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Developing computational models of neural response is crucial for understanding sensory processing and neural computations. Current state-of-the-art neural network methods use temporal filters to handle temporal dependencies, resulting in…

Neurons and Cognition · Quantitative Biology 2023-12-21 Gehua Ma , Runhao Jiang , Rui Yan , Huajin Tang

This paper considers the problem of learning, from samples, the dependency structure of a system of linear stochastic differential equations, when some of the variables are latent. In particular, we observe the time evolution of some…

Machine Learning · Computer Science 2012-05-02 Ali Jalali , Sujay Sanghavi

We designed a model-based analysis to predict the occurrence of population patterns in distributed spiking activity. Using a maximum entropy principle with a Markovian assumption, we obtain a model that accounts for both spatial and…

Neurons and Cognition · Quantitative Biology 2009-11-13 Olivier Marre , Sami El Boustani , Yves Fregnac , Alain Destexhe

Many fMRI analyses examine functional connectivity, or statistical dependencies among remote brain regions. Yet popular methods for studying whole-brain functional connectivity often yield results that are difficult to interpret. Factor…

Methodology · Statistics 2024-09-24 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Most machine learning models for structured data encode the structural knowledge of a node by leveraging simple aggregation functions (in neural models, typically a weighted sum) of the information in the node's neighbourhood. Nevertheless,…

Machine Learning · Computer Science 2020-06-18 Daniele Castellana , Davide Bacciu

A major obstacle to understanding neural coding and computation is the fact that experimental recordings typically sample only a small fraction of the neurons in a circuit. Measured neural properties are skewed by interactions between…

Neurons and Cognition · Quantitative Biology 2025-04-01 Braden A. W. Brinkman , Fred Rieke , Eric Shea-Brown , Michael A. Buice

Statistical analysis of high-dimensional functional times series arises in various applications. Under this scenario, in addition to the intrinsic infinite-dimensionality of functional data, the number of functional variables can grow with…

Statistics Theory · Mathematics 2022-01-14 Qin Fang , Shaojun Guo , Xinghao Qiao

We propose a normative model for spatial representation in the hippocampal formation that combines optimality principles, such as maximizing coding range and spatial information per neuron, with an algebraic framework for computing in…

Neurons and Cognition · Quantitative Biology 2024-06-28 Christopher J. Kymn , Sonia Mazelet , Anthony Thomas , Denis Kleyko , E. Paxon Frady , Friedrich T. Sommer , Bruno A. Olshausen

Recent results in coupled or temporal graphical models offer schemes for estimating the relationship structure between features when the data come from related (but distinct) longitudinal sources. A novel application of these ideas is for…

Machine Learning · Statistics 2017-11-22 Ronak Mehta , Hyunwoo J. Kim , Shulei Wang , Sterling C. Johnson , Ming Yuan , Vikas Singh

In this paper, we propose a method for temporal segmentation of human repetitive actions based on frequency analysis of kinematic parameters, zero-velocity crossing detection, and adaptive k-means clustering. Since the human motion data may…

Computer Vision and Pattern Recognition · Computer Science 2015-12-15 Qifei Wang , Gregorij Kurillo , Ferda Ofli , Ruzena Bajcsy

We propose a flexible yet interpretable model for high-dimensional data with time-varying second order statistics, motivated and applied to functional neuroimaging data. Motivated by the neuroscience literature, we factorize the covariances…

Machine Learning · Statistics 2021-07-20 Katherine Tsai , Mladen Kolar , Oluwasanmi Koyejo

Urban analytics increasingly relies on AI-driven trajectory analysis, yet current approaches suffer from methodological fragmentation: trajectory learning captures movement patterns but ignores spatial context, while spatial embedding…

Machine Learning · Computer Science 2025-12-04 Stephen Law , Tao Yang , Nanjiang Chen , Xuhui Lin

Trial-to-trial variability of neural responses has been linked to important aspects of neural computation and is essential for understanding how neuronal populations respond. While current overdispersion models treat each neuron's gain as…

Quantitative Methods · Quantitative Biology 2026-05-11 Skyler Thomas , Brandon J. Zhu , Kathleen E. Cullen , Adam S. Charles

To maximize future rewards in this ever-changing world, animals must be able to discover the temporal structure of stimuli and then anticipate or act correctly at the right time. How the animals perceive, maintain, and use time intervals…

Neurons and Cognition · Quantitative Biology 2020-07-08 Zedong Bi , Changsong Zhou

The brain is organized in a modular way, serving multiple functionalities. This multiplicity requires that both positive (e.g. excitatory, phase-coherent) and negative (e.g. inhibitory, phase-opposing) interactions take place across brain…

Neurons and Cognition · Quantitative Biology 2019-07-29 Assaf Almog , Ori Roethler , Renate Buijink , Stephan Michel , Johanna H Meijer , Jos H. T. Rohling , Diego Garlaschelli

The matrix-variate normal distribution is a popular model for high-dimensional transposable data because it decomposes the dependence structure of the random matrix into the Kronecker product of two covariance matrices: one for each of the…

Methodology · Statistics 2014-11-11 Anestis Touloumis , John Marioni , Simon Tavaré

Understanding the evolving dependence between two clusters of multivariate signals is fundamental in neuroscience and other domains where sub-networks in a system interact dynamically over time. Despite the growing interest in multivariate…

Methodology · Statistics 2025-11-26 Haibo Wu , Marina I. Knight , Keiland W. Cooper , Norbert J. Fortin , Hernando Ombao

We propose a probabilistic framework for developing computational models of biological neural systems. In this framework, physiological recordings are viewed as discrete-time partial observations of an underlying continuous-time stochastic…

Neurons and Cognition · Quantitative Biology 2026-02-10 Ahmed ElGazzar , Marcel van Gerven

Spatial models for areal data are often constructed such that all pairs of adjacent regions are assumed to have near-identical spatial autocorrelation. In practice, data can exhibit dependence structures more complicated than can be…

Methodology · Statistics 2024-07-04 Michael F. Christensen , Peter D. Hoff

Understanding the neural implementation of complex human behaviors is one of the major goals in neuroscience. To this end, it is crucial to find a true representation of the neural data, which is challenging due to the high complexity of…

Machine Learning · Computer Science 2023-08-15 Cheol Jun Cho , Edward F. Chang , Gopala K. Anumanchipalli
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