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This study employed the MIMIC-IV database as data source to investigate the use of dynamic, high-frequency, multivariate time-series vital signs data, including temperature, heart rate, mean blood pressure, respiratory rate, and SpO2,…

Machine Learning · Computer Science 2023-07-13 Tongyue Shi , Zhilong Zhang , Wentie Liu , Junhua Fang , Jianguo Hao , Shuai Jin , Huiying Zhao , Guilan Kong

Early prediction of patients at risk of clinical deterioration can help physicians intervene and alter their clinical course towards better outcomes. In addition to the accuracy requirement, early warning systems must make the predictions…

Machine Learning · Computer Science 2021-02-16 Ibrahim Hammoud , Prateek Prasanna , IV Ramakrishnan , Adam Singer , Mark Henry , Henry Thode

Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…

Vital signs and laboratory values are routinely used to guide clinical decision-making for polytrauma patients, such as the decision to use damage control techniques versus early definitive fracture fixation. Prior multivariate models have…

Quantitative Methods · Quantitative Biology 2020-10-09 Adam J. Starr , Manjula Julka , Arun Nethi , John D. Watkins , Ryan W. Fairchild , Michael W. Cripps , Dustin Rinehart , Hayden N. Box

Vital signs are crucial in intensive care units (ICUs). They are used to track the patient's state and to identify clinically significant changes. Predicting vital sign trajectories is valuable for early detection of adverse events.…

Machine Learning · Computer Science 2024-03-28 Bar Eini Porat , Danny Eytan , Uri Shalit

Human mortality patterns and trajectories in closely related populations are likely linked together and share similarities. It is always desirable to model them simultaneously while taking their heterogeneity into account. This paper…

Methodology · Statistics 2024-12-30 Ka Kin Lam , Bo Wang

For severely affected COVID-19 patients, it is crucial to identify high-risk patients and predict survival and need for intensive care (ICU). Most of the proposed models are not well reported making them less reproducible and prone to high…

Machine Learning · Computer Science 2024-03-29 Mahbubunnabi Tamala , Mohammad Marufur Rahmanb , Maryam Alhasimc , Mobarak Al Mulhimd , Mohamed Derichee

Sepsis remains one of the leading causes of mortality in intensive care units, where timely and accurate treatment decisions can significantly impact patient outcomes. In this work, we propose an interpretable decision support framework.…

Machine Learning · Computer Science 2026-01-21 Punit Kumar , Vaibhav Saran , Divyesh Patel , Nitin Kulkarni , Alina Vereshchaka

ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics…

Machine Learning · Computer Science 2019-10-08 Zhiheng Li , Xinyue Xing , Bingzhang Lu , Zhixiang Li

Background: Accurate short-term readmission prediction of ICU patients is significant in improving the efficiency of resource assignment by assisting physicians in making discharge decisions. Clinically, both individual static static and…

Machine Learning · Computer Science 2024-07-17 Zhe Sun , Runzhi Li , Jing Wang , Gang Chen , Siyu Yan , Lihong Ma

Probabilistic model-based diagnosis computes the posterior probabilities of failure of components from the prior probabilities of component failure and observations of system behavior. One problem with this method is that such priors are…

Artificial Intelligence · Computer Science 2013-02-21 Sampath Srinivas

The association between preoperative cognitive status and surgical outcomes is a critical, yet scarcely explored area of research. Linking intraoperative data with postoperative outcomes is a promising and low-cost way of evaluating…

Many in-hospital mortality risk prediction scores dichotomize predictive variables to simplify the score calculation. However, hard thresholding in these additive stepwise scores of the form "add x points if variable v is above/below…

Machine Learning · Statistics 2015-04-30 Natalia M. Arzeno , Karla A. Lawson , Sarah V. Duzinski , Haris Vikalo

Fitting probabilistic models to data is often difficult, due to the general intractability of the partition function. We propose a new parameter fitting method, Minimum Probability Flow (MPF), which is applicable to any parametric model. We…

Machine Learning · Computer Science 2020-07-21 Jascha Sohl-Dickstein , Peter Battaglino , Michael R. DeWeese

The intensive care units (ICUs) are responsible for generating a wealth of useful data in the form of Electronic Health Record (EHR). This data allows for the development of a prediction tool with perfect knowledge backing. We aimed to…

Machine Learning · Computer Science 2020-07-28 Saumil Maheshwari , Rohit Verma , Anupam Shukla , Ritu Tiwari , Rishu Garg

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

Machine Learning · Computer Science 2025-01-03 Arseniy Shumilov , Yueting Zhu , Negin Ashrafi , Armin Abdollahi , Greg Placencia , Kamiar Alaei , Maryam Pishgar

The significance of mortality modeling extends across multiple research areas, ranging from life insurance valuation to optimal lifetime decision-making. Existing approaches, such as mortality laws and factor-based models, often fall short…

Applications · Statistics 2024-10-23 Xiaobai Zhu , Kenneth Q. Zhou , Zijia Wang

Accurately predicting hospital length-of-stay at the time a patient is admitted to hospital may help guide clinical decision making and resource allocation. In this study we aim to build a decision support system that predicts hospital…

Artificial Intelligence · Computer Science 2023-08-08 Mucahit Cevik , Can Kavaklioglu , Fahad Razak , Amol Verma , Ayse Basar

We present ICU-Sepsis, an environment that can be used in benchmarks for evaluating reinforcement learning (RL) algorithms. Sepsis management is a complex task that has been an important topic in applied RL research in recent years.…

Machine Learning · Computer Science 2025-03-12 Kartik Choudhary , Dhawal Gupta , Philip S. Thomas

Unlike in a clinical trial, where researchers get to determine the least number of positive and negative samples required, or in a machine learning study where the size and the class distribution of the validation set is static and known,…

Machine Learning · Computer Science 2024-02-13 Jiacheng Liu , Lisa Kirkland , Jaideep Srivastava
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