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Given a set of sequences, the distance between pairs of them helps us to find their similarity and derive structural relationship amongst them. For genomic sequences such measures make it possible to construct the evolution tree of…

Information Theory · Computer Science 2012-08-29 Sandeep Hosangadi

Many interesting machine learning problems are best posed by considering instances that are distributions, or sample sets drawn from distributions. Previous work devoted to machine learning tasks with distributional inputs has done so…

Machine Learning · Statistics 2021-01-15 Danica J. Sutherland , Junier B. Oliva , Barnabás Póczos , Jeff Schneider

The Genome Median Problem is an important problem in phylogenetic reconstruction under rearrangement models. It can be stated as follows: given three genomes, find a fourth that minimizes the sum of the pairwise rearrangement distances…

Quantitative Methods · Quantitative Biology 2013-08-02 João Paulo Pereira Zanetti , Priscila Biller , João Meidanis

Reconciling gene trees with a species tree is a fundamental problem to understand the evolution of gene families. Many existing approaches reconcile each gene tree independently. However, it is well-known that the evolution of gene families…

Populations and Evolution · Quantitative Biology 2018-06-12 Riccardo Dondi , Manuel Lafond , Celine Scornavacca

The normalized edit distance is one of the distances derived from the edit distance. It is useful in some applications because it takes into account the lengths of the two strings compared. The normalized edit distance is not defined in…

Neural and Evolutionary Computing · Computer Science 2013-12-09 Muhammad Marwan Muhammad Fuad

Insertion-deletion codes (insdel codes for short) are used for correcting synchronization errors in communications, and in other many interesting fields such as DNA storage, date analysis, race-track memory error correction and language…

Information Theory · Computer Science 2022-06-02 Qinqin Ji , Dabin Zheng , Hao Chen , Xiaoqiang Wang

Recent advances in generative modeling have led to an increased interest in the study of statistical divergences as means of model comparison. Commonly used evaluation methods, such as the Frechet Inception Distance (FID), correlate well…

Machine Learning · Statistics 2018-10-30 Mehdi S. M. Sajjadi , Olivier Bachem , Mario Lucic , Olivier Bousquet , Sylvain Gelly

The edit distance between strings classically assigns unit cost to every character insertion, deletion, and substitution, whereas the Hamming distance only allows substitutions. In many real-life scenarios, insertions and deletions…

Data Structures and Algorithms · Computer Science 2026-02-23 Elazar Goldenberg , Tomasz Kociumaka , Robert Krauthgamer , Barna Saha

Tandem duplication in DNA is the process of inserting a copy of a segment of DNA adjacent to the original position. Motivated by applications that store data in living organisms, Jain {\em et al.} (2016) proposed the study of codes that…

Combinatorics · Mathematics 2017-11-20 Yeow Meng Chee , Johan Chrisnata , Han Mao Kiah , Tuan Thanh Nguyen

Distance Geometry Problem (DGP) and Nonlinear Mapping (NLM) are two well established questions: Distance Geometry Problem is about finding a Euclidean realization of an incomplete set of distances in a Euclidean space, whereas Nonlinear…

Computational Geometry · Computer Science 2019-05-10 Alain Franc , Pierre Blanchard , Olivier Coulaud

Reconstructing ancestral gene orders is an important step towards understanding genome evolution. The Small Parsimony Problem (SPP) has been extensively studied in this regard. The problem aims at finding the gene orders at internal nodes…

Data Structures and Algorithms · Computer Science 2021-08-11 Daniel Doerr , Cedric Chauve

Imitation learning algorithms have been interpreted as variants of divergence minimization problems. The ability to compare occupancy measures between experts and learners is crucial in their effectiveness in learning from demonstrations.…

Machine Learning · Computer Science 2022-07-05 Georgios Papagiannis , Yunpeng Li

Graph Edit Distance (GED) is a widely used metric for measuring similarity between two graphs. Computing the optimal GED is NP-hard, leading to the development of various neural and non-neural heuristics. While neural methods have achieved…

Machine Learning · Computer Science 2025-05-06 Samidha Verma , Arushi Goyal , Ananya Mathur , Ankit Anand , Sayan Ranu

Learning scientific document representations can be substantially improved through contrastive learning objectives, where the challenge lies in creating positive and negative training samples that encode the desired similarity semantics.…

Computation and Language · Computer Science 2022-10-20 Malte Ostendorff , Nils Rethmeier , Isabelle Augenstein , Bela Gipp , Georg Rehm

Although recovering an Euclidean distance matrix from noisy observations is a common problem in practice, how well this could be done remains largely unknown. To fill in this void, we study a simple distance matrix estimate based upon the…

Machine Learning · Statistics 2014-09-18 Luwan Zhang , Grace Wahba , Ming Yuan

String edit distances have been used for decades in applications ranging from spelling correction and web search suggestions to DNA analysis. Most string edit distances are variations of the Levenshtein distance and consider only…

Genomics · Quantitative Biology 2022-05-12 Taylor Petty , Jan Hannig , Tunde I Huszar , Hari Iyer

Recently, due to the genomic sequence analysis in several types of cancer, the genomic data based on {\em copy number profiles} ({\em CNP} for short) are getting more and more popular. A CNP is a vector where each component is a…

Data Structures and Algorithms · Computer Science 2020-02-13 Manuel Lafond , Binhai Zhu , Peng Zou

Given a pair of strings, the problems of computing their Longest Common Subsequence and Edit Distance have been extensively studied for decades. For exact algorithms, LCS and Edit Distance (with character insertions and deletions) are…

Data Structures and Algorithms · Computer Science 2019-04-12 Aviad Rubinstein , Zhao Song

Kondo et al. (DS 2014) proposed methods for computing distances between unordered rooted trees by transforming an instance of the distance computing problem into an instance of the integer programming problem. They showed that the tree edit…

Data Structures and Algorithms · Computer Science 2017-06-13 Eunpyeong Hong , Yasuaki Kobayashi , Akihiro Yamamoto

We propose a new distance metric for DNA sequences, which can be defined on any evolutionary Markov model with infinitesimal generator matrix Q. That is the new metric can be defined under existing models such as Jukes-Cantor model,…

Populations and Evolution · Quantitative Biology 2009-02-12 Viswanath. C. Narayanan