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Learning spatial-temporal correspondences in cardiac motion from images is important for understanding the underlying dynamics of cardiac anatomical structures. Many methods explicitly impose smoothness constraints such as the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-05 Xiaoran Zhang , Chenyu You , Shawn Ahn , Juntang Zhuang , Lawrence Staib , James Duncan

Atrioventricular valve regurgitation is a significant cause of morbidity and mortality in patients with acquired and congenital cardiac valve disease. Image-derived computational modeling of atrioventricular valves has advanced…

Tissues and Organs · Quantitative Biology 2022-02-01 Wensi Wu , Stephen Ching , Steve A. Maas , Andras Lasso , Patricia Sabin , Jeffrey A. Weiss , Matthew A. Jolley

Intra-cardiac Echocardiography (ICE) plays a critical role in Electrophysiology (EP) and Structural Heart Disease (SHD) interventions by providing real-time visualization of intracardiac structures. However, maintaining continuous…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Jaeyoung Huh , Ankur Kapoor , Young-Ho Kim

Computational fluid dynamics (CFD) models of blood flow in the left ventricle (LV) and aorta are important tools for analyzing the mechanistic links between myocardial deformation and flow patterns. Typically, the use of image-based…

Virtual interventions enable the physics-based simulation of device deployment within coronary arteries. This framework allows for counterfactual reasoning by deploying the same device in different arterial anatomies. However, current…

Image and Video Processing · Electrical Eng. & Systems 2025-11-26 Karim Kadry , Shreya Gupta , Jonas Sogbadji , Michiel Schaap , Kersten Petersen , Takuya Mizukami , Carlos Collet , Farhad R. Nezami , Elazer R. Edelman

Embolization, stroke, ischaemic lesion, and perforation remain significant concerns in endovascular interventions. Intravascular sensing of tool interaction with the arteries is advantageous to minimize such complications and enhance…

Robotics · Computer Science 2021-02-16 Masoud Razban , Javad Dargahi , Benoit Boulet

Purpose: To develop and evaluate a dynamic, image-derived patient-specific physical simulation platform for the assessment of left atrioventricular valve (LAVV) repair strategies in pediatric patients with repaired atrioventricular canal…

Spatial patterns of elevated wall shear stress and pressure due to blood flow past aortic stenosis (AS) are studied using GPU-accelerated patient-specific computational fluid dynamics. Three cases of moderate AS, one with a dilated…

Fluid Dynamics · Physics 2022-12-13 Hadi Zolfaghari , Mervyn Andiapen , Andreas Baumbach , Anthony Mathur , Rich R. Kerswell

Robotic-assisted tracheal intubation requires the robot to distinguish anatomical features like an experienced physician using deep-learning techniques. However, real datasets of oropharyngeal organs are limited due to patient privacy…

Image and Video Processing · Electrical Eng. & Systems 2023-07-29 Guankun Wang , Tian-Ao Ren , Jiewen Lai , Long Bai , Hongliang Ren

Coronary artery bypass grafts (CABG) surgery is an invasive procedure performed to circumvent partial or complete blood flow blockage in coronary artery disease (CAD). In this work, we apply a numerical optimal flow control model to…

Numerical Analysis · Mathematics 2023-08-08 Zakia Zainib , Francesco Ballarin , Stephen Fremes , Piero Triverio , Laura Jiménez-Juan , Gianluigi Rozza

We present a robust immersed boundary (IB) method for high density ratio multiphase flows that is capable of modeling complex wave-structure interaction (WSI) problems arising in marine and coastal engineering applications. The IB/WSI…

Fluid Dynamics · Physics 2019-09-04 Nishant Nangia , Neelesh A. Patankar , Amneet Pal Singh Bhalla

Advances in three-dimensional imaging provide the ability to construct and analyze finite element (FE) models to evaluate the biomechanical behavior and function of atrioventricular valves. However, while obtaining patient-specific valve…

Representing large-scale motions and topological changes in the finite volume (FV) framework, while at the same time preserving the accuracy of the numerical solution, is difficult. In this paper, we present a robust, highly efficient…

Fluid Dynamics · Physics 2017-11-17 Georgios K. Karpouzas , Eugene De Villiers

Deformable elastic bodies in viscous and viscoelastic media constitute a large portion of synthetic and biological complex fluids. We present a parallelized 3D-simulation methodology which fully resolves the momentum balance in the solid…

Computational Physics · Physics 2019-03-11 Amir Saadat , Chris J. Guido , Gianluca Iaccarino , Eric S. G. Shaqfeh

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Anatomical landmark localization is gaining attention to ease the burden on physicians. Focusing on aortic root landmark localization, the three hinge points of the aortic valve can reduce the burden by automatically determining the valve…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Tsuyoshi Ishizone , Masaki Miyasaka , Sae Ochi , Norio Tada , Kazuyuki Nakamura

This review focuses on the computerized modeling of the electrophysiology of the human atria, emphasizing the simulation of common arrhythmias such as atrial flutter (AFlut) and atrial fibrillation (AFib). Which components of the model are…

Computational Physics · Physics 2025-05-30 Olaf Dössel , Axel Loewe

With the advent of wearable Internet of Things (IoT) devices, remote patient monitoring (RPM) emerged as a promising solution for managing heart failure. However, the heart rate can fluctuate significantly due to various factors, and…

Machine Learning · Computer Science 2025-08-26 Andrei Mateescu , Ioana Hadarau , Ionut Anghel , Tudor Cioara , Ovidiu Anchidin , Ancuta Nemes

The Immersed Boundary (IB) method of Peskin (J. Comput. Phys., 1977) is useful for problems involving fluid-structure interactions or complex geometries. By making use of a regular Cartesian grid that is independent of the geometry, the IB…

Numerical Analysis · Mathematics 2024-02-06 Brittany J. Leathers , Robert D. Guy

Cardiovascular disease arises from interactions between inherited risk, molecular programmes, and tissue-scale remodelling that are observed clinically through imaging. Health systems now routinely generate large volumes of cardiac MRI, CT…

Quantitative Methods · Quantitative Biology 2026-01-14 Minh H. N. Le , Tuan Vinh , Thanh-Huy Nguyen , Tao Li , Bao Quang Gia Le , Han H. Huynh , Monika Raj , Carl Yang , Min Xu , Nguyen Quoc Khanh Le