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Correlative imaging workflows are now widely used in bioimaging and aims to image the same sample using at least two different and complementary imaging modalities. Part of the workflow relies on finding the transformation linking a source…

Quantitative Methods · Quantitative Biology 2021-08-30 Guillaume Potier , Frédéric Lavancier , Stephan Kunne , Perrine Paul-Gilloteaux

While linear registration is a critical step in MRI preprocessing pipelines, its numerical uncertainty is understudied. Using Monte-Carlo Arithmetic (MCA) simulations, we assessed the most commonly used linear registration tools within…

Quantitative Methods · Quantitative Biology 2025-09-01 Niusha Mirhakimi , Yohan Chatelain , Tristan Glatard , Jean-Baptiste Poline

We evaluate two different methods for the integration of prediction uncertainty into diagnostic image classifiers to increase patient safety in deep learning. In the first method, Monte Carlo sampling is applied with dropout at test time to…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Reliable uncertainty quantification is crucial for trustworthy decision-making and the deployment of AI models in medical imaging. While prior work has explored the ability of neural networks to quantify predictive, epistemic, and aleatoric…

Machine Learning · Statistics 2025-08-07 Simon Baur , Wojciech Samek , Jackie Ma

Diffusion models, while trained for image generation, have emerged as powerful foundational feature extractors for downstream tasks. We find that off-the-shelf diffusion models, trained exclusively to generate natural RGB images, can…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Nurislam Tursynbek , Hastings Greer , Basar Demir , Marc Niethammer

Purpose: Optical imaging is evolving as a key technique for advanced sensing in the operating room. Recent research has shown that machine learning algorithms can be used to address the inverse problem of converting pixel-wise multispectral…

Spatial registration across different visual modalities is a critical but formidable step in multi-modality image fusion for real-world perception. Although several methods are proposed to address this issue, the existing registration-based…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Congcong Bian , Haolong Ma , Hui Li , Zhongwei Shen , Xiaoqing Luo , Xiaoning Song , Xiao-Jun Wu

In this work, we conducted a survey on different registration algorithms and investigated their suitability for hyperspectral historical image registration applications. After the evaluation of different algorithms, we choose an intensity…

Computer Vision and Pattern Recognition · Computer Science 2017-12-14 AmirAbbas Davari , Tobias Lindenberger , Armin Häberle , Vincent Christlein , Andreas Maier , Christian Riess

Accurate uncertainty estimation is a critical need for the medical imaging community. A variety of methods have been proposed, all direct extensions of classification uncertainty estimations techniques. The independent pixel-wise…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Thierry Judge , Olivier Bernard , Mihaela Porumb , Agis Chartsias , Arian Beqiri , Pierre-Marc Jodoin

Due to complexity and invisibility of human organs, diagnosticians need to analyze medical images to determine where the lesion region is, and which kind of disease is, in order to make precise diagnoses. For satisfying clinical purposes…

Quantitative Methods · Quantitative Biology 2017-05-18 Roberto Cavoretto , Alessandra De Rossi , Roberta Freda , Hanli Qiao , Ezio Venturino

The problem of learning a correspondence relationship between nodes of two networks has drawn much attention of the computer science community and recently that of statisticians. The unseeded version of this problem, in which we do not know…

Methodology · Statistics 2018-08-24 Yuan Zhang

Deformable image registration estimates voxel-wise correspondences between images through spatial transformations, and plays a key role in medical imaging. While deep learning methods have significantly reduced runtime, efficiently handling…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Tianran Li , Marius Staring , Yuchuan Qiao

Cervical cancer is one of the leading causes of death in women, and brachytherapy is currently the primary treatment method. However, it is important to precisely define the extent of paracervical tissue invasion to improve cancer diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2024-05-22 Jjahao Zhang , Yin Gu , Deyu Sun , Yuhua Gao , Ming Gao , Ming Cui , Teng Zhang , He Ma

In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Zekang Chen , Jia Wei , Rui Li

This paper proposes a global approach for the multi-view registration of unordered range scans. As the basis of multi-view registration, pair-wise registration is very pivotal. Therefore, we first select a good descriptor and accelerate its…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Jihua Zhu , Siyu Xu , Zutao Jiang , Shanmin Pang , Jun Wang , Zhongyu Li

In electrocardiography, the "classic" inverse problem is the reconstruction of electric potentials at a surface enclosing the heart from remote recordings at the body surface and an accurate description of the anatomy. The latter being…

Numerical Analysis · Mathematics 2021-06-29 Lia Gander , Rolf Krause , Michael Multerer , Simone Pezzuto

Deep metrics have been shown effective as similarity measures in multi-modal image registration; however, the metrics are currently constructed from aligned image pairs in the training data. In this paper, we propose a strategy for learning…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 Alireza Sedghi , Jie Luo , Alireza Mehrtash , Steve Pieper , Clare M. Tempany , Tina Kapur , Parvin Mousavi , William M. Wells

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

We address the selection and evaluation of uncertain segmentation methods in medical imaging and present two case studies: prostate segmentation, illustrating that for minimal annotator variation simple deterministic models can suffice, and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Kilian Zepf , Jes Frellsen , Aasa Feragen

In engineering applications almost all processes are described with the help of models. Especially forming machines heavily rely on mathematical models for control and condition monitoring. Inaccuracies during the modeling, manufacturing…