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Genetic Programming is an evolutionary algorithm that generates computer programs, or mathematical expressions, to solve complex problems. In this Guide, we demonstrate how to use Genetic Programming to develop surrogate models to mitigate…

We derive an invertible transform linking two widely used measures of species diversity: phylogenetic diversity and the expected proportions of segregating (non-constant) sites. We assume a bi-allelic, symmetric, finite site model of…

Populations and Evolution · Quantitative Biology 2011-12-06 David Bryant , Steffen Klaere

Genome rearrangements are evolutionary events that shuffle genomic architectures. Most frequent genome rearrangements are reversals, translocations, fusions, and fissions. While there are some more complex genome rearrangements such as…

Genomics · Quantitative Biology 2015-04-07 Nikita Alexeev , Rustem Aidagulov , Max A. Alekseyev

At any moment in time, evolution is faced with a formidable challenge: refining the already highly optimised design of biological species, a feat accomplished through all preceding generations. In such a scenario, the impact of random…

Populations and Evolution · Quantitative Biology 2024-02-20 Alessandro Fontana , Marios Kyriazis

The delimitation of biological species, i.e., deciding which individuals belong to the same species and whether and how many different species are represented in a data set, is key to the conservation of biodiversity. Much existing work…

Populations and Evolution · Quantitative Biology 2025-12-15 Gabriele d'Angella , Christian Hennig

Driven by the popularity of television shows such as Who Do You Think You Are? many millions of users have uploaded their family tree to web projects such as WikiTree. Analysis of this corpus enables us to investigate genealogy…

Social and Information Networks · Computer Science 2014-09-02 Michael Fire , Thomas Chesney , Yuval Elovici

Most of the problems in genetic algorithms are very complex and demand a large amount of resources that current technology can not offer. Our purpose was to develop a Java-JINI distributed library that implements Genetic Algorithms with…

Neural and Evolutionary Computing · Computer Science 2016-05-24 Marco AR Erra , Pedro MM Mitra , Agostinho C Rosa

Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. In the case of bacteria, distances can be estimated using a range of different evolutionary models, from single nucleotide…

Populations and Evolution · Quantitative Biology 2017-04-17 Stuart Serdoz , Attila Egri-Nagy , Jeremy Sumner , Barbara R. Holland , Peter D. Jarvis , Mark M. Tanaka , Andrew R. Francis

Evolution by Natural Selection is a process by which progeny inherit some properties from their progenitors with small variation. These properties are subject to Natural Selection and are called adaptive traits and carriers of the latter…

Analysis of PDEs · Mathematics 2024-01-29 Gonzalo Galiano , Yosef Cohen

Tools that effectively analyze and compare sequences are of great importance in various areas of applied computational research, especially in the framework of molecular biology. In the present paper, we introduce simple geometric criteria…

Quantitative Methods · Quantitative Biology 2013-08-14 Boris Brimkov , Valentin E. Brimkov

In this article, we review the different models and methods to understand and estimate correlated evolution within the same genome, individual or species. We describe correlated evolution among traits, among genetic components and finally…

Populations and Evolution · Quantitative Biology 2021-03-23 Guillaume Achaz , Julien Dutheil

We study the impact of a hard selective sweep on the genealogy of partially linked neutral loci in the vicinity of the positively selected allele. We consider a sexual population of stochastically varying size and, focusing on two…

Probability · Mathematics 2016-05-10 Rebekka Brink-Spalink , Charline Smadi

Evolutionary algorithms (EAs) are population-based metaheuristics, originally inspired by aspects of natural evolution. Modern varieties incorporate a broad mixture of search mechanisms, and tend to blend inspiration from nature with…

Neural and Evolutionary Computing · Computer Science 2018-05-29 David W. Corne , Michael A. Lones

The lack of diversity in a genetic algorithm's population may lead to a bad performance of the genetic operators since there is not an equilibrium between exploration and exploitation. In those cases, genetic algorithms present a fast and…

Artificial Intelligence · Computer Science 2017-02-14 Andrés Herrera-Poyatos , Francisco Herrera

Recently, much attention has been given to understanding recombination events along a chromosome in a variety of field. For instance, many population genetics problems are limited by the inaccuracy of inferred evolutionary histories of…

Quantitative Methods · Quantitative Biology 2017-10-31 Jacqueline Kane , Joseph Rusinko , Katherine Thompson

Several genetic programming systems are created, each solving a different problem. In these systems, the median number of generations G needed to evolve a working program is measured. The behavior of G is observed as the difficulty of the…

Neural and Evolutionary Computing · Computer Science 2011-02-15 Mike Stimpson

In this paper, a genetic algorithm, one of the evolutionary algorithms optimization methods, is used for the first time for the problem of finding extremal binary self-dual codes. We present a comparison of the computational times between a…

Neural and Evolutionary Computing · Computer Science 2020-12-23 Adrian Korban , Serap Sahinkaya , Deniz Ustun

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

We construct a model of speciation from evolution in an ecosystem consisting of a limited amount of energy recources. The species posses genetic information, which is inherited according to the rules of the Penna model of genetic evolution.…

Soft Condensed Matter · Physics 2007-05-23 Aleksandra Nowicka , Artur Duda , Miroslaw R. Dudek

This paper introduces the Gene Mover's Distance, a measure of similarity between a pair of cells based on their gene expression profiles obtained via single-cell RNA sequencing. The underlying idea of the proposed distance is to interpret…

Genomics · Quantitative Biology 2021-03-16 Riccardo Bellazzi , Andrea Codegoni , Stefano Gualandi , Giovanna Nicora , Eleonora Vercesi