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Recent Artificial Intelligence (AI) models have matched or exceeded human experts in several benchmarks of biomedical task performance, but surgical benchmarks in particular are often missing from prominent medical benchmark suites. Since…

Artificial intelligence (AI) is rapidly advancing in healthcare, enhancing the efficiency and effectiveness of services across various specialties, including cardiology, ophthalmology, dermatology, emergency medicine, etc. AI applications…

The majority of response-adaptive randomisation (RAR) designs in the literature rely on efficacy data to guide dynamic patient allocation. However, their applicability becomes limited in settings where efficacy outcomes, such as survival,…

Methodology · Statistics 2026-02-23 Maria Vittoria Chiaruttini , Lukas Pin , Sofia S. Villar

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

In the current era, people and society have grown increasingly reliant on artificial intelligence (AI) technologies. AI has the potential to drive us towards a future in which all of humanity flourishes. It also comes with substantial risks…

Computers and Society · Computer Science 2021-08-24 Lu Cheng , Kush R. Varshney , Huan Liu

Although AI holds promise for improving human decision making in societally critical domains, it remains an open question how human-AI teams can reliably outperform AI alone and human alone in challenging prediction tasks (also known as…

Artificial Intelligence · Computer Science 2021-10-07 Han Liu , Vivian Lai , Chenhao Tan

Despite variations in architecture and pretraining strategies, recent studies indicate that large-scale AI models often converge toward similar internal representations that also align with neural activity. We propose that scale-invariance,…

Neurons and Cognition · Quantitative Biology 2025-06-17 Junjie Yu , Wenxiao Ma , Jianyu Zhang , Haotian Deng , Zihan Deng , Yi Guo , Quanying Liu

There has been significant attention given to developing data-driven methods for tailoring patient care based on individual patient characteristics. Dynamic treatment regimes formalize this through a sequence of decision rules that map…

Methodology · Statistics 2022-02-22 Eric J. Rose , Erica E. M. Moodie , Susan Shortreed

The integration of artificial intelligence (AI) into medical diagnostic workflows requires robust and consistent evaluation methods to ensure reliability, clinical relevance, and the inherent variability in expert judgments. Traditional…

Machine Learning (ML) and Artificial Intelligence (AI) are powering the applications we use, the decisions we make, and the decisions made about us. We have seen numerous examples of non-equitable outcomes, from facial recognition…

Computers and Society · Computer Science 2023-11-21 Sharon Ferguson , Katherine Mao , James Magarian , Alison Olechowski

The implementation of Artificial Intelligence (AI) in the healthcare industry has garnered considerable attention, attributable to its prospective enhancement of clinical outcomes, expansion of access to superior healthcare, cost reduction,…

Computation and Language · Computer Science 2024-08-23 Arindam Sett , Somaye Hashemifar , Mrunal Yadav , Yogesh Pandit , Mohsen Hejrati

Clinical trials are pivotal for developing new medical treatments but typically carry risks such as patient mortality and enrollment failure that waste immense efforts spanning over a decade. Applying artificial intelligence (AI) to predict…

Randomized controlled trials (RCTs) are increasingly prevalent in education research, and are often regarded as a gold standard of causal inference. Two main virtues of randomized experiments are that they (1) do not suffer from…

Tasks requiring deductive reasoning, especially those involving multiple steps, often demand adaptive strategies such as intermediate generation of rationales or programs, as no single approach is universally optimal. While Language Models…

Artificial Intelligence · Computer Science 2024-10-22 Rongxing Liu , Kumar Shridhar , Manish Prajapat , Patrick Xia , Mrinmaya Sachan

In human-AI decision making, designing AI that complements human expertise has been a natural strategy to enhance human-AI collaboration, yet it often comes at the cost of decreased AI performance in areas of human strengths. This can…

Artificial Intelligence · Computer Science 2026-02-24 Hasan Amin , Ming Yin , Rajiv Khanna

Dynamic treatment regimes (DTRs) are sequences of decision rules to guide treatment assignments in response to a patient's evolving, time-varying disease status. Sequential multiple assignment randomized trials (SMARTs) are considered the…

Methodology · Statistics 2026-04-29 Xinru Wang , Meghna Bose , Bibhas Chakraborty , Robert Mahar

Multiple instance data are sets or multi-sets of unordered elements. Using metrics or distances for sets, we propose an approach to several multiple instance learning tasks, such as clustering (unsupervised learning), classification…

Machine Learning · Computer Science 2017-03-28 Quang N. Tran , Ba-Ngu Vo , Dinh Phung , Ba-Tuong Vo , Thuong Nguyen

Artificial intelligence (AI) has been successful at solving numerous problems in machine perception. In radiology, AI systems are rapidly evolving and show progress in guiding treatment decisions, diagnosing, localizing disease on medical…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Usman Mahmood , Robik Shrestha , David D. B. Bates , Lorenzo Mannelli , Giuseppe Corrias , Yusuf Erdi , Christopher Kanan

Dynamic treatment regimens (DTRs), also known as treatment algorithms or adaptive interventions, play an increasingly important role in many health domains. DTRs are motivated to address the unique and changing needs of individuals by…

In this paper we present theory and algorithms enabling classes of Artificial Intelligence (AI) systems to continuously and incrementally improve with a-priori quantifiable guarantees - or more specifically remove classification errors -…

Machine Learning · Computer Science 2022-05-18 Ivan Y. Tyukin , Alexander N. Gorban , Alistair A. McEwan , Sepehr Meshkinfamfard , Lixin Tang
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