Related papers: Scan-less confocal phase microscopy based on dual …
We introduce a novel laser-scanning optical microscopy technique that employs optical-frequency-comb (OFC) lasers. This method facilitates multimodal spectroscopic imaging by analyzing interferograms produced via a dual-comb spectroscopic…
Dual-comb microscopy (DCM), an interesting imaging modality based on the optical-frequency-comb (OFC) mode and image pixel one-to-one correspondence, benefits from scan-less full-field imaging and simultaneous confocal amplitude and phase…
This paper presents a coherent linking approach between confocal amplitude and confocal phase images acquired using dual-comb microscopy (DCM). DCM combines the advantages of confocal laser microscopy and quantitative phase microscopy,…
We demonstrate a three-dimensional (3D) optical diffraction tomographic technique with optimal frequency combination (OFC-ODT) for the 3D quantitative phase imaging of unlabeled specimens. Three sets of through-focus intensity images are…
Dual-comb microscopy (DCM), based on a combination of dual-comb spectroscopy (DCS) with two-dimensional spectral encoding (2D-SE), is a promising method for scan-less confocal laser microscopy giving an amplitude and phase image contrast…
We have developed a hyperspectral imaging scheme that involves a combination of dual-comb spectroscopy and Hadamard-transform-based single-pixel imaging. The scheme enables us to obtain 12,000 hyperspectral images of amplitude and phase at…
Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…
Optical coherence tomography (OCT) microscope (OCM) uses a high-numerical-aperture objective to achieve cellular-level lateral resolution. However, its practical imaging depth range is limited by the depth of focus (DOF). Although…
Optical frequency combs (OFCs) are frequency rulers essential for precision metrology, next generation navigation, and testing of fundamental physics. Despite intense efforts, chip-integrated OFCs remain laboratory-bound, unable to fulfill…
Optical frequency comb (OFC) technology has been the cornerstone for scientific breakthroughs such as precision frequency metrology, redefinition of time, extreme light-matter interaction, and attosecond sciences. While the current…
Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool for quantitative fluorescence imaging because fluorescence lifetime is independent of concentration of fluorescent molecules or excitation/detection efficiency and is robust…
We demonstrate Optical-Resolution Photoacoustic Microscopy (OR-PAM), where the optical field is focused and scanned using Digital Phase Conjugation (DPC) through a multimode fiber. The focus is scanned across the field of view using digital…
This paper introduces a two-and multi-level phase mask design for improved depth of focus. A novel technique is proposed incorporating cubic and generalized cubic wavefront coding (WFC). The obtained system is optical-electronic requiring…
Endoscopic imaging is essential for real-time visualization of internal organs, yet conventional systems remain bulky, complex, and expensive due to their reliance on large, multi-element optical components. This limits their accessibility…
We report the first photoacoustic detection scheme using an optical frequency comb - the optical frequency comb photoacoustic spectroscopy (OFC-PAS). OFC-PAS combines the broad spectral coverage and the high resolution of OFCs with the…
Imaging through optical multimode fibers (MMFs) has the potential to enable hair-thin endoscopes that reduce the invasiveness of imaging deep inside tissues and organs. Current approaches predominantly require active wavefront shaping and…
We report on a method to obtain confocal imaging through multimode fibers using optical correlation. First, we measure the fiber's transmission matrix in a calibration step. This allows us to create focused spots at one end of the fiber by…
Optical frequency combs are increasingly used in applications such as optical communications, radio signal processing, and dual-comb spectroscopy. Many of these applications require a broad, flat spectrum with tunable center wavelength and…
High finesse frequency combs (HFC) with large ratio of the frequency spacing to the width of the spectral components have demonstrated remarkable results in many applications such as precision spectroscopy and metrology. We found that low…
We demonstrate optical frequency comb Faraday rotation spectroscopy (OFC-FRS) for broadband interference-free detection of paramagnetic species. The system is based on a femtosecond doubly resonant optical parametric oscillator and a…