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Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Xiaofeng Liu , Fangxu Xing , Chao Yang , C. -C. Jay Kuo , Georges ElFakhri , Jonghye Woo

Parametric imaging of nuclear medicine data exploits dynamic functional images in order to reconstruct maps of kinetic parameters related to the metabolism of a specific tracer injected in the biological tissue. From a computational…

Numerical Analysis · Mathematics 2019-08-30 Serena Crisci , Michele Piana , Valeria Ruggiero , Mara Scussolini

Deformable medical image registration is a fundamental task in medical image analysis with applications in disease diagnosis, treatment planning, and image-guided interventions. Despite significant advances in deep learning based…

Machine Learning · Computer Science 2026-02-10 Muhammad Zafar Iqbal , Ghazanfar Farooq Siddiqui , Anwar Ul Haq , Imran Razzak

Uncompressed clinical data from modern positron emission tomography (PET) scanners are very large, exceeding 350 million data points (projection bins). The last decades have seen tremendous advancements in mathematical imaging tools many of…

Medical Physics · Physics 2020-01-08 Matthias J. Ehrhardt , Pawel Markiewicz , Carola-Bibiane Schönlieb

Whole-body Positron Emission Tomography (PET) registration is essential for multi-parametric tumor characterization and assessment of metastatic disease progression. In deep learning-based deformable registration, the dense displacement…

Image and Video Processing · Electrical Eng. & Systems 2026-04-28 Xiangcen Wu , Ruohua Chen , Sichun Li , Qianye Yang , Sheng Liu , Jianjun Liu , Zhaoheng Xie

We present a fast learning-based algorithm for deformable, pairwise 3D medical image registration. Current registration methods optimize an objective function independently for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

CT and MRI are two of the most informative modalities in spinal diagnostics and treatment planning. CT is useful when analysing bony structures, while MRI gives information about the soft tissue. Thus, fusing the information of both…

Percutaneous Coronary Intervention (PCI) is a minimally invasive procedure that improves coronary blood flow and treats coronary artery disease. Although PCI typically requires 2D X-ray angiography (XRA) to guide catheter placement at…

Image and Video Processing · Electrical Eng. & Systems 2025-06-02 Peng Qi , Wenxi Qu , Tianliang Yao , Haonan Ma , Dylan Wintle , Yinyi Lai , Giorgos Papanastasiou , Chengjia Wang

Advanced navigation techniques in image-guided interventions and surgical robotics require the rapid and precise alignment of 3D preoperative volumes (e.g., CT, MRI) to 2D intraoperative images (e.g., X-ray fluoroscopy). However, existing…

Computerized registration between maxillofacial cone-beam computed tomography (CT) images and a scanned dental model is an essential prerequisite in surgical planning for dental implants or orthognathic surgery. We propose a novel method…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Minyoung Chung , Jingyu Lee , Wisoo Song , Youngchan Song , Il-Hyung Yang , Jeongjin Lee , Yeong-Gil Shin

We propose a novel non-rigid image registration algorithm that is built upon fully convolutional networks (FCNs) to optimize and learn spatial transformations between pairs of images to be registered. Different from most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2017-09-05 Hongming Li , Yong Fan

Rigid registration aims to determine the translations and rotations necessary to align features in a pair of images. While recent machine learning methods have become state-of-the-art for linear and deformable registration across subjects,…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jingru Fu , Adrian V. Dalca , Bruce Fischl , Rodrigo Moreno , Malte Hoffmann

Affine registration plays a crucial role in PET/CT imaging, where aligning PET with CT images is challenging due to their respective functional and anatomical representations. Despite the significant promise shown by recent deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Junyu Chen , Yihao Liu , Shuwen Wei , Aaron Carass , Yong Du

Registration of brain MRI images requires to solve a deformation field, which is extremely difficult in aligning intricate brain tissues, e.g., subcortical nuclei, etc. Existing efforts resort to decomposing the target deformation field…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Jinxin Lv , Zhiwei Wang , Hongkuan Shi , Haobo Zhang , Sheng Wang , Yilang Wang , Qiang Li

Purpose: The fusion of transrectal ultrasound (TRUS) and magnetic resonance (MR) images for guiding targeted prostate biopsy has significantly improved the biopsy yield of aggressive cancers. A key component of MR-TRUS fusion is image…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Grant Haskins , Jochen Kruecker , Uwe Kruger , Sheng Xu , Peter A. Pinto , Brad J. Wood , Pingkun Yan

The interpretation of prostate MRI suffers from low agreement across radiologists due to the subtle differences between cancer and normal tissue. Image registration addresses this issue by accurately mapping the ground-truth cancer labels…

The diagnosis of brain cancer relies heavily on medical imaging techniques, with MRI being the most commonly used. It is necessary to perform automatic segmentation of brain tumors on MRI images. This project intends to build an MRI…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Yuxiang Hu , Haowei Yang , Ting Xu , Shuyao He , Jiajie Yuan , Haozhang Deng

Beta-amyloid positron emission tomography (A$\beta$-PET) imaging has become a critical tool in Alzheimer's disease (AD) research and diagnosis, providing insights into the pathological accumulation of amyloid plaques, one of the hallmarks…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Qing Lyu , Jin Young Kim , Jeongchul Kim , Christopher T Whitlow