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MRI analysis takes central position in brain tumor diagnosis and treatment, thus it's precise evaluation is crucially important. However, it's 3D nature imposes several challenges, so the analysis is often performed on 2D projections that…

Cell segmentation is a critical step for quantitative single-cell analysis in microscopy images. Existing cell segmentation methods are often tailored to specific modalities or require manual interventions to specify hyper-parameters in…

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Manual segmentation of hepatic metastases in ultrasound images acquired from patients suffering from pancreatic cancer is common practice. Semiautomatic measurements promising assistance in this process are often assessed using a small…

We propose a fully-automated method for accurate and robust detection and segmentation of potentially cancerous lesions found in the liver and in lymph nodes. The process is performed in three steps, including organ detection, lesion…

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Analysis of microscopy images can provide insight into many biological processes. One particularly challenging problem is cell nuclear segmentation in highly anisotropic and noisy 3D image data. Manually localizing and segmenting each and…

Instance segmentation of biological images is essential for studying object behaviors and properties. The challenges, such as clustering, occlusion, and adhesion problems of the objects, make instance segmentation a non-trivial task.…

Histopathological cancer diagnostics has become more complex, and the increasing number of biopsies is a challenge for most pathology laboratories. Thus, development of automatic methods for evaluation of histopathological cancer sections…

Prostate cancer is the most abundant cancer in men, with over 200,000 expected new cases and around 28,000 deaths in 2012 in the US alone. In this study, the segmentation results for the prostate central gland (PCG) in MR scans are…

Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only…

Segmenting a MRI images into homogeneous texture regions representing disparate tissue types is often a useful preprocessing step in the computer-assisted detection of breast cancer. That is why we proposed new algorithm to detect cancer in…

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Deep learning has quickly become the weapon of choice for brain lesion segmentation. However, few existing algorithms pre-configure any biological context of their chosen segmentation tissues, and instead rely on the neural network's…

Brain tumor diagnosis is a challenging task for clinicians in the modern world. Among the major reasons for cancer-related death is the brain tumor. Gliomas, a category of central nervous system (CNS) tumors, encompass diverse subregions.…

When applying automatic analysis of fluorescence or histopathological images of cells, it is necessary to partition, or de-clump, partially overlapping cell nuclei. In this work, I describe a method of partitioning partially overlapping…

Mandible bone segmentation from computed tomography (CT) scans is challenging due to mandible's structural irregularities, complex shape patterns, and lack of contrast in joints. Furthermore, connections of teeth to mandible and mandible to…

Characterization of breast lesions is an essential prerequisite to detect breast cancer in an early stage. Automatic segmentation makes this categorization method robust by freeing it from subjectivity and human error. Both spectral and…

Organ segmentation is a prerequisite for a computer-aided diagnosis (CAD) system to detect pathologies and perform quantitative analysis. For anatomically high-variability abdominal organs such as the pancreas, previous segmentation works…

Automated detection and segmentation of pulmonary nodules on lung computed tomography (CT) scans can facilitate early lung cancer diagnosis. Existing supervised approaches for automated nodule segmentation on CT scans require voxel-based…