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Multivariate mixed-type outcomes are difficult to model jointly, and additional complexity arises when both marginal effects and dependence structures vary with a covariate such as age or time. Existing approaches often impose restrictive…

Methodology · Statistics 2026-04-15 Yujin Jeong , Seonghyun Jeong

This article proposes a graphical model that handles mixed-type, multi-group data. The motivation for such a model originates from real-world observational data, which often contain groups of samples obtained under heterogeneous conditions…

Methodology · Statistics 2023-01-02 Sjoerd Hermes , Joost van Heerwaarden , Pariya Behrouzi

Learning the joint dependence of discrete variables is a fundamental problem in machine learning, with many applications including prediction, clustering and dimensionality reduction. More recently, the framework of copula modeling has…

Machine Learning · Statistics 2013-11-15 Alfredo Kalaitzis , Ricardo Silva

There is an extensive literature on methods for meta-analysis of diagnostic studies, but it mainly focuses on a single test. However, the better understanding of a particular disease has led to the development of multiple tests. A…

Methodology · Statistics 2020-10-19 Aristidis K. Nikoloulopoulos

Probability density estimation from observed data constitutes a central task in statistics. In this brief, we focus on the problem of estimating the copula density associated to any observed data, as it fully describes the dependence…

Machine Learning · Computer Science 2025-07-09 Nunzio A. Letizia , Nicola Novello , Andrea M. Tonello

Regular vine copulas can describe a wider array of dependency patterns than the multivariate Gaussian copula or the multivariate Student's t copula. This paper presents two contributions related to model selection of regular vine copulas.…

Statistics Theory · Mathematics 2015-12-04 Lutz Gruber , Claudia Czado

In this paper, we propose a regular vine copula based methodology for the fusion of correlated decisions. Regular vine copula is an extremely flexible and powerful graphical model to characterize complex dependence among multiple…

Signal Processing · Electrical Eng. & Systems 2019-03-27 Shan Zhang , Lakshmi Narasimhan Theagarajan , Sora Choi , Pramod K. Varshney

Copula-based models provide a great deal of flexibility in modelling multivariate distributions, allowing for the specifications of models for the marginal distributions separately from the dependence structure (copula) that links them to…

Methodology · Statistics 2021-09-09 Nicolás Kuschinski , Alejandro Jara

The original development of Shapley values for prediction explanation relied on the assumption that the features being described were independent. If the features in reality are dependent this may lead to incorrect explanations. Hence,…

Methodology · Statistics 2021-02-15 Kjersti Aas , Thomas Nagler , Martin Jullum , Anders Løland

Reconstructing gene regulatory networks from large-scale heterogeneous data is a key challenge in biology. In multi-omics data analysis, networks based on pairwise statistical association measures remain popular, as they are easy to build…

Methodology · Statistics 2025-06-11 Ekaterina Tomilina , Florence Jaffrézic , Gildas Mazo

Time-varying dependence is often modeled with dynamic correlations or Gaussian graphical models, but multivariate systems can change through tail behavior, asymmetry, or conditional structure even when correlations are nearly stable. We…

Machine Learning · Statistics 2026-05-08 Houman Safaai , Alessandro Marin Vargas

We propose and demonstrate a joint model of anatomical shapes, image features and clinical indicators for statistical shape modeling and medical image analysis. The key idea is to employ a copula model to separate the joint dependency…

Image and Video Processing · Electrical Eng. & Systems 2019-09-10 Bernhard Egger , Markus D. Schirmer , Florian Dubost , Marco J. Nardin , Natalia S. Rost , Polina Golland

We consider the problem of modeling the dependence among many time series. We build high dimensional time-varying copula models by combining pair-copula constructions (PCC) with stochastic autoregressive copula (SCAR) models to capture…

Methodology · Statistics 2012-02-10 Carlos Almeida , Claudia Czado , Hans Manner

Electronic health records (EHR) store hundreds of demographic and laboratory variables from large patient populations. Traditional statistical methods have limited capacity in processing mixed-type data (continuous, ordinal) and capturing…

Computation · Statistics 2026-04-10 Manar D. Samad , Yina Hou , Megan A. Witherow , Norou Diawara

This article extends the literature on copulas with discrete or continuous marginals to the case where some of the marginals are a mixture of discrete and continuous components. We do so by carefully defining the likelihood as the density…

Methodology · Statistics 2017-09-05 David Gunawan , Mohamad A. Khaled , Robert Kohn

Multivariate time series exhibit two types of dependence: across variables and across time points. Vine copulas are graphical models for the dependence and can conveniently capture both types of dependence in the same model. We derive the…

Methodology · Statistics 2022-03-16 Thomas Nagler , Daniel Krüger , Aleksey Min

We address an important yet challenging problem - modeling high-dimensional dependencies across multivariates such as financial indicators in heterogeneous markets. In reality, a market couples and influences others over time, and the…

Statistical Finance · Quantitative Finance 2023-05-16 Jia Xu , Longbing Cao

Handling highly dependent data is crucial in clinical trials, particularly in fields related to ophthalmology. Incorrectly specifying the dependency structure can lead to biased inferences. Traditionally, models rely on three fixed…

Methodology · Statistics 2025-09-30 Shuyi Liang , Takeshi Emura , Chang-Xing Ma , Yijing Xin , Xin-Wei Huang

In recent years, conditional copulas, that allow dependence between variables to vary according to the values of one or more covariates, have attracted increasing attention. In high dimension, vine copulas offer greater flexibility compared…

Methodology · Statistics 2021-09-24 Rosario Barone , Luciana Dalla Valle

As meta-analysis of multiple diagnostic tests impacts clinical decision making and patient health, there is growing interest in statistical models that synthesize evidence from studies comparing multiple diagnostic tests. To compare the…

Methodology · Statistics 2026-05-19 Aristidis K. Nikoloulopoulos