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Computational modelling of diffusion in heterogeneous media is prohibitively expensive for problems with fine-scale heterogeneities. A common strategy for resolving this issue is to decompose the domain into a number of non-overlapping…

Computational Physics · Physics 2021-08-26 Nathan G. March , Elliot J. Carr , Ian W. Turner

Coarse-grained (CG) models provide an effective route to reducing the complexity of molecular simulations (MD), but conventional approaches depend heavily on long all-atom MD trajectories to adequately sample configurational space. This…

Chemical Physics · Physics 2025-10-28 Maximilian Stupp , P. S. Koutsourelakis

Certain sequences of peptoid polymers (synthetic analogs of peptides) assemble into bilayer nanosheets via a nonequilibrium assembly pathway of adsorption, compression, and collapse at an air-water interface. As with other large-scale…

Biological Physics · Physics 2014-10-01 Thomas K. Haxton , Ranjan V. Mannige , Ronald N. Zuckermann , Stephen Whitelam

Big data often has emergent structure that exists at multiple levels of abstraction, which are useful for characterizing complex interactions and dynamics of the observations. Here, we consider multiple levels of abstraction via a…

Increasing the efficiency of materials design and discovery remains a significant challenge, especially given the prohibitively large size of chemical compound space. The use of a chemically transferable coarse-grained model enables…

Chemical Physics · Physics 2020-01-08 Kiran H. Kanekal , Tristan Bereau

The dynamical cluster approximation (DCA) and its DCA$^+$ extension use coarse-graining of the momentum space to reduce the complexity of quantum many-body problems, thereby mapping the bulk lattice to a cluster embedded in a dynamical…

Strongly Correlated Electrons · Physics 2016-05-04 P. Staar , M. Jiang , U. R. Hähner , T. C. S. Schulthess , T. A. Maier

The promise of machine learning has been explored in a variety of scientific disciplines in the last few years, however, its application on first-principles based computationally expensive tools is still in nascent stage. Even with the…

Data Analysis, Statistics and Probability · Physics 2019-07-16 Prashant Kumar , Kushal Sinha , Nandkishor Nere , Yujin Shin , Raimundo Ho , Ahmad Sheikh , Laurie Mlinar

In Computational Fluid Dynamics (CFD), coarse mesh simulations offer computational efficiency but often lack precision. Applying conventional super-resolution to these simulations poses a significant challenge due to the fundamental…

Due to the increasing demand for high performance and cost reduction within the framework of complex system design, numerical optimization of computationally costly problems is an increasingly popular topic in most engineering fields. In…

Optimization and Control · Mathematics 2018-06-12 Julien Pelamatti , Loïc Brevault , Mathieu Balesdent , El-Ghazali Talbi , Yannick Guerin

We study an element agglomeration coarsening strategy that requires data redistribution at coarse levels when the number of coarse elements becomes smaller than the used computational units (cores). The overall procedure generates coarse…

Numerical Analysis · Mathematics 2025-12-01 Hillary R. Fairbanks , Delyan Z. Kalchev , Chak Shing Lee , Panayot S. Vassilevski

Recent progress in deep learning has been driven by increasingly larger models. However, their computational and energy demands have grown proportionally, creating significant barriers to their deployment and to a wider adoption of deep…

Machine Learning · Computer Science 2025-09-16 Pedro Savarese

The presence of surface defects (roughness, surface imperfections, profiles, etc.) in a contact inevitably leads to the modification of its local properties, such as the coefficient of friction. In railway wheelsets, this surface condition…

Classical Physics · Physics 2025-10-03 Victor Lalleman , Pierre Gosselet , Cédric Hubert , Stéphane Salengro , Vincent Magnier

We present an approach for the inclusion of non-spherical constituents in high-resolution N-body discrete element method (DEM) simulations. We use aggregates composed of bonded spheres to model non-spherical components. Though the method…

Earth and Planetary Astrophysics · Physics 2023-11-21 Julian C. Marohnic , Joseph V. DeMartini , Derek C. Richardson , Yun Zhang , Kevin J. Walsh

Sheared granular layers undergoing stick slip behavior are broadly employed to study the physics and dynamics of earthquakes. Here, a two dimensional implementation of the combined finite discrete element method (FDEM), which merges the…

We study dendritic microstructure evolution using an adaptive grid, finite element method applied to a phase-field model. The computational complexity of our algorithm, per unit time, scales linearly with system size, rather than the…

Materials Science · Physics 2009-10-30 Nikolas Provatas , Nigel Goldenfeld , Jonathan Dantzig

Incorporating atomistic and molecular information into models of cellular behaviour is challenging because of a vast separation of spatial and temporal scales between processes happening at the atomic and cellular levels. Multiscale or…

Computational Physics · Physics 2019-08-28 Radek Erban

Molecular discovery within the vast chemical space remains a significant challenge due to the immense number of possible molecules and limited scalability of conventional screening methods. To approach chemical space exploration more…

Chemical Physics · Physics 2025-07-16 Luis J. Walter , Tristan Bereau

Free surface and granular fluid mechanics problems combine the challenges of fluid dynamics with aspects of granular behaviour. This type of problem is particularly relevant in contexts such as the flow of sediments in rivers, the movement…

Computational Engineering, Finance, and Science · Computer Science 2025-01-07 Thomas Leyssens , Michel Henry , Jonathan Lambrechts , Vincent Legat , Jean-François Remacle

In this paper, we show how kernel-based models for the Koopman generator -- the gEDMD method -- can be used to identify coarse-grained dynamics on reduced variables, which retain the slowest transition timescales of the original dynamics.…

Computational Physics · Physics 2025-03-26 Vahid Nateghi , Feliks Nüske

The idea of using fragment embedding to circumvent the high computational scaling of accurate electronic structure methods while retaining high accuracy has been a long-standing goal for quantum chemists. Traditional fragment embedding…

Chemical Physics · Physics 2022-10-11 Hong-Zhou Ye , Matthew Welborn , Nathan D. Ricke , Troy Van Voorhis
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