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The design of an experiment, e.g., the setting of initial conditions, strongly influences the accuracy of the whole process of determining model parameters from data. We impose a sensitivity-based approach for choosing optimal design…

Numerical Analysis · Mathematics 2016-02-11 Stefan Kindermann , Stepan Papacek

In areas such as kernel smoothing and non-parametric regression there is emphasis on smooth interpolation and smooth statistical models. Splines are known to have optimal smoothness properties in one and higher dimensions. It is shown, with…

Computation · Statistics 2008-09-29 Ron A. Bates , Hugo Maruri-Aguilar , Henry P. Wynn

In this work, we present a fundamental mathematical model for proton transport, tailored to capture the key physical processes underpinning Proton Beam Therapy (PBT). The model provides a robust and computationally efficient framework for…

We present a new experimental-computational technology of inferring network models that predict the response of cells to perturbations and that may be useful in the design of combinatorial therapy against cancer. The experiments are…

The Bethe-Salpeter formalism represents the most accurate method available nowadays for computing neutral excitation energies and optical spectra of crystalline systems from first principles. Bethe-Salpeter calculations yield very good…

Materials Science · Physics 2016-05-04 Yannick Gillet , Matteo Giantomassi , Xavier Gonze

We calculate the spectrum of energy loss differences due to gluon radiation in high energy hard forward processes in proton-nucleus collisions as compared to proton-proton collisions. We find that the nuclear induced energy loss scales…

High Energy Physics - Phenomenology · Physics 2014-04-23 Tseh Liou , A. H. Mueller

Electron ptychography provides new opportunities to resolve atomic structures with deep sub-angstrom spatial resolution and studying electron-beam sensitive materials with high dose efficiency. In practice, obtaining accurate ptychography…

Materials Science · Physics 2022-04-26 Michael C. Cao , Zhen Chen , Yi Jiang , Yimo Han

For the effective-range function $k\cot \delta $, a pole approximation that involves a small number of parameters is derived on the basis of the Bargmann representation of the $S$ matrix. The parameters of this representation, which have a…

Nuclear Theory · Physics 2009-11-11 V. A. Babenko , N. M. Petrov

Recent developments of Perturbation Theory (PT), specifically the Effective Field Theory of Large Scale Structure (EFTofLSS) and its equivalents, have proven powerful in analyzing galaxy clustering statistics such as the galaxy power…

Cosmology and Nongalactic Astrophysics · Physics 2023-05-22 Joseph Tomlinson , Donghui Jeong

In this work, we develop and compare two innovative strategies for parameter estimation and radar detection of multiple point-like targets. The first strategy, which appears here for the first time, jointly exploits the maximum likelihood…

Signal Processing · Electrical Eng. & Systems 2020-12-02 Pia Addabbo , Jun Liu , Danilo Orlando , Giuseppe Ricci

Background: Upright proton therapy with compact delivery systems has the potential to reduce costs for treatments but could also lead to broadening of the beam penumbra due to energy selection close to the patient. Purpose: This study aims…

Medical Physics · Physics 2025-08-22 Erik Engwall , Victor Mikhalev , Johan Sundström , Otte Marthin , Viktor Wase

Proton radiotherapy promises accurate dose delivery to a tumor and minimal dose deposition to all other tissues. However, in practice the planned dose distribution may not conform to the actual one due to noisy data and different types of…

Medical Physics · Physics 2018-09-07 Jaroslav Albert , Rudi Labarbe , Edmond Sterpin

Context. The emergence of mixed modes during the subgiant phase, whose frequencies are characterized by a fast evolution with age, can potentially enable a precise determination of stellar properties, a key goal for future missions like…

Solar and Stellar Astrophysics · Physics 2025-01-20 Miguel Clara , Margarida S. Cunha , Pedro P. Avelino , Tiago L. Campante , Sébastien Deheuvels , Daniel R. Reese

This paper presents a learning-based method to solve the traditional parameterization and knot placement problems in B-spline approximation. Different from conventional heuristic methods or recent AI-based methods, the proposed method does…

Computational Engineering, Finance, and Science · Computer Science 2024-06-17 Qiang Zou , Lizhen Zhu

To deal with non-linear relations between the predictors and the response, we can use transformations to make the data look linear or approximately linear. In practice, however, transformation methods may be ineffective, and it may be more…

Methodology · Statistics 2023-01-02 Mithun Kumar Acharjee , Kumer Pial Das

A common approach to modelling extreme values is to consider the excesses above a high threshold as realisations of a non-homogeneous Poisson process. While this method offers the advantage of modelling using threshold-invariant extreme…

Applications · Statistics 2016-12-09 Paul Sharkey , Jonathan A. Tawn

Twelve physics-informed machine learning models have been trained to model binding energy residuals. Our approach begins with determining the difference between measured experimental binding energies and three different mass models. Then…

Nuclear Theory · Physics 2025-03-12 Ian Bentley , James Tedder , Marwan Gebran , Ayan Paul

Inference and optimization of real-value edge variables in sparse graphs are studied using the Bethe approximation and replica method of statistical physics. Equilibrium states of general energy functions involving a large set of real…

Disordered Systems and Neural Networks · Physics 2009-11-11 K. Y. Michael Wong , D. Saad

One of the possible ways to maintain the micrometer spatial resolution while performing ion beam analysis in the air is to increase the energy of ions. In order to explore capabilities and limitations of this approach, we have tested a…

Instrumentation and Detectors · Physics 2019-03-13 Milko Jakšić , Davit Chokheli , Stjepko Fazinić , Veljko Grilj , Natko Skukan , Ivan Sudić , Tonči Tadić , Tome Antičić

In this paper we address the problem of recovering a matrix, with inherent low rank structure, from its lower dimensional projections. This problem is frequently encountered in wide range of areas including pattern recognition, wireless…

Numerical Analysis · Computer Science 2013-12-25 Anupriya Gogna , Ankita Shukla , Angshul Majumdar