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Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…
High angular resolution diffusion imaging (HARDI) is a type of diffusion magnetic resonance imaging (dMRI) that measures diffusion signals on a sphere in q-space. It has been widely used in data acquisition for human brain structural…
Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…
Diffusion tensor imaging (DTI) is a widely used method for studying brain white matter development and degeneration. However, standard DTI estimation methods depend on a large number of high-quality measurements. This would require long…
Post-traumatic epilepsy (PTE) is a life-long complication of traumatic brain injury (TBI) and is a major public health problem that has an estimated incidence that ranges from 2%-50%, depending on the severity of the TBI. Currently, the…
Neighborhood selection is a widely used method used for estimating the support set of sparse precision matrices, which helps determine the conditional dependence structure in undirected graphical models. However, reporting only point…
In this paper, we focus on how to locate the relevant or discriminative brain regions related with external stimulus or certain mental decease, which is also called support identification, based on the neuroimaging data. The main difficulty…
Brain network analysis for traumatic brain injury (TBI) patients is critical for its consciousness level assessment and prognosis evaluation, which requires the segmentation of certain consciousness-related brain regions. However, it is…
Diffusion tensor imaging (DTI) is a novel modality of magnetic resonance imaging that allows noninvasive mapping of the brain's white matter. A particular map derived from DTI measurements is a map of water principal diffusion directions,…
This paper presents a new approach for relatively accurate brain region of interest (ROI) detection from dynamic susceptibility contrast (DSC) perfusion magnetic resonance (MR) images of a human head with abnormal brain anatomy. Such images…
Diffusion tensor imaging (DTI) plays a key role in analyzing the physical structures of biological tissues, particularly in reconstructing fiber tracts of the human brain in vivo. On the one hand, eigenvalues of diffusion tensors (DTs)…
Motivated by the problem of inferring the graph structure of functional connectivity networks from multi-level functional magnetic resonance imaging data, we develop a valid inference framework for high-dimensional graphical models that…
Prognoses of Traumatic Brain Injury (TBI) outcomes are neither easily nor accurately determined from clinical indicators. This is due in part to the heterogeneity of damage inflicted to the brain, ultimately resulting in diverse and complex…
Diffusion Tensor Imaging (DTI) allows estimating the position, orientation and dimension of bundles of nerve pathways. This non-invasive imaging technique takes advantage of the diffusion of water molecules and determines the diffusion…
We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…
Automated segmentation of medical imaging is of broad interest to clinicians and machine learning researchers alike. The goal of segmentation is to increase efficiency and simplicity of visualization and quantification of regions of…
A central question in multimodal neuroimaging analysis is to understand the association between two imaging modalities and to identify brain regions where such an association is statistically significant. In this article, we propose a…
The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…
Traumatic brain injury (TBI) is caused by a sudden trauma to the head that may result in hematomas and contusions and can lead to stroke or chronic disability. An accurate quantification of the lesion volumes and their locations is…
Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…