measurements on astronomical images require an accurate knowledge of the Point Spread Function (PSF). When the PSF cannot be modelled directly from the image, PSF-reconstruction techniques become the only…

Instrumentation and Methods for Astrophysics · Physics 2020-02-05 D. Massari , A. Marasco , O. Beltramo-Martin , J. Milli , G. Fiorentino , E. Tolstoy , F. Kerber

Generally, wave field reconstructions obtained by phase-retrieval algorithms are noisy, blurred and corrupted by various artifacts such as irregular waves, spots, etc. These disturbances, arising due to many factors such as non-idealities…

Optics · Physics 2012-07-24 Artem Migukin , Mostafa Agour , Vladimir Katkovnik

Robust and accurate camera calibration is essential for 3D reconstruction in light microscopy under circular motion. Conventional methods require either accurate key point matching or precise segmentation of the axial-view images. Both…

Computer Vision and Pattern Recognition · Computer Science 2019-10-31 Yuanhao Guo , Fons J. Verbeek , Ge Yang

We develop for the first time a mathematical framework in which the class of projection algorithms can be applied to high numerical aperture (NA) phase retrieval. Within this framework, we first analyze the basic steps of solving the…

Optimization and Control · Mathematics 2021-12-08 Nguyen Hieu Thao , Oleg Soloviev , Russell Luke , Michel Verhaegen

Reconstruction of the point spread function (PSF) plays an important role in many areas of astronomy, including photometry, astrometry, galaxy morphology, and shear measurement. The atmospheric and instrumental effects are the two main…

Instrumentation and Methods for Astrophysics · Physics 2024-04-25 Pedro Alonso , Jun Zhang , Cong Liu

Optimal error estimation is key to achieve accurate photometry and astrometry. Stellar fluxes and positions in high angular resolution images are typically measured with PSF fitting routines, such as StarFinder. However, the formal…

Instrumentation and Methods for Astrophysics · Physics 2022-08-12 E. Gallego-Cano , R. Schödel , A. T. Gallego-Calvente , A. M. Ghez

Partially-Observable Markov Decision Processes (POMDPs) are typically solved by finding an approximate global solution to a corresponding belief-MDP. In this paper, we offer a new planning algorithm for POMDPs with continuous state, action…

Artificial Intelligence · Computer Science 2012-03-19 Tom Erez , William D. Smart

This paper discusses phase retrieval algorithms for maximum likelihood (ML) estimation from measurements following independent Poisson distributions in very low-count regimes, e.g., 0.25 photon per pixel. To maximize the log-likelihood of…

Information Theory · Computer Science 2022-09-27 Zongyu Li , Kenneth Lange , Jeffrey A. Fessler