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The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Crossover designs randomly assign each unit to receive a sequence of treatments. By comparing outcomes within the same unit, these designs can effectively eliminate between-unit variation and facilitate the identification of both…

Methodology · Statistics 2026-04-21 Zhichao Jiang , Peng Ding

In real applications, generally small data sets can be obtained. At present, most of the practical applications of machine learning use classic models based on big data to solve the problem of small data sets. However, the deep neural…

Computer Vision and Pattern Recognition · Computer Science 2022-12-02 Jingyi Zhou , Qingfang He , Zhiying Lin

Open-world object detection (OWOD) requires incrementally detecting known categories while reliably identifying unknown objects. Existing methods primarily focus on improving unknown recall, yet overlook interpretability, often leading to…

Computer Vision and Pattern Recognition · Computer Science 2026-02-25 Xueqiang Lv , Shizhou Zhang , Yinghui Xing , Di Xu , Peng Wang , Yanning Zhang

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

Vessel image segmentation plays a pivotal role in medical diagnostics, aiding in the early detection and treatment of vascular diseases. While segmentation based on deep learning has shown promising results, effectively segmenting small…

Image and Video Processing · Electrical Eng. & Systems 2023-08-24 Ruiqiang Xiao , Zhuoyue Wan

A new ensemble framework for interpretable model called Linear Iterative Feature Embedding (LIFE) has been developed to achieve high prediction accuracy, easy interpretation and efficient computation simultaneously. The LIFE algorithm is…

Machine Learning · Statistics 2021-03-19 Agus Sudjianto , Jinwen Qiu , Miaoqi Li , Jie Chen

Ultrasound images vary widely across scanners, operators, and anatomical targets, which often causes models trained in one setting to generalize poorly to new hospitals and clinical conditions. The Foundation Model Challenge for Ultrasound…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Ufaq Khan , L. D. M. S. Sai Teja , Ayuba Shakiru , Mai A. Shaaban , Yutong Xie , Muhammad Bilal , Muhammad Haris Khan

Cancer survival prediction from whole slide images (WSIs) is a challenging task in computational pathology due to the large size, irregular shape, and high granularity of the WSIs. These characteristics make it difficult to capture the full…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Rustin Soraki , Huayu Wang , Joann G. Elmore , Linda Shapiro

This paper presents a novel incremental learning algorithm for pedestrian motion prediction, with the ability to improve the learned model over time when data is incrementally available. In this setup, trajectories are modeled as simple…

Robotics · Computer Science 2019-11-22 Golnaz Habibi , Nikita Japuria , Jonathan P. How

Understanding why a model made a certain prediction is crucial in many data science fields. Interpretable predictions engender appropriate trust and provide insight into how the model may be improved. However, with large modern datasets the…

Artificial Intelligence · Computer Science 2016-12-09 Scott Lundberg , Su-In Lee

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Interpretability is a crucial aspect of machine learning models that enables humans to understand and trust the decision-making process of these models. In many real-world applications, the interpretability of models is essential for legal,…

Machine Learning · Statistics 2023-07-18 Shree Charran R , Sandipan Das Mahapatra

Although deep learning has achieved remarkable success in various scientific machine learning applications, its opaque nature poses concerns regarding interpretability and generalization capabilities beyond the training data.…

Machine Learning · Computer Science 2024-04-18 Amirhossein Arzani , Lingxiao Yuan , Pania Newell , Bei Wang

Uncertainty estimation is a key component in any deployed machine learning system. One way to evaluate uncertainty estimation is using "out-of-distribution" (OoD) detection, that is, distinguishing between the training data distribution and…

Machine Learning · Computer Science 2021-12-03 Haiwen Huang , Joost van Amersfoort , Yarin Gal

To address the issues of stability and fidelity in interpretable learning, a novel interpretable methodology, ensemble interpretation, is presented in this paper which integrates multi-perspective explanation of various interpretation…

Machine Learning · Computer Science 2023-12-12 Chao Min , Guoyong Liao , Guoquan Wen , Yingjun Li , Xing Guo

Accurate and interpretable survival analysis remains a core challenge in oncology. With growing multimodal data and the clinical need for transparent models to support validation and trust, this challenge increases in complexity. We propose…

Artificial Intelligence · Computer Science 2025-09-29 Mafalda Malafaia , Peter A. N. Bosman , Coen Rasch , Tanja Alderliesten

Developing effective multimodal data fusion strategies has become increasingly essential for improving the predictive power of statistical machine learning methods across a wide range of applications, from autonomous driving to medical…

Machine Learning · Computer Science 2025-07-29 Ziyi Liang , Annie Qu , Babak Shahbaba

When predictive models are used to support complex and important decisions, the ability to explain a model's reasoning can increase trust, expose hidden biases, and reduce vulnerability to adversarial attacks. However, attempts at…

Machine Learning · Computer Science 2019-07-11 Dimitris Bertsimas , Arthur Delarue , Patrick Jaillet , Sebastien Martin

Deep generative models have recently yielded encouraging results in producing subjectively realistic samples of complex data. Far less attention has been paid to making these generative models interpretable. In many scenarios, ranging from…

Machine Learning · Computer Science 2018-02-21 Samuel Ainsworth , Nicholas Foti , Adrian KC Lee , Emily Fox