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Several animal species are considered to exhibit what is called negligible senescence, i.e. they do not show signs of functional decline or any increase of mortality with age, and do not have measurable reductions in reproductive capacity…

Molecular Networks · Quantitative Biology 2015-10-15 Valeria Kogan , Ivan Molodtcov , Leonid I. Menshikov , Robert J. Shmookler Reis , Peter Fedichev

Modeling how individuals evolve over time is a fundamental problem in the natural and social sciences. However, existing datasets are often cross-sectional with each individual observed only once, making it impossible to apply traditional…

Machine Learning · Computer Science 2019-03-06 Emma Pierson , Pang Wei Koh , Tatsunori Hashimoto , Daphne Koller , Jure Leskovec , Nicholas Eriksson , Percy Liang

We investigate the low-temperature dynamics of a simple stochastic model, introduced recently in the context of the physics of glasses. The slowest characteristic time at equilibrium diverges exponentially at low temperature. On smaller…

Statistical Mechanics · Physics 2009-10-30 C Godreche , J M Luck

Widespread interest in non-destructive biomarkers of aging has led to a curse of plenty: a multitude of biological ages that each proffers a 'true' health-adjusted age of an individual. While each measure provides salient information on the…

Quantitative Methods · Quantitative Biology 2024-01-23 Glen Pridham , Andrew D. Rutenberg

Periodic forcing of nonlinear oscillators leads to a large number of dynamic behaviors. The coupling of the cell-cycle to the circadian clock provides a biological realization of such forcing. Using high throughput single-cell microscopy,…

Emerging empirical and theoretical thinking about human aging places considerable value upon the role of the environment as a major factor which can promote prolonged healthy longevity. Our contemporary, information-rich environment is…

Other Quantitative Biology · Quantitative Biology 2014-07-24 Marios Kyriazis

We present a nonlinear stochastic model of the human gait control system in a variety of gait regimes. The stride interval time series in normal human gait is characterized by slightly multifractal fluctuations. The fractal nature of the…

Statistical Mechanics · Physics 2009-11-07 Bruce J. West , Nicola Scafetta

We study and compare equilibrium and aging dynamics on both sides of the ideal glass transition temperature $T_{MCT}$. In the context of a mean field model, we observe that all dynamical behaviors are determined by the energy distance…

Disordered Systems and Neural Networks · Physics 2009-10-06 Alexandre Lefèvre

Frailty is a geriatric syndrome associated with the lack of physiological reserve and consequent adverse outcomes (therapy complications and death) in older adults. Recent research has shown associations between heart rate (HR) dynamics (HR…

Quantitative Methods · Quantitative Biology 2023-03-27 Patricio Arrué , Kaveh Laksari , Nima Toosizadeh

Dissipative environments are ubiquitous in nature, from microscopic swimmers in low-Reynolds-number fluids to macroscopic animals in frictional media. In this study, motivated by various behaviours of {\it Caenorhabditis elegans} during…

Adaptation and Self-Organizing Systems · Physics 2025-04-15 Kenta Ishimoto , Clément Moreau , Johann Herault

Growth patterns generated by filamentous organisms (e.g. actinomycetes and fungi) involve spatial and temporal dynamics at different length scales. Several mathematical models have been proposed in the last thirty years to address these…

Populations and Evolution · Quantitative Biology 2007-05-23 Michele Bezzi , Andrea Ciliberto

Granular materials densify under repeated mechanical perturbations, a nonequilibrium dynamics that underlies many natural and industrial processes. Because granular relaxation is governed by frictional contacts and energy dissipation, this…

Soft Condensed Matter · Physics 2025-10-20 Ye Yuan , Walter Kob , Hajime Tanaka

The relationship between physiological systems and modern electromechanical technologies is fast becoming intimate with high degrees of complex interaction. It can be argued that muscular function, limb movements, and touch perception serve…

Human-Computer Interaction · Computer Science 2012-03-15 Bradly Alicea

We adapt the non-linear $\sigma$ model to study the nonequilibrium critical dynamics of O(n) symmetric ferromagnetic system. Using the renormalization group analysis in $d=2+\epsilon$ dimensions we investigate the pure relaxation of the…

Statistical Mechanics · Physics 2009-11-11 Andrei A. Fedorenko , Steffen Trimper

Biological circuits such as neural or gene regulation networks use internal states to map sensory input to an adaptive repertoire of behavior. Characterizing this mapping is a major challenge for systems biology, and though experiments that…

Neurons and Cognition · Quantitative Biology 2022-10-12 Edward D. Lee , Xiaowen Chen , Bryan C. Daniels

The study of human dynamics has attracted much interest from many fields recently. In this paper, the fractal characteristic of human behaviors is investigated from the perspective of time series constructed with the amount of library…

Physics and Society · Physics 2015-05-20 Chao Fan , Jin-Li Guo , Yi-Long Zha

We have studied the effect of temperature on aging dynamics of laponite suspensions by carrying out the rheological oscillatory and creep experiments. We observed that at higher temperatures the mechanism responsible for aging became faster…

Soft Condensed Matter · Physics 2010-01-26 Varun Awasthi , Yogesh M Joshi

We study biological evolution on a random fitness landscape where correlations are introduced through a linear fitness gradient of strength $c$. When selection is strong and mutations rare the dynamics is a directed uphill walk that…

Populations and Evolution · Quantitative Biology 2015-04-16 Su-Chan Park , Ivan G. Szendro , Johannes Neidhart , Joachim Krug

The swimming behaviour of microorganisms can be strongly influenced by the rheology of their fluid environment. In this manuscript, we experimentally investigate the effects of shear-thinning viscosity on the swimming behaviour of an…

Fluid Dynamics · Physics 2015-06-22 David A. Gagnon , Nathan C. Keim , Paulo E. Arratia

Structured populations are ubiquitous across the biological sciences. Mathematical models of these populations allow us to understand how individual physiological traits drive the overall dynamics in aggregate. For example, linear age- or…

Analysis of PDEs · Mathematics 2022-04-25 Sabina L. Altus , Jeffrey C. Cameron , David M. Bortz
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