Related papers: Asymptotic behavior of Eigen's quasispecies model
We analyse a continuum model for genetic circuits based on a partial integro-differential equation initially proposed in Friedman, Cai \& Xie (2006) as an approximation of a chemical master equation. We use entropy methods to show…
Eigen's quasi-species model describes viruses as ensembles of different mutants of a high fitness "master" genotype. Mutants are assumed to have lower fitness than the master type, yet they coexist with it forming the quasi-species. When…
This paper investigates the asymptotic behavior of the extremes of a sequence of generalized Oppenheim random variables. Particularly, we establish conditions under which some normalized extremes of sequences arising from Oppenheim…
We study the asymptotic behavior of the trajectory of a nonautonomous evolution equation governed by a quasi-nonexpansive operator in Hilbert spaces. We prove the weak convergence of the trajectory to a fixed point of the operator by…
When mutations are rampant, quasispecies theory or Eigen's model predicts that the fittest type in a population may not dominate. Beyond a critical mutation rate, the population may even be delocalized completely from the peak of the…
For the general class of quasifree fermionic right mover/left mover systems over the infinitely extended two-sided discrete line introduced in [8] within the algebraic framework of quantum statistical mechanics, we study the von Neumann…
We suggest a natural approach that leads to a modification of classical quasispecies models and incorporates the possibility of population extinction in addition to growth. The resulting modified models are called open. Their essential…
The purpose of this article is to present a general method to find limiting laws for some renormalized statistics on random permutations. The model considered here is Ewens sampling model, which generalizes uniform random permutations. We…
We derive the asymptotic expansion at infinity for embedded ends of uniformly elliptic Weingarten surfaces with finite total curvature in $\mathbb{R}^3$, and we establish a maximum principle at infinity. Furthermore, we solve the Dirichlet…
We consider Ewens random permutations of length $n$ conditioned to have no cycle longer than $n^\beta$ with $0<\beta<1$ and to study the asymptotic behaviour as $n\to\infty$. We obtain very precise information on the joint distribution of…
The long-time asymptotic behavior is studied for a long-range variant of the Emch-Radin model of interacting spins. We derive upper and lower bounds on the expectation values of a class of observables. We prove analytically that the time…
We analyze the asymptotic behavior for a system of fully nonlinear parabolic and elliptic quasi variational inequalities. These equations are related to robust switching control problems introduced in [3]. We prove that, as time horizon…
Consider the following Lane-Emden system with Dirichlet boundary conditions: \[ -\Delta U = |V|^{\beta-1}V,\ -\Delta V = |U|^{\alpha-1}U \text{ in }\Omega,\qquad U=V= 0 \text{ on }\partial \Omega, \] in a bounded domain $\Omega$, for…
A quasispecies is a set of interrelated genotypes that have reached a situation of equilibrium while evolving according to the usual Darwinian principles of selection and mutation. Quasispecies studies invariably assume that it is possible…
We explore some aspects of the relationship between biological evolution processes and the mathematical theory of records. For Eigen's quasispecies model with an uncorrelated fitness landscape, we show that the evolutionary trajectories…
We consider the Moran model on the sharp peak landscape, in the asymptotic regime studied in [3], where a quasispecies is formed. We find explicitly the distribution of this quasispecies.
Systems of a large number N of globally coupled maps have become popular as a relatively simple prototype of high-dimensional dynamics, showing many interesting and typical phenomena like synchronisation, cluster formation and…
Static spherically symmetric solutions to the Einstein-Euler equations with prescribed central densities are known to exist, be unique and smooth for reasonable equations of state. Some criteria are also available to decide whether…
Viruses present an amazing genetic variability. An ensemble of infecting viruses, also called a viral quasispecies, is a cloud of mutants centered around a specific genotype. The simplest model of evolution, whose equilibrium state is…
We provide an asymptotic analysis of a nonlinear integro-differential equation describing the evolutionary dynamics of a population which reproduces sexually and which is subject to selection and competition. The sexual reproduction is…