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Combinatorial optimization problems play a central role in computer science with many real world applications. A number of relevant problems remain computationally difficult to solve as they lie in the NP-hard complexity class. We present a…

Quantum Physics · Physics 2026-05-11 Kapil Goswami , Peter Schmelcher

Recent advancements in quantum computing and quantum-inspired algorithms have sparked renewed interest in binary optimization. These hardware and software innovations promise to revolutionize solution times for complex problems. In this…

Computed tomography (CT) is an important imaging technique used in medical analysis of the internal structure of the human body. Previously, image segmentation methods were required after acquiring reconstructed CT images to obtain…

Quantum Physics · Physics 2024-09-17 Kyungtaek Jun

Real-world optimization problems must undergo a series of transformations before becoming solvable on current quantum hardware. Even for a fixed problem, the number of possible transformation paths -- from industry-relevant formulations…

Many of the envisioned use-cases for quantum computers involve optimisation processes. While there are many algorithmic primitives to perform the required calculations, all eventually lead to quantum gates operating on quantum bits, with an…

Quantum Physics · Physics 2026-03-26 Lukas Schmidbauer , Elisabeth Lobe , Ina Schaefer , Wolfgang Mauerer

Recent advancements in quantum annealing hardware and numerous studies in this area suggests that quantum annealers have the potential to be effective in solving unconstrained binary quadratic programming problems. Naturally, one may desire…

Quantum Physics · Physics 2019-03-01 Sahar Karimi , Pooya Ronagh

The problem of selecting an appropriate number of features in supervised learning problems is investigated in this paper. Starting with common methods in machine learning, we treat the feature selection task as a quadratic unconstrained…

Quantum Physics · Physics 2023-06-21 Gerhard Hellstern , Vanessa Dehn , Martin Zaefferer

We present a novel formulation of structural design optimization problems specifically tailored to be solved by quantum annealing (QA). Structural design optimization aims to find the best, i.e., material-efficient yet high-performance,…

Computational Engineering, Finance, and Science · Computer Science 2024-04-17 Fabian Key , Lukas Freinberger

We report on a case study in programming an early quantum annealer to attack optimization problems related to operational planning. While a number of studies have looked at the performance of quantum annealers on problems native to their…

Quadratic Unconstrained Binary Optimization (QUBO) is a generic technique to model various NP-hard combinatorial optimization problems in the form of binary variables. The Hamiltonian function is often used to formulate QUBO problems where…

Artificial Intelligence · Computer Science 2023-09-29 Redwan Ahmed Rizvee , Md. Mosaddek Khan

We investigate the use of amplitude amplification on the gate-based model of quantum computing as a means for solving combinatorial optimization problems. This study focuses primarily on QUBO (quadratic unconstrained binary optimization)…

Quantum Physics · Physics 2023-02-02 Daniel Koch , Massimiliano Cutugno , Saahil Patel , Laura Wessing , Paul M. Alsing

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan

Quadratic Unconstrained Binary Optimization (QUBO) problems are prevalent in real-world applications, such as portfolio optimization, but pose significant computational challenges for large-scale instances. We propose a hybrid…

Quantum Physics · Physics 2025-11-06 Soumyadip Das , Suman Kumar Roy , Rahul Rana , M Girish Chandra

In this article, we describe an algorithm for solving Quadratic Unconstrained Binary Optimization problems on the Intel Loihi 2 neuromorphic processor. The solver is based on a hardware-aware fine-grained parallel simulated annealing…

Neural and Evolutionary Computing · Computer Science 2024-08-07 Alessandro Pierro , Philipp Stratmann , Gabriel Andres Fonseca Guerra , Sumedh Risbud , Timothy Shea , Ashish Rao Mangalore , Andreas Wild

Recent advances in quantum technology have led to the development and manufacturing of experimental programmable quantum annealers that promise to solve certain combinatorial optimization problems of practical relevance faster than their…

Quantum Physics · Physics 2016-05-31 Itay Hen , Federico M. Spedalieri

This paper explores the application of Quadratic Unconstrained Binary Optimization (QUBO) models in solving the Travelling Salesman Problem (TSP) through Quantum Annealing algorithms and Graph Neural Networks. Quantum Annealing (QA), a…

Quantum Physics · Physics 2024-10-01 Haoqi He

The ultimate goal of any sparse coding method is to accurately recover from a few noisy linear measurements, an unknown sparse vector. Unfortunately, this estimation problem is NP-hard in general, and it is therefore always approached with…

The quantum approximate optimization algorithm (QAOA) is designed to determine optimum and near optimum solutions of quadratic (and higher order) unconstrained binary optimization (QUBO or HUBO) problems, which in turn accurately model…

Quantum Physics · Physics 2025-03-18 Prashanti Priya Angara , Danylo Lykov , Ulrike Stege , Yuri Alexeev , Hausi Müller

We present Quafu-Qcover, an open-source cloud-based software package designed for combinatorial optimization problems that support both quantum simulators and hardware backends. Quafu-Qcover provides a standardized and complete workflow for…

Quantum Physics · Physics 2023-05-30 BAQIS Quafu Group

Operation management of nuclear power plants consists of several computationally hard problems. Searching for an in-core fuel loading pattern is among them. The main challenge of this combinatorial optimization problem is the exponential…