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We introduce a novel personalized Gaussian Process Experts (pGPE) model for predicting per-subject ADAS-Cog13 cognitive scores -- a significant predictor of Alzheimer's Disease (AD) in the cognitive domain -- over the future 6, 12, 18, and…

Machine Learning · Computer Science 2019-06-11 Ognjen Rudovic , Yuria Utsumi , Ricardo Guerrero , Kelly Peterson , Daniel Rueckert , Rosalind W. Picard

Background: Artificial Intelligence (AI) clinical decision support (CDS) systems have the potential to augment surgical risk assessments, but successful adoption depends on an understanding of end-user needs and current workflows. This…

Human-Computer Interaction · Computer Science 2025-04-04 Andrea E Davidson , Jessica M Ray , Yulia Levites Strekalova , Parisa Rashidi , Azra Bihorac

Introduction: Timely care in a specialised neuro-intensive therapy unit (ITU) reduces mortality and hospital stays, with planned admissions being safer than unplanned ones. However, post-operative care decisions remain subjective. This…

Over the last century, risk scores have been the most popular form of predictive model used in healthcare and criminal justice. Risk scores are sparse linear models with integer coefficients; often these models can be memorized or placed on…

Machine Learning · Computer Science 2022-10-13 Jiachang Liu , Chudi Zhong , Boxuan Li , Margo Seltzer , Cynthia Rudin

We propose a multivariate GARCH model for non-stationary health time series by modifying the variance of the observations of the standard state space model. The proposed model provides an intuitive way of dealing with heteroskedastic data…

Methodology · Statistics 2023-03-16 Zayd Omar , David A. Stephens , Alexandra M. Schmidt , David L. Buckeridge

Continuous blood pressure (BP) monitoring is essential for timely diagnosis and intervention in critical care settings. However, BP varies significantly across individuals, this inter-patient variability motivates the development of…

Machine Learning · Computer Science 2024-09-10 Cheng Wan , Chenjie Xie , Longfei Liu , Dan Wu , Ye Li

We develop a Gaussian process ("GP") framework for modeling mortality rates and mortality improvement factors. GP regression is a nonparametric, data-driven approach for determining the spatial dependence in mortality rates and jointly…

Methodology · Statistics 2018-04-13 Mike Ludkovski , Jimmy Risk , Howard Zail

Intensive Care Units (ICUs) provide critical care and life support for most severely ill and injured patients in the hospital. With the need for ICUs growing rapidly and unprecedentedly, especially during COVID-19, accurately identifying…

Artificial Intelligence · Computer Science 2024-12-04 Weihan Xu

Modern precision medicine aims to utilize real-world data to provide the best treatment for an individual patient. An individualized treatment rule (ITR) maps each patient's characteristics to a recommended treatment scheme that maximizes…

Applications · Statistics 2025-01-07 Andong Wang , Kelly Wentzlof , Johnny Rajala , Miontranese Green , Yunshu Zhang , Shu Yang

Ecological Momentary Assessment provides real-time data on suicidal thoughts and behaviors, but predicting suicide attempts remains challenging due to their rarity and patient heterogeneity. We show that single models fit to all patients…

Machine Learning · Statistics 2025-11-25 Genesis Hang , Annie Chen , Hope Neveux , Matthew K. Nock , Yaniv Yacoby

Motivated by the need to study the molecular mechanism underlying Type 1 Diabetes (T1D) with the gene expression data collected from both the patients and healthy controls at multiple time points, we propose an innovative method for jointly…

Methodology · Statistics 2018-12-10 Bochao Jia , Faming Liang , the TEDDY Study Group

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Problem lists are intended to provide clinicians with a relevant summary of patient medical issues and are embedded in many electronic health record systems. Despite their importance, problem lists are often cluttered with resolved or…

Information Retrieval · Computer Science 2020-08-05 Justin Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Patient stratification identifying clinically meaningful subgroups is essential for advancing personalized medicine through improved diagnostics and treatment strategies. Electronic health records (EHRs), particularly those from intensive…

Machine Learning · Computer Science 2025-06-09 Dimitrios Proios , Alban Bornet , Anthony Yazdani , Jose F Rodrigues , Douglas Teodoro

Contemporary patient surveillance systems have streamlined central surveillance into the electronic health record interface. They are able to process the sheer volume of patient data by adopting machine learning approaches. However, these…

Computers and Society · Computer Science 2021-11-04 Nazifa M Shemonti , Shifat Uddin , Saifur Rahman , Tarem Ahmed , Mohammad Faisal Uddin

We propose and experimentally motivate a new methodology to support decision-making processes in healthcare with artificial intelligence based on personal rankings of care decision making steps that can be identified with our methodology,…

Human-Computer Interaction · Computer Science 2022-05-18 Lauri Lahti

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

Methodology · Statistics 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

We consider the problem of modeling cardiovascular responses to physical activity and sleep changes captured by wearable sensors in free living conditions. We use an attentional convolutional neural network to learn parsimonious signatures…

Machine Learning · Computer Science 2018-12-06 Haraldur T. Hallgrímsson , Filip Jankovic , Tim Althoff , Luca Foschini

Clinical outcome prediction plays an important role in stroke patient management. From a machine learning point-of-view, one of the main challenges is dealing with heterogeneous data at patient admission, i.e. the image data which are…

Image and Video Processing · Electrical Eng. & Systems 2022-05-12 Nima Hatami , Tae-Hee Cho , Laura Mechtouff , Omer Faruk Eker , David Rousseau , Carole Frindel

Intensive Care Units are complex, data-rich environments where critically ill patients are treated using variety of clinical equipment. The data collected using this equipment can be used clinical staff to gain insight into the condition of…

Human-Computer Interaction · Computer Science 2024-10-23 Marceli Wac , Raul Santos-Rodriguez , Chris McWilliams , Christopher Bourdeaux
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