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Despite the fact that they do not consider the temporal nature of data, classic dimensionality reduction techniques, such as PCA, are widely applied to time series data. In this paper, we introduce a factor decomposition specific for time…

Machine Learning · Statistics 2014-06-17 Diego Vidaurre , Iead Rezek , Samuel L. Harrison , Stephen S. Smith , Mark Woolrich

Predictive modeling from high-dimensional genomic data is often preceded by a dimension reduction step, such as principal components analysis (PCA). However, the application of PCA is not straightforward for multi-source data, wherein…

Quantitative Methods · Quantitative Biology 2017-07-19 Adam Kaplan , Eric F. Lock

With ever-increasing application of machine learning models in various domains such as image classification, speech recognition and synthesis, and health care, designing efficient hardware for these models has gained a lot of popularity.…

Machine Learning · Computer Science 2018-01-22 Mahdi Nazemi , Amir Erfan Eshratifar , Massoud Pedram

Dimensionality reduction is a main step in the learning process which plays an essential role in many applications. The most popular methods in this field like SVD, PCA, and LDA, only can be applied to data with vector format. This means…

Machine Learning · Computer Science 2019-03-01 Soheil Ahmadi , Mansoor Rezghi

We introduce a framework for model reduction of chain models for dissipative particle dynamics (DPD) simulations, where the characteristic size of the chain, pressure, density, and temperature are preserved. The proposed methodology reduces…

Soft Condensed Matter · Physics 2016-05-04 Nicolas Moreno , Suzana P. Nunes , Victor M. Calo

Motivation: The high dimensionality of genomic data calls for the development of specific classification methodologies, especially to prevent over-optimistic predictions. This challenge can be tackled by compression and variable selection,…

Methodology · Statistics 2021-04-10 G. Durif , L. Modolo , J. Michaelsson , J. E. Mold , S. Lambert-Lacroix , F. Picard

Predicting the solubility of given molecules remains crucial in the pharmaceutical industry. In this study, we revisited this extensively studied topic, leveraging the capabilities of contemporary computing resources. We employed two…

Quantitative Methods · Quantitative Biology 2024-01-08 John Ho , Zhao-Heng Yin , Colin Zhang , Nicole Guo , Yang Ha

Principal Component Analysis (PCA) is a fundamental data preprocessing tool in the world of machine learning. While PCA is often thought of as a dimensionality reduction method, the purpose of PCA is actually two-fold: dimension reduction…

Machine Learning · Computer Science 2023-01-25 Arpita Gang , Waheed U. Bajwa

With the rapid development of deep learning, the increasing complexity and scale of parameters make training a new model increasingly resource-intensive. In this paper, we start from the classic convolutional neural network (CNN) and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jiacong Hu , Jing Gao , Jingwen Ye , Yang Gao , Xingen Wang , Zunlei Feng , Mingli Song

Principal component analysis (PCA) is one of the most popular dimension reduction techniques in statistics and is especially powerful when a multivariate distribution is concentrated near a lower-dimensional subspace. Multivariate extreme…

Methodology · Statistics 2025-07-15 Felix Reinbott , Anja Janßen

Medical imaging involves high-dimensional data, yet their acquisition is obtained for limited samples. Multivariate predictive models have become popular in the last decades to fit some external variables from imaging data, and standard…

Applications · Statistics 2018-06-18 Jérôme-Alexis Chevalier , Joseph Salmon , Bertrand Thirion

Dimensionality reduction is a classical technique widely used for data analysis. One foundational instantiation is Principal Component Analysis (PCA), which minimizes the average reconstruction error. In this paper, we introduce the…

Discrete Mathematics · Computer Science 2020-06-17 Uthaipon Tantipongpipat , Samira Samadi , Mohit Singh , Jamie Morgenstern , Santosh Vempala

Accurate classification of breast cancer subtypes from gene expression data is critical for diagnosis and treatment selection. However, such datasets are characterized by high dimensionality and limited sample size, posing challenges for…

Machine Learning · Computer Science 2026-05-08 Meena Al Hasani

Due to the substantial scale of Large Language Models (LLMs), the direct application of conventional compression methodologies proves impractical. The computational demands associated with even minimal gradient updates present challenges,…

Machine Learning · Computer Science 2023-12-13 Arnav Chavan , Nahush Lele , Deepak Gupta

Probabilistic principal component analysis (PPCA) seeks a low dimensional representation of a data set in the presence of independent spherical Gaussian noise, Sigma = (sigma^2)*I. The maximum likelihood solution for the model is an…

Machine Learning · Statistics 2011-06-23 Alfredo A. Kalaitzis , Neil D. Lawrence

We present a new combinatorial model for identifying regulatory modules in gene co-expression data using a decomposition into weighted cliques. To capture complex interaction effects, we generalize the previously-studied weighted edge…

Data Structures and Algorithms · Computer Science 2021-09-08 Madison Cooley , Casey S. Greene , Davis Issac , Milton Pividori , Blair D. Sullivan

We propose a provably convergent method, called Efficient Learned Descent Algorithm (ELDA), for low-dose CT (LDCT) reconstruction. ELDA is a highly interpretable neural network architecture with learned parameters and meanwhile retains…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Qingchao Zhang , Mehrdad Alvandipour , Wenjun Xia , Yi Zhang , Xiaojing Ye , Yunmei Chen

The development and use of dimension reduction methods is prevalent in modern statistical literature. This paper reviews a class of dimension reduction techniques which aim to simultaneously select relevant predictors and find clusters…

Methodology · Statistics 2022-02-18 Suchit Mehrotra

Leveraging the large body of work devoted in recent years to describe redundancy and synergy in multivariate interactions among random variables, we propose a novel approach to quantify cooperative effects in feature importance, one of the…

Data Analysis, Statistics and Probability · Physics 2025-03-14 Marlis Ontivero-Ortega , Luca Faes , Jesus M Cortes , Daniele Marinazzo , Sebastiano Stramaglia

Peptide compounds demonstrate considerable potential as therapeutic agents due to their high target affinity and low toxicity, yet their drug development is constrained by their low membrane permeability. Molecular weight and peptide length…

Machine Learning · Computer Science 2025-05-26 Shuang Wu , Meijie Wang , Lun Yu
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