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Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

Under many physiological and pathological conditions such as division and migration, cells undergo dramatic deformations, under which their mechanical integrity is supported by cytoskeletal networks (i.e. intermediate filaments, F-actin,…

Biological Physics · Physics 2023-06-13 Haiqian Yang , Thomas Henzel , Eric M. Stewart , Lallit Anand , Ming Guo

Cell polarization is a critical process that separates molecular species into two distinct regions in prokaryotic and eukaryotic cells, guiding biological processes such as cell division and cell differentiation. Although several underlying…

Molecular Networks · Quantitative Biology 2025-01-28 Yixuan Chen , Guoye Guan , Lei-Han Tang , Chao Tang

We provide a minimal continuum model for mesoscale plasticity, explaining the cellular dislocation structures observed in deformed crystals. Our dislocation density tensor evolves from random, smooth initial conditions to form self-similar…

Materials Science · Physics 2010-09-03 Yong S. Chen , Woosong Choi , Stefanos Papanikolaou , James P. Sethna

Ordered polarity alignment of a cell population plays a vital role in biology, such as in hair follicle alignment and asymmetric cell division. Here, we propose a theoretical framework for the understanding of generic dynamical properties…

Pattern Formation and Solitons · Physics 2016-12-13 Kaori Sugimura , Hiroshi Kori

Cellular differentiation in a developping organism is studied via a discrete bistable reaction-diffusion model. A system of undifferentiated cells is allowed to receive an inductive signal emenating from its environment. Depending on the…

Pattern Formation and Solitons · Physics 2009-11-10 Gabor Fath , Zbigniew Domanski

Ionic crystals, such as solid electrolytes and complex oxides, are central to modern technologies for energy storage, sensing, actuation, and other functional applications. An important fundamental issue in the atomic and quantum-scale…

Materials Science · Physics 2026-02-12 Shoham Sen , Yang Wang , Timothy Breitzman , Kaushik Dayal

We study oriented percolation on random causal triangulations, those are random planar graphs obtained roughly speaking by adding horizontal connections between vertices of an infinite tree. When the underlying tree is a geometric…

Probability · Mathematics 2023-07-10 David Corlin Marchand

Planar cell polarity (PCP), the coherent in-plane polarization of a tissue on multicellular length scales, provides directional information that guides a multitude of developmental processes at cellular and tissue levels. While it is…

Biological Physics · Physics 2020-07-01 Shahriar Shadkhoo , Madhav Mani

Deterministic classical cellular automata can be in two phases, depending on how irreversible the dynamical rules are. In the strongly irreversible phase, trajectories with different initial conditions coalesce quickly, while in the weakly…

Statistical Mechanics · Physics 2026-03-25 Adam Nahum , Sthitadhi Roy

Percolation is the simplest fundamental model in statistical mechanics that exhibits phase transitions signaled by the emergence of a giant connected component. Despite its very simple rules, percolation theory has successfully been applied…

Statistical Mechanics · Physics 2015-06-09 Abbas Ali Saberi

When it is polarised, a cell develops an asymmetric distribution of specific molecular markers, cytoskeleton and cell membrane shape. Polarisation can occur spontaneously or be triggered by external signals, like gradients of signalling…

Analysis of PDEs · Mathematics 2013-01-18 Vincent Calvez , Nicolas Meunier , Nicolas Muller , Raphael Voituriez

The dynamics of chiral nuclei is investigated for the first time with the time-dependent and tilted axis cranking covariant density functional theories on a three-dimensional space lattice in a microscopic and self-consistent way. The…

Nuclear Theory · Physics 2022-02-08 Z. X. Ren , P. W. Zhao , J. Meng

The aim of these notes is to give a quick introduction to FK-percolation, focusing on certain recent results about the phase transition of the two dimensional model, namely its continuity or discontinuity depending on the cluster weight…

Probability · Mathematics 2025-03-04 Ioan Manolescu

The paper develops a new integral micromorphic elastic continuum model, which can describe dispersion properties of band-gap metamaterials, i.e., metamaterials that inhibit propagation of waves in a certain frequency range. The enrichment…

Applied Physics · Physics 2024-10-21 Michal Šmejkal , Milan Jirásek , Martin Horák

Electrical neural signalling typically takes place at the time-scale of milliseconds, and is typically modeled using the cable equation. This is a good approximation for processes when ionic concentrations vary little during the time course…

Cell Behavior · Quantitative Biology 2014-03-05 Geir Halnes , Ivar Østby , Klas H. Pettersen , Stig W. Omholt , Gaute T. Einevoll

Criticality is traditionally regarded as an unstable, fine-tuned fixed point of the renormalization group. We introduce an iterative bicolored percolation process in two dimensions and show that it can both preserve criticality and…

Statistical Mechanics · Physics 2026-03-25 Shuo Wei , Haoyu Liu , Xin Sun , Youjin Deng , Ming Li

A continuum electromechanical model is proposed to describe the membrane curvature induced by electrostatic interactions in a solvated protein-membrane system. The model couples the macroscopic strain energy of membrane and the…

Quantitative Methods · Quantitative Biology 2015-05-19 Y. C. Zhou , Benzhuo Lu , Alemayehu A. Gorfe

Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…

Biological Physics · Physics 2016-12-07 Bernhard Fichtl , Matthias F. Schneider

Recently, a simple non-interacting-electron model, combining local quantum tunneling via quantum point contacts and global classical percolation, has been introduced in order to describe the observed ``metal-insulator transition'' in two…

Mesoscale and Nanoscale Physics · Physics 2009-10-31 Yigal Meir