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Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

Machine Learning · Computer Science 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

We present a machine learning pipeline and model that uses the entire uncurated EHR for prediction of in-hospital mortality at arbitrary time intervals, using all available chart, lab and output events, without the need for pre-processing…

Machine Learning · Computer Science 2019-09-18 Jacob Deasy , Pietro Liò , Ari Ercole

Heart failure affects millions of people worldwide, significantly reducing quality of life and leading to high mortality rates. Despite extensive research, the relationship between heart failure and mortality rates among ICU patients is not…

Machine Learning · Computer Science 2024-09-04 Negin Ashrafi , Armin Abdollahi , Jiahong Zhang , Maryam Pishgar

Clinical practice in intensive care units (ICUs) requires early warnings when a patient's condition is about to deteriorate so that preventive measures can be undertaken. To this end, prediction algorithms have been developed that estimate…

Machine Learning · Computer Science 2021-02-18 Yilmazcan Özyurt , Mathias Kraus , Tobias Hatt , Stefan Feuerriegel

Prediction of mortality in intensive care unit (ICU) patients typically relies on black box models (that are unacceptable for use in hospitals) or hand-tuned interpretable models (that might lead to the loss in performance). We aim to…

Machine Learning · Computer Science 2025-01-09 Chloe Qinyu Zhu , Muhang Tian , Lesia Semenova , Jiachang Liu , Jack Xu , Joseph Scarpa , Cynthia Rudin

Background: Patients with both diabetes mellitus (DM) and atrial fibrillation (AF) face elevated mortality in intensive care units (ICUs), yet models targeting this high-risk group remain limited. Objective: To develop an interpretable…

Machine Learning · Computer Science 2025-06-23 Li Sun , Shuheng Chen , Yong Si , Junyi Fan , Maryam Pishgar , Elham Pishgar , Kamiar Alaei , Greg Placencia

Patient time series classification faces challenges in high degrees of dimensionality and missingness. In light of patient similarity theory, this study explores effective temporal feature engineering and reduction, missing value…

Artificial Intelligence · Computer Science 2017-05-02 Mohammad Amin Morid , Olivia R. Liu Sheng , Samir Abdelrahman

Mortality risk is a major concern to patients have just been discharged from the intensive care unit (ICU). Many studies have been directed to construct machine learning models to predict such risk. Although these models are highly…

Applications · Statistics 2021-01-20 Eugene T. Y. Ang , Milashini Nambiar , Yong Sheng Soh , Vincent Y. F. Tan

The development of respiratory failure is common among patients in intensive care units (ICU). Large data quantities from ICU patient monitoring systems make timely and comprehensive analysis by clinicians difficult but are ideal for…

Machine Learning · Computer Science 2021-05-13 Matthias Hüser , Martin Faltys , Xinrui Lyu , Chris Barber , Stephanie L. Hyland , Tobias M. Merz , Gunnar Rätsch

Accurate Intensive Care Unit (ICU) outcome prediction is critical for improving patient treatment quality and ICU resource allocation. Existing research mainly focuses on structured data, e.g. demographics and vital signs, and lacks…

Information Theory · Computer Science 2025-02-26 Yucheng Ruan , Daniel J. Tan , See Kiong Ng , Ling Huang , Mengling Feng

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be…

Machine Learning · Computer Science 2018-12-13 Laura A. Barrett , Seyedeh Neelufar Payrovnaziri , Jiang Bian , Zhe He

Intensive care unit (ICU) data are highly irregular, heterogeneous, and temporally fragmented, posing challenges for generalizable clinical prediction. We present PULSE-ICU, a self-supervised foundation model that learns event-level ICU…

Machine Learning · Computer Science 2025-12-01 Sejeong Jang , Joo Heung Yoon , Hyo Kyung Lee

Patients resuscitated from cardiac arrest (CA) face a high risk of neurological disability and death, however pragmatic methods are lacking for accurate and reliable prognostication. The aim of this study was to build computational models…

Accurate early prediction of in-hospital mortality in intensive care units (ICUs) is essential for timely clinical intervention and efficient resource allocation. This study develops and evaluates machine learning models that integrate both…

Machine Learning · Computer Science 2025-10-22 Nursultan Mamatov , Philipp Kellmeyer

The pressure of ever-increasing patient demand and budget restrictions make hospital bed management a daily challenge for clinical staff. Most critical is the efficient allocation of resource-heavy Intensive Care Unit (ICU) beds to the…

Machine Learning · Computer Science 2021-02-25 Emma Rocheteau , Pietro Liò , Stephanie Hyland

Postoperative stroke remains a critical complication in elderly surgical intensive care unit (SICU) patients, contributing to prolonged hospitalization, elevated healthcare costs, and increased mortality. Accurate early risk stratification…

Quantitative Methods · Quantitative Biology 2025-06-05 Tinghuan Li , Shuheng Chen , Junyi Fan , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

As more Intensive Care Unit (ICU) data becomes available, the interest in developing clinical prediction models to improve healthcare protocols increases. However, the lack of data quality still hinders clinical prediction using Machine…

The intensive care unit (ICU) comprises a complex hospital environment, where decisions made by clinicians have a high level of risk for the patients' lives. A comprehensive care pathway must then be followed to reduce p complications.…

Patient status, angiographic and procedural characteristics encode crucial signals for predicting long-term outcomes after percutaneous coronary intervention (PCI). The aim of the study was to develop a predictive model for assessing the…

Machine Learning · Computer Science 2025-12-30 Daniil Burakov , Ivan Petrov , Dmitrii Khelimskii , Ivan Bessonov , Mikhail Lazarev