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The mean first passage time (MFPT) for a Brownian particle to reach a small target in cellular microdomains is a key parameter for chemical activation. Although asymptotic estimations of the MFPT are available for various geometries, these…

Neurons and Cognition · Quantitative Biology 2015-03-19 Juergen Reingruber , David Holcman

Questions of flux regulation in biological cells raise renewed interest in the narrow escape problem. The often inadequate expansions of the narrow escape time are due to a not so well known fact that the boundary singularity of Green's…

Mathematical Physics · Physics 2009-11-13 A. Singer , Z. Schuss , D. Holcman

This paper is concerned with uniqueness, phase retrieval and shape reconstruction methods for solving inverse electromagnetic source scattering problems with multi-frequency sparse phased or phaseless far field data. With the phased data,…

Analysis of PDEs · Mathematics 2019-06-07 Xia Ji , Xiaodong Liu

Brownian diffusion subject to stochastic resetting to a fixed position has been widely studied for applications to random search processes. In an unbounded domain, the mean first-passage time at a target site can be minimized for a…

Statistical Mechanics · Physics 2025-10-08 Pedro Julián-Salgado , Leonardo Dagdug , Denis Boyer

Locating the source that triggers a dynamical process is a fundamental but challenging problem in complex networks, ranging from epidemic spreading in society and on the Internet to cancer metastasis in the human body. An accurate…

Physics and Society · Physics 2016-11-15 Zhesi Shen , Shinan Cao , Wen-Xu Wang , Zengru Di , H. Eugene Stanley

When a piece of malicious information becomes rampant in an information diffusion network, can we identify the source node that originally introduced the piece into the network and infer the time when it initiated this? Being able to do so…

Social and Information Networks · Computer Science 2015-01-28 Mehrdad Farajtabar , Manuel Gomez-Rodriguez , Nan Du , Mohammad Zamani , Hongyuan Zha , Le Song

Learning dynamical systems from sparse observations is critical in numerous fields, including biology, finance, and physics. Even if tackling such problems is standard in general information fusion, it remains challenging for contemporary…

Machine Learning · Computer Science 2024-06-04 Ella Tamir , Arno Solin

We study the narrow escape problem in the disk, which consists in identifying the first exit time and first exit point distribution of a Brownian particle from the ball in dimension 2, with reflecting boundary conditions except on small…

Analysis of PDEs · Mathematics 2024-04-09 Tony Lelièvre , Mohamad Rachid , Gabriel Stoltz

We apply macroscopic fluctuation theory to study the diffusion of a tracer in a one-dimensional interacting particle system with excluded mutual passage, known as single-file diffusion. In the case of Brownian point particles with hard-core…

Statistical Mechanics · Physics 2014-11-18 P. L. Krapivsky , Kirone Mallick , Tridib Sadhu

Active particles self-propel themselves with a stochastically evolving velocity, generating a persistent motion leading to a non-diffusive behavior of the position distribution. Nevertheless, an effective diffusive behavior emerges at times…

Statistical Mechanics · Physics 2022-09-14 Ion Santra , Urna Basu , Sanjib Sabhapandit

This paper introduces a multi-frequency factorization method for imaging a time-dependent source, specifically to recover its spatial support and the associated excitation instants. Using far-field data from two opposite directions, we…

Numerical Analysis · Mathematics 2026-04-28 Guanqiu Ma , Hongxia Guo , Guanghui Hu

In this paper, we investigate the problem of source recovery in a dynamical system utilizing space-time samples. This is a specific issue within the broader field of dynamical sampling, which involves collecting samples from solutions to a…

Dynamical Systems · Mathematics 2023-08-04 Akram Aldroubi , Rocio Diaz Martin , Ivan Medri

Determining the positions of neurons in an extracellular recording is useful for investigating functional properties of the underlying neural circuitry. In this work, we present a Bayesian modelling approach for localizing the source of…

Neurons and Cognition · Quantitative Biology 2022-01-28 Cole L. Hurwitz , Kai Xu , Akash Srivastava , Alessio P. Buccino , Matthias H. Hennig

This paper is concerned with a direct sampling method for imaging the support of a frequency-dependent source term embedded in a homogeneous and isotropic medium. The source term is given by the Fourier transform of a time-dependent source…

Numerical Analysis · Mathematics 2022-12-12 Hongxia Guo , Guanghui Hu , Mengjie Zhao

Spectroastrometry is a technique which has the potential to resolve flux distributions on scales of milliarcseconds. In this study, we examine the application of spectroastrometry to binary point sources which are spatially unresolved due…

Astrophysics · Physics 2009-11-10 John M. Porter , Rene D. Oudmaijer , Debbie Baines

Consider the model where nodes are initially distributed as a Poisson point process with intensity $\lambda$ over $\mathbb{R}^d$ and are moving in continuous time according to independent Brownian motions. We assume that nodes are capable…

Probability · Mathematics 2015-09-10 Alexandre Stauffer

Identifying the drift and diffusion of an SDE from its population dynamics is a notoriously challenging task. Researchers in machine learning and single-cell biology have only been able to prove a partial identifiability result: for…

Generative models on discrete state-spaces have a wide range of potential applications, particularly in the domain of natural sciences. In continuous state-spaces, controllable and flexible generation of samples with desired properties has…

Machine Learning · Computer Science 2025-03-27 Hunter Nisonoff , Junhao Xiong , Stephan Allenspach , Jennifer Listgarten

Despite the widespread use of gradient-based algorithms for optimizing high-dimensional non-convex functions, understanding their ability of finding good minima instead of being trapped in spurious ones remains to a large extent an open…

We develop a formally exact technique for obtaining steady-state distributions of non-interacting active Brownian particles in a variety of systems. Our technique draws on results from the theory of two-way diffusion equations to solve the…

Soft Condensed Matter · Physics 2017-04-06 Caleb G. Wagner , Michael F. Hagan , Aparna Baskaran