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To better understand mortality change with age capturing the variability in individuals' rates of aging, we performed comprehensive analysis of statistical properties of a cumulative index of age-associated disorders (deficits), called a…

Populations and Evolution · Quantitative Biology 2007-05-23 A. Kulminski , A. Yashin , I. Akushevich , S. Ukraintseva , K. Land , K. Arbeev , K. Manton

Continuous-time multi-state survival models can be used to describe health-related processes over time. In the presence of interval-censored times for transitions between the living states, the likelihood is constructed using transition…

Methodology · Statistics 2017-03-24 Robson J. M. Machado , Ardo van den Hout

The process of integration of inputs from several sensory modalities in the human brain is referred to as multisensory integration. Age-related cognitive decline leads to a loss in the ability of the brain to conceive multisensory inputs.…

Signal Processing · Electrical Eng. & Systems 2023-05-02 Prerna Singh , Ayush Tripathi , Lalan Kumar , Tapan Kumar Gandhi

The significance of mortality modeling extends across multiple research areas, ranging from life insurance valuation to optimal lifetime decision-making. Existing approaches, such as mortality laws and factor-based models, often fall short…

Applications · Statistics 2024-10-23 Xiaobai Zhu , Kenneth Q. Zhou , Zijia Wang

The existing life table method needs to calculate the age-specific mortality first, not only has too many and complicated calculation steps, but also introduces the multiple approximation to bring error. This paper redefines the probability…

Other Quantitative Biology · Quantitative Biology 2020-04-21 Weidong Huang

In recent years, a wide range of mortality models has been proposed to address the diverse factors influencing mortality rates, which has highlighted the need to perform model selection. Traditional mortality model selection methods, such…

Methodology · Statistics 2025-10-22 Alex Diana , Jackie Wong Siaw Tze , Aniketh Pittea

We introduce a nonparametric bootstrap procedure based on a dynamic factor model to construct pointwise prediction intervals for period life-table death counts. The age distribution of death counts is an example of constrained data, which…

Methodology · Statistics 2025-07-17 Han Lin Shang

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

Machine Learning · Statistics 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

This paper sets out a forecasting method that employs a mixture of parametric functions to capture the pattern of fertility with respect to age. The overall level of cohort fertility is decomposed over the range of fertile ages using a…

Applications · Statistics 2019-09-23 Jason Hilton , Erengul Dodd , Jonathan J. Forster , Peter W. F. Smith , Jakub Bijak

We introduce a compositional power transformation, known as an {\alpha}-transformation, to model and forecast a time series of life-table death counts, possibly with zero counts observed at older ages. As a generalisation of the isometric…

Applications · Statistics 2024-09-19 Han Lin Shang , Steven Haberman

For the assessment of the financial soundness of a pension fund, it is necessary to take into account mortality forecasting so that longevity risk is consistently incorporated into future cash flows. In this article, we employ machine…

Machine Learning · Statistics 2025-04-09 Eduardo Fraga L. de Melo , Helton Graziadei , Rodrigo Targino

Aggregated health data such as claims data from health insurances become more and more available for research purposes. Estimates of excess mortality from prevalence and incidence of a chronic condition have only been possible for ages 50…

Populations and Evolution · Quantitative Biology 2019-08-13 Ralph Brinks

Survival analysis serves as a fundamental component in numerous healthcare applications, where the determination of the time to specific events (such as the onset of a certain disease or death) for patients is crucial for clinical…

Artificial Intelligence · Computer Science 2025-10-23 Siqi Li , Yuqing Shang , Ziwen Wang , Qiming Wu , Chuan Hong , Yilin Ning , Di Miao , Marcus Eng Hock Ong , Bibhas Chakraborty , Nan Liu

Many existing mortality models follow the framework of classical factor models, such as the Lee-Carter model and its variants. Latent common factors in factor models are defined as time-related mortality indices (such as $\kappa_t$ in the…

Methodology · Statistics 2021-02-04 Lingyu He , Fei Huang , Jianjie Shi , Yanrong Yang

In this paper, we introduce some new notions of aging based on geometric, harmonic means of failure rate and aging intensity function. We define a generalized version of aging functions called specific interval-average geometric hazard…

Statistics Theory · Mathematics 2024-07-02 Subarna Bhattacharjee , Ananda Sen , Sabana Anwar , Aninda Kumar Nanda

Forecast combination -- the aggregation of individual forecasts from multiple experts or models -- is a proven approach to economic forecasting. To date, research on economic forecasting has concentrated on local combination methods, which…

Econometrics · Economics 2024-03-12 Ryan Thompson , Yilin Qian , Andrey L. Vasnev

In a recent article in PNAS, Case and Deaton show a figure illustrating "a marked increase in the all-cause mortality of middle-aged white non-Hispanic men and women in the United States between 1999 and 2013." The authors state that their…

Applications · Statistics 2016-04-27 Andrew Gelman , Jonathan Auerbach

We developed two new alternatives to signature-based, spatial autoregressive models. In a simulation study, we found that the new models performed at least as well as existing approaches but presented shorter computation times. We then used…

Methodology · Statistics 2025-12-01 Camille Frévent

This paper describes a methodology for automated univariate time series forecasting using regression trees and their ensembles: bagging and random forests. The key aspects that are addressed are: the use of an autoregressive approach and…

Machine Learning · Computer Science 2026-02-03 Francisco Martínez , María P. Frías

This study introduces a novel generalized additive mixed model (GAMM) for mortality modelling, utilizing the mortality covariate $k_t$ as proposed by Dastranj-Kolar. Our findings indicate that the GAMM effectively addresses this…

Applications · Statistics 2025-11-18 Reza Dastranj , Martin Kolar