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Cell state discovery is crucial for understanding biological systems and enhancing medical outcomes. A key aspect of this process is identifying distinct biomarkers that define specific cell states. However, difficulties arise from the…

Human-Computer Interaction · Computer Science 2025-12-19 Rui Sheng , Zelin Zang , Jiachen Wang , Yan Luo , Zixin Chen , Yan Zhou , Shaolun Ruan , Huamin Qu

Studying cell morphology changes in time is critical to understanding cell migration mechanisms. In this work, we present a deep learning-based workflow to segment cancer cells embedded in 3D collagen matrices and imaged with phase-contrast…

Computer Vision and Pattern Recognition · Computer Science 2021-12-17 Estibaliz Gómez-de-Mariscal , Hasini Jayatilaka , Özgün Çiçek , Thomas Brox , Denis Wirtz , Arrate Muñoz-Barrutia

In microscopy image cell segmentation, it is common to train a deep neural network on source data, containing different types of microscopy images, and then fine-tune it using a support set comprising a few randomly selected and annotated…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Youssef Dawoud , Arij Bouazizi , Katharina Ernst , Gustavo Carneiro , Vasileios Belagiannis

We propose an automatic preprocessing and ensemble learning for segmentation of cell images with low quality. It is difficult to capture cells with strong light. Therefore, the microscopic images of cells tend to have low image quality but…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Sota Kato , Kazuhiro Hotta

Modeling tap or click sequences of users on a mobile device can improve our understandings of interaction behavior and offers opportunities for UI optimization by recommending next element the user might want to click on. We analyzed a…

Machine Learning · Computer Science 2021-08-12 Xin Zhou , Yang Li

Advanced image segmentation and processing tools present an opportunity to study cell processes and their dynamics. However, image analysis is often routine and time-consuming. Nowadays, alternative data-driven approaches using deep…

Automated and semi-automated techniques in biomedical electron microscopy (EM) enable the acquisition of large datasets at a high rate. Segmentation methods are therefore essential to analyze and interpret these large volumes of data, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Anusha Aswath , Ahmad Alsahaf , Ben N. G. Giepmans , George Azzopardi

Cell image classification methods are currently being used in numerous applications in cell biology and medicine. Applications include understanding the effects of genes and drugs in screening experiments, understanding the role and…

Quantitative Methods · Quantitative Biology 2022-03-04 Mohammad Shifat-E-Rabbi , Xuwang Yin , Cailey Elizabeth Fitzgerald , Gustavo K. Rohde

Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Huaqian Wu , Clara Brémond-Martin , Kévin Bouaou , Cédric Clouchoux

Identification of different neuronal cell types is critical for understanding their contribution to brain functions. Yet, automated and reliable classification of neurons remains a challenge, primarily because of their biological…

Neural and Evolutionary Computing · Computer Science 2020-09-29 Eirini Troullinou , Grigorios Tsagkatakis , Spyridon Chavlis , Gergely Turi , Wen-Ke Li , Attila Losonczy , Panagiotis Tsakalides , Panayiota Poirazi

A new Bayesian state and parameter learning algorithm for multiple target tracking (MTT) models with image observations is proposed. Specifically, a Markov chain Monte Carlo algorithm is designed to sample from the posterior distribution of…

Applications · Statistics 2016-03-18 Lan Jiang , Sumeetpal S. Singh

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Avelino Javer , Jens Rittscher

Tracking microrobots is challenging, considering their minute size and high speed. As the field progresses towards developing microrobots for biomedical applications and conducting mechanistic studies in physiologically relevant media…

Computer Vision and Pattern Recognition · Computer Science 2023-10-17 Medha Sawhney , Bhas Karmarkar , Eric J. Leaman , Arka Daw , Anuj Karpatne , Bahareh Behkam

In this thesis, we propose a pioneering work on sparse keypoints tracking across images using transformer networks. While deep learning-based keypoints matching have been widely investigated using graph neural networks - and more recently…

Computer Vision and Pattern Recognition · Computer Science 2022-03-25 Oleksii Nasypanyi , Francois Rameau

A key challenge in the development of materials for the next generation of solar cells, sensors and transistors is linking macroscopic device performance to underlying microscopic properties. For years, fabrication of devices has been…

Bio-inspired optimization (including Evolutionary Computation and Swarm Intelligence) is a growing research topic with many competitive bio-inspired algorithms being proposed every year. In such an active area, preparing a successful…

Neural and Evolutionary Computing · Computer Science 2024-10-07 Antonio LaTorre , Daniel Molina , Eneko Osaba , Javier Del Ser , Francisco Herrera

Despite significant advances in particle imaging technologies over the past two decades, few advances have been made in particle tracking, i.e. linking individual particle positions across time series data. The state-of-the-art tracking…

Soft Condensed Matter · Physics 2022-01-25 Ella M. King , Zizhao Wang , David A. Weitz , Frans Spaepen , Michael P. Brenner

Accurate segmentation of live cell images has broad applications in clinical and research contexts. Deep learning methods have been able to perform cell segmentations with high accuracy; however developing machine learning models to do this…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Mayur Bhandary , J. Patricio Reyes , Eylul Ertay , Aman Panda

Adapting large pre-trained foundation models, e.g., SAM, for medical image segmentation remains a significant challenge. A crucial step involves the formulation of a series of specialized prompts that incorporate specific clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Xiuqi Zheng , Yuhang Zhang , Haoran Zhang , Hongrui Liang , Xueqi Bao , Zhuqing Jiang , Qicheng Lao

The mother machine is a popular microfluidic device that allows long-term time-lapse imaging of thousands of cells in parallel by microscopy. It has become a valuable tool for single-cell level quantitative analysis and characterization of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-22 Jean Ollion , Charles Ollion