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Compared with traditional seismic noise attenuation algorithms that depend on signal models and their corresponding prior assumptions, removing noise with a deep neural network is trained based on a large training set, where the inputs are…

Geophysics · Physics 2019-07-23 Siwei Yu , Jianwei Ma , Wenlong Wang

We employ a machine learning-enabled approach to quantum state engineering based on evolutionary algorithms. In particular, we focus on superconducting platforms and consider a network of qubits -- encoded in the states of artificial atoms…

Quantum Physics · Physics 2023-01-26 Jonathon Brown , Mauro Paternostro , Alessandro Ferraro

The potential of synthetic biology techniques for designing complex cellular circuits able to solve complicated computations opens a whole domain of exploration, beyond experiments and theory. Such cellular circuits could be used to carry…

Neurons and Cognition · Quantitative Biology 2013-10-21 Luís F. Seoane , Ricard V. Solé

Can a micron sized sack of interacting molecules understand, and adapt to a constantly-fluctuating environment? Cellular life provides an existence proof in the affirmative, but the principles that allow for life's existence are far from…

Molecular Networks · Quantitative Biology 2022-05-16 William Poole , Thomas Ouldridge , Manoj Gopalkrishnan , Erik Winfree

Stochastic neural networks are a prototypical computational device able to build a probabilistic representation of an ensemble of external stimuli. Building on the relationship between inference and learning, we derive a synaptic plasticity…

Disordered Systems and Neural Networks · Physics 2018-10-23 Luca Saglietti , Federica Gerace , Alessandro Ingrosso , Carlo Baldassi , Riccardo Zecchina

Based on a recently proposed non-equilibrium mechanism for spatial pattern formation [cond-mat/0312366] we study how morphogenesis can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of…

Molecular Networks · Quantitative Biology 2007-05-23 Thimo Rohlf , Stefan Bornholdt

The dynamics of stochastic reaction networks within cells are inevitably modulated by factors considered extrinsic to the network such as for instance the fluctuations in ribsome copy numbers for a gene regulatory network. While several…

Quantitative Methods · Quantitative Biology 2015-06-19 Christoph Zechner , Heinz Koeppl

In response to the continuously changing feedstock supply and market demand for products with different specifications, the processes need to be operated at time-varying operating conditions and targets (e.g., setpoints) to improve the…

Systems and Control · Electrical Eng. & Systems 2024-10-28 Lai Wei , Ryan McCloy , Jie Bao

Inside individual cells, expression of genes is stochastic across organisms ranging from bacterial to human cells. A ubiquitous feature of stochastic expression is burst-like synthesis of gene products, which drives considerable…

Molecular Networks · Quantitative Biology 2016-09-13 Pavol Bokes , Abhyudai Singh

Performing controlled experiments on noisy data is essential in understanding deep learning across noise levels. Due to the lack of suitable datasets, previous research has only examined deep learning on controlled synthetic label noise,…

Machine Learning · Computer Science 2020-08-28 Lu Jiang , Di Huang , Mason Liu , Weilong Yang

This report proposes a novel framework for a rigorous robustness analysis of stochastic biochemical systems. The technique is based on probabilistic model checking. We adapt the general definition of robustness introduced by Kitano to the…

Numerical Analysis · Computer Science 2013-10-18 Lubos Brim , Milan Ceska , Sven Drazan , David Safranek

Quantum systems are inherently open and susceptible to environmental noise, which can have both detrimental and beneficial effects on their dynamics. This phenomenon has been observed in bio-molecular systems, where noise enables novel…

Gene regulatory dynamics is governed by molecular processes and therefore exhibits an inherent stochasticity. However, for the survival of an organism it is a strict necessity that this intrinsic noise does not prevent robust functioning of…

Molecular Networks · Quantitative Biology 2007-05-23 Stefan Braunewell , Stefan Bornholdt

A Network Control System (NCS) consists of control components that interact with the plant over a shared network. The system dynamics of a NCS could be subject to noise arising from randomness in the times at which the data is transmitted…

Systems and Control · Computer Science 2017-04-04 Mohammad Soltani , Abhyudai Singh

Homeostasis is a running theme in biology. Often achieved through feedback regulation strategies, homeostasis allows living cells to control their internal environment as a means for surviving changing and unfavourable environments. While…

Optimization and Control · Mathematics 2016-01-29 Corentin Briat , Ankit Gupta , Mustafa Khammash

An increasing body of evidence suggests that the trial-to-trial variability of spiking activity in the brain is not mere noise, but rather the reflection of a sampling-based encoding scheme for probabilistic computing. Since the precise…

During organismal development, biochemical reaction networks sense and respond to mechanical forces to coordinate embryonic patterning with embryo morphogenesis. Factors such as cortical tension, cell density, and matrix mechanical…

The past decade has seen a revived interest in the unavoidable or intrinsic noise in biochemical and genetic networks arising from the finite copy number of the participating species. That is, rather than modeling regulatory networks in…

Molecular Networks · Quantitative Biology 2015-03-17 Aleksandra M. Walczak , Andrew Mugler , Chris H. WIggins

Understanding cell function requires an accurate description of how noise is transmitted through biochemical networks. We present an analytical result for the power spectrum of the output signal of a biochemical network that takes into…

Molecular Networks · Quantitative Biology 2009-11-11 Sorin Tanase-Nicola , Patrick B. Warren , Pieter Rein ten Wolde

The impact of random fluctuations on the dynamical behavior a complex biological systems is a longstanding issue, whose understanding would shed light on the evolutionary pressure that nature imposes on the intrinsic noise levels and would…

Molecular Networks · Quantitative Biology 2018-01-26 Fabrizio Pucci , Marianne Rooman
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