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The risk ratio is a popular tool for summarizing the relationship between a binary covariate and outcome, even when outcomes may be dependent. Investigations of infectious disease outcomes in cohort studies of individuals embedded within…

Methodology · Statistics 2017-07-20 Olga Morozova , Ted Cohen , Forrest W. Crawford

A network epidemic model is studied. The underlying social network has two different types of group structures, households and workplaces, such that each individual belongs to exactly one household and one workplace. The random network is…

Probability · Mathematics 2024-10-10 Frank Ball , Tom Britton , Peter Neal

The population-attributable fraction (PAF) is a popular epidemiological measure for the burden of a harmful exposure within a population. It is often interpreted causally as proportion of preventable cases after an elimination of exposure.…

Methodology · Statistics 2019-08-22 Maja von Cube , Martin Schumacher , Martin Wolkewitz

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

Probability · Mathematics 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

In most models of the spread of disease over contact networks it is assumed that the probabilities per unit time of disease transmission and recovery from disease are constant, implying exponential distributions of the time intervals for…

Physics and Society · Physics 2010-07-23 Brian Karrer , M. E. J. Newman

Acute respiratory diseases are transmitted over networks of social contacts. Large-scale simulation models are used to predict epidemic dynamics and evaluate the impact of various interventions, but the contact behavior in these models is…

Applications · Statistics 2012-08-27 Gail E. Potter , Mark S. Handcock , Ira M. Longini, , M. Elizabeth Halloran

A stochastic epidemic model is defined in which each individual belongs to a household, a secondary grouping (typically school or workplace) and also the community as a whole. Moreover, infectious contacts take place in these three settings…

Applications · Statistics 2009-08-17 Tom Britton , Theodore Kypraios , Philip O'Neill

Under limited available resources, strategies for mitigating the propagation of an epidemic such as random testing and contact tracing become inefficient. Here, we propose to accurately allocate the resources by computing over time an…

Physics and Society · Physics 2023-11-07 Gabriela Bayolo Soler , Miraine Dávila Felipe , Ghislaine Gayraud

We consider the spread of a Susceptible-Infected-Recovered (SIR) disease through finite populations and derive an expression for the final size distribution. Our derivation allows arbitrary distributions of the number of transmissions…

Populations and Evolution · Quantitative Biology 2019-07-12 Joel C Miller

We study a simple model of epidemics where an infected node transmits the infection to its neighbors independently with probability $p$. This is also known as the independent cascade or Susceptible-Infected-Recovered (SIR) model with fixed…

Data Structures and Algorithms · Computer Science 2021-10-19 Yeganeh Alimohammadi , Christian Borgs , Amin Saberi

Population attributable risk (PAR) is used in epidemiology to predict the impact of removing a risk factor from the population. Until recently, no standard approach for calculating confidence intervals or the variance for PAR was available…

Methodology · Statistics 2021-05-28 Sarah Pirikahu , Geoffrey Jones , Martin Hazelton

The rapid worldwide spread of the severe acute respiratory syndrome (SARS) demonstrated the potential threat an infectious disease poses in a closely interconnected and interdependent world. Here we introduce a probabilistic model which…

Disordered Systems and Neural Networks · Physics 2009-11-10 L. Hufnagel , D. Brockmann , T. Geisel

Households play an important role in disease dynamics. Many infections happening there due to the close contact, while mitigation measures mainly target the transmission between households. Therefore, one can see households as boosting the…

Populations and Evolution · Quantitative Biology 2025-01-22 Philipp Doenges , Thomas Götz , Tyll Krueger , Karol Niedzielewski , Viola Priesemann , Moritz Schaefer

First Few X (FFX) studies collect household-stratified data in the early stages of a pandemic, in order to infer severity and transmissibility of an emerging disease. We present a Bayesian method to approximately infer population-level…

Populations and Evolution · Quantitative Biology 2021-11-22 P. G. Ballard , A. J. Black , J. V. Ross

The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

This paper is concerned with the analysis of vaccination strategies in a stochastic SIR (susceptible $\to$ infected $\to$ removed) model for the spread of an epidemic amongst a population of individuals with a random network of social…

Physics and Society · Physics 2016-11-16 Frank Ball , David Sirl

Epidemic spread in single-host systems strongly depends on the population's contact network. However, little is known regarding the spread of epidemics across networks representing populations of multiple hosts. We explored cross-species…

Populations and Evolution · Quantitative Biology 2017-12-06 Shai Pilosof , Gili Greenbaum , Boris R. Krasnov , Yuval R. Zelnik

A stochastic SIR (susceptible $\to$ infective $\to$ recovered) epidemic model defined on a social network is analysed. The underlying social network is described by an Erd\H{o}s-R\'{e}nyi random graph but, during the course of the epidemic,…

Probability · Mathematics 2020-08-17 Frank Ball , Tom Britton

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

The celebrated Kermack-McKendric model of epidemics studies the transmission of a disease in a population where each individual is initially susceptible (S), may become infective (I) and then removed or recovered (R) and plays no further…

Populations and Evolution · Quantitative Biology 2015-03-13 Michael Shapiro , Edgar Delgado-Eckert