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Nanovectors (NVs), based on nanostructured matter such as nanoparticles (NPs), have proven to perform as excellent drug delivery systems. However, due to the great variety of potential NVs, including NPs materials and their…

Neural and Evolutionary Computing · Computer Science 2021-12-06 Felipe J. Villaseñor-Cavazos , Daniel Torres-Valladares , Omar Lozano

If we want to train a neural network using any of the most popular optimization algorithms, we are immediately faced with a dilemma: how to set the various optimization and regularization hyperparameters? When computational resources are…

Machine Learning · Computer Science 2025-03-07 Sourabh Medapati , Priya Kasimbeg , Shankar Krishnan , Naman Agarwal , George Dahl

Selecting an optimizer is a central step in the contemporary deep learning pipeline. In this paper, we demonstrate the sensitivity of optimizer comparisons to the hyperparameter tuning protocol. Our findings suggest that the hyperparameter…

Machine Learning · Computer Science 2020-06-17 Dami Choi , Christopher J. Shallue , Zachary Nado , Jaehoon Lee , Chris J. Maddison , George E. Dahl

When and why can a neural network be successfully trained? This article provides an overview of optimization algorithms and theory for training neural networks. First, we discuss the issue of gradient explosion/vanishing and the more…

Machine Learning · Computer Science 2019-12-21 Ruoyu Sun

Despite the recent success of stochastic gradient descent in deep learning, it is often difficult to train a deep neural network with an inappropriate choice of its initial parameters. Even if training is successful, it has been known that…

Machine Learning · Computer Science 2023-02-10 Cheolhyoung Lee , Kyunghyun Cho

Model Predictive Control (MPC) is an optimal control algorithm with strong stability and robustness guarantees. Despite its popularity in robotics and industrial applications, the main challenge in deploying MPC is its high computation…

Systems and Control · Electrical Eng. & Systems 2024-12-31 Camilo Gonzalez , Houshyar Asadi , Lars Kooijman , Chee Peng Lim

The performance of any algorithm will largely depend on the setting of its algorithm-dependent parameters. The optimal setting should allow the algorithm to achieve the best performance for solving a range of optimization problems. However,…

Optimization and Control · Mathematics 2013-12-20 Xin-She Yang , Suash Deb , M. Loomes , M. Karamanoglu

We consider the tuning parameter selection rules for nuclear norm regularized multivariate linear regression (NMLR) in high-dimensional setting. High-dimensional multivariate linear regression is widely used in statistics and machine…

Statistics Theory · Mathematics 2019-01-23 Pan Shang , Lingchen Kong

We address the calibration of a computationally expensive nuclear physics model for which derivative information with respect to the fit parameters is not readily available. Of particular interest is the performance of optimization-based…

Designing resource-efficient Deep Neural Networks (DNNs) is critical to deploy deep learning solutions over edge platforms due to diverse performance, power, and memory budgets. Unfortunately, it is often the case a well-trained ML model…

Machine Learning · Computer Science 2020-06-09 Sheng-Chun Kao , Arun Ramamurthy , Reed Williams , Tushar Krishna

When optimizing a nonlinear objective, one can employ a neural network as a surrogate for the nonlinear function. However, the resulting optimization model can be time-consuming to solve globally with exact methods. As a result, local…

Optimization and Control · Mathematics 2026-03-19 Jiatai Tong , Yilin Zhu , Thiago Serra , Samuel Burer

Recurrent Neural Networks (RNN) are widely used to solve a variety of problems and as the quantity of data and the amount of available compute have increased, so have model sizes. The number of parameters in recent state-of-the-art networks…

Machine Learning · Computer Science 2017-11-08 Sharan Narang , Erich Elsen , Gregory Diamos , Shubho Sengupta

The use of machine learning methods to tackle challenging physical layer signal processing tasks has attracted significant attention. In this work, we focus on the use of neural networks (NNs) to perform pilot-assisted channel estimation in…

Signal Processing · Electrical Eng. & Systems 2020-02-26 Michel van Lier , Alexios Balatsoukas-Stimming , Henk Corporaaal , Zoran Zivkovic

To facilitate widespread adoption of automated engineering design techniques, existing methods must become more efficient and generalizable. In the field of topology optimization, this requires the coupling of modern optimization methods…

Computational Engineering, Finance, and Science · Computer Science 2024-02-23 Connor N. Mallon , Aaron W. Thornton , Matthew R. Hill , Santiago Badia

Sampling-based path planning algorithms suffer from heavy reliance on uniform sampling, which accounts for unreliable and time-consuming performance, especially in complex environments. Recently, neural-network-driven methods predict…

Robotics · Computer Science 2023-08-17 Yuan Huang , Cheng-Tien Tsao , Tianyu Shen , Hee-Hyol Lee

Machine learning models are often tuned by nesting optimization of model weights inside the optimization of hyperparameters. We give a method to collapse this nested optimization into joint stochastic optimization of weights and…

Machine Learning · Computer Science 2018-03-09 Jonathan Lorraine , David Duvenaud

Neural networks are powerful models that have a remarkable ability to extract patterns that are too complex to be noticed by humans or other machine learning models. Neural networks are the first class of models that can train end-to-end…

Machine Learning · Computer Science 2021-08-05 Ibrahim Alshubaily

Machine learning tasks are generally formulated as optimization problems, where one searches for an optimal function within a certain functional space. In practice, parameterized functional spaces are considered, in order to be able to…

Artificial Intelligence · Computer Science 2024-12-13 Manon Verbockhaven , Sylvain Chevallier , Guillaume Charpiat , Théo Rudkiewicz

The design of neural network architectures is frequently either based on human expertise using trial/error and empirical feedback or tackled via large scale reinforcement learning strategies performed over distinct discrete architecture…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Yunyang Xiong , Ronak Mehta , Vikas Singh

Path planning is typically considered in Artificial Intelligence as a graph searching problem and R* is state-of-the-art algorithm tailored to solve it. The algorithm decomposes given path finding task into the series of subtasks each of…

Artificial Intelligence · Computer Science 2015-11-04 Konstantin Yakovlev , Egor Baskin , Ivan Hramoin