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Heralded by the initial success in speech recognition and image classification, learning-based approaches with neural networks, commonly referred to as deep learning, have spread across various fields. A primitive form of a neural network…

Robotics · Computer Science 2024-09-02 Takuma Yoneda

In this paper, we propose a new and unified approach for nonparametric regression and conditional distribution learning. Our approach simultaneously estimates a regression function and a conditional generator using a generative learning…

Machine Learning · Statistics 2023-06-28 Shanshan Song , Tong Wang , Guohao Shen , Yuanyuan Lin , Jian Huang

Despite recent advancements in single-domain or single-object image generation, it is still challenging to generate complex scenes containing diverse, multiple objects and their interactions. Scene graphs, composed of nodes as objects and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Sarthak Garg , Helisa Dhamo , Azade Farshad , Sabrina Musatian , Nassir Navab , Federico Tombari

Proteins are macromolecules that mediate a significant fraction of the cellular processes that underlie life. An important task in bioengineering is designing proteins with specific 3D structures and chemical properties which enable…

Quantitative Methods · Quantitative Biology 2022-05-31 Namrata Anand , Tudor Achim

By pretraining to synthesize coherent images from perturbed inputs, generative models inherently learn to understand object boundaries and scene compositions. How can we repurpose these generative representations for general-purpose…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Om Khangaonkar , Hamed Pirsiavash

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Recent advances in generative modeling, namely Diffusion models, have revolutionized generative modeling, enabling high-quality image generation tailored to user needs. This paper proposes a framework for the generative design of structural…

We introduce CellSegmenter, a structured deep generative model and an amortized inference framework for unsupervised representation learning and instance segmentation tasks. The proposed inference algorithm is convolutional and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Luca D'Alessio , Mehrtash Babadi

We develop a learning framework for building deformable templates, which play a fundamental role in many image analysis and computational anatomy tasks. Conventional methods for template creation and image alignment to the template have…

Computer Vision and Pattern Recognition · Computer Science 2019-10-14 Adrian V. Dalca , Marianne Rakic , John Guttag , Mert R. Sabuncu

We consider the application of deep generative models in propagating uncertainty through complex physical systems. Specifically, we put forth an implicit variational inference formulation that constrains the generative model output to…

Machine Learning · Statistics 2018-12-11 Yibo Yang , Paris Perdikaris

We introduce generative adversarial models in which the discriminator is replaced by a calibrated (non-differentiable) classifier repeatedly enhanced by domain relevant features. The role of the classifier is to prove that the actual and…

Machine Learning · Computer Science 2019-10-08 Shahar Harel , Meir Maor , Amir Ronen

Deep generative models have been wildly successful at learning coherent latent representations for continuous data such as video and audio. However, generative modeling of discrete data such as arithmetic expressions and molecular…

Machine Learning · Statistics 2017-03-07 Matt J. Kusner , Brooks Paige , José Miguel Hernández-Lobato

Robots rely on visual relocalization to estimate their pose from camera images when they lose track. One of the challenges in visual relocalization is repetitive structures in the operation environment of the robot. This calls for…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Fereidoon Zangeneh , Leonard Bruns , Amit Dekel , Alessandro Pieropan , Patric Jensfelt

Recently deep generative models have achieved impressive progress in modeling the distribution of training data. In this work, we present for the first time a generative model for 4D light field patches using variational autoencoders to…

Image and Video Processing · Electrical Eng. & Systems 2020-06-19 Paramanand Chandramouli , Kanchana Vaishnavi Gandikota , Andreas Goerlitz , Andreas Kolb , Michael Moeller

Methods allowing the synthesis of realistic cell shapes could help generate training data sets to improve cell tracking and segmentation in biomedical images. Deep generative models for cell shape synthesis require a light-weight and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 David Wiesner , Julian Suk , Sven Dummer , David Svoboda , Jelmer M. Wolterink

Generative models cover various application areas, including image, video and music synthesis, natural language processing, and molecular design, among many others. As digital generative models become larger, scalable inference in a fast…

Neural and Evolutionary Computing · Computer Science 2025-08-28 Shiqi Chen , Yuhang Li , Hanlong Chen , Aydogan Ozcan

Recent conditional image generation methods produce images of remarkable diversity, fidelity and realism. However, the majority of these methods allow conditioning only on labels or text prompts, which limits their level of control over the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Dina Bashkirova , Jose Lezama , Kihyuk Sohn , Kate Saenko , Irfan Essa

Generative artificial intelligence models learn probability distributions from data and produce novel samples that capture the salient properties of their training sets. Proteins are particularly attractive for such approaches given their…

Biomolecules · Quantitative Biology 2026-02-27 Filippo Stocco , Michele Garibbo , Noelia Ferruz

We introduce a framework for learning robust visual representations that generalize to new viewpoints, backgrounds, and scene contexts. Discriminative models often learn naturally occurring spurious correlations, which cause them to fail on…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Chengzhi Mao , Augustine Cha , Amogh Gupta , Hao Wang , Junfeng Yang , Carl Vondrick

Generating high-resolution, photo-realistic images has been a long-standing goal in machine learning. Recently, Nguyen et al. (2016) showed one interesting way to synthesize novel images by performing gradient ascent in the latent space of…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Anh Nguyen , Jeff Clune , Yoshua Bengio , Alexey Dosovitskiy , Jason Yosinski