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The underlying physiological mechanisms of generating conscious states are still unknown. To make progress on the problem of consciousness, we will need to experimentally design a system that evolves in a similar way our brains do. Recent…

Emerging Technologies · Computer Science 2014-11-20 Dorian Aur

Informatics studies all aspects of the structure of natural and artificial information systems. Theoretical and abstract approaches to information have made great advances, but human information processing is still unmatched in many areas,…

Artificial Intelligence · Computer Science 2021-01-12 Włodzisław Duch

Living systems are often described utilizing informational analogies. An important open question is whether information is merely a useful conceptual metaphor, or intrinsic to the operation of biological systems. To address this question,…

Molecular Networks · Quantitative Biology 2015-08-19 Hyunju Kim , Paul Davies , Sara Imari Walker

Computational complexity is a core theory of computer science, which dictates the degree of difficulty of computation. There are many problems with high complexity that we have to deal, which is especially true for AI. This raises a big…

Computational Complexity · Computer Science 2023-01-10 Chuyu Xiong

This document is written with the intention to describe in detail a method and means by which a computer program can reason about the world and in so doing, increase its analogue to a living system. As the literature is rife and it is…

Artificial Intelligence · Computer Science 2017-05-23 Christopher A. Tucker

Many biological functions are executed by molecular machines, which consume energy and convert it into mechanical work. Biological machines have evolved to transport cargo, facilitate folding of proteins and RNA, remodel chromatin and…

Biological Physics · Physics 2020-04-15 Mauro L. Mugnai , Changbong Hyeon , Michael Hinczewski , D. Thirumalai

Biologically-inspired methods such as evolutionary algorithms and neural networks are proving useful in the field of information fusion. Artificial Immune Systems (AISs) are a biologically-inspired approach which take inspiration from the…

Artificial Intelligence · Computer Science 2010-07-05 Jamie Twycross , Uwe Aickelin

For decades, researchers have been applying computer simulation to address problems in biology. However, many of these "grand challenges" in computational biology, such as simulating how proteins fold, remained unsolved due to their great…

Biological Physics · Physics 2009-01-08 Stefan M. Larson , Christopher D. Snow , Michael Shirts , Vijay S. Pande

Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a…

Populations and Evolution · Quantitative Biology 2012-07-25 Christoph Adami

Biological signaling is imagined as a combination of activation and transport. The former is triggered by local molecular interactions and the latter is the result of molecular diffusion. However, other fundamental physical principles of…

Biological Physics · Physics 2016-12-07 Bernhard Fichtl , Matthias F. Schneider

A complex system is a system composed of many interacting parts, often called agents, which displays collective behavior that does not follow trivially from the behaviors of the individual parts. Examples include condensed matter systems,…

Statistical Mechanics · Physics 2011-12-08 M. E. J. Newman

The vision of Organic Computing addresses challenges that arise in the design of future information systems that are comprised of numerous, heterogeneous, resource-constrained and error-prone components or devices. Here, the notion organic…

Networking and Internet Architecture · Computer Science 2012-04-26 Ingo Scholtes , Claudio Juan Tessone

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

Many real-world dynamic systems, both natural and artificial, are understood to be performing computations. For artificial dynamic systems, explicitly designed to perform computation - such as digital computers - by construction, we can…

Computational Physics · Physics 2026-02-24 David H. Wolpert , Jan Korbel

Interactions with large language models have led to the suggestion that these models may soon be conscious. From the perspective of neuroscience, this position is difficult to defend. For one, the inputs to large language models lack the…

Neurons and Cognition · Quantitative Biology 2023-08-29 Jaan Aru , Matthew Larkum , James M. Shine

Digital life, a form of life generated by computer programs or artificial intelligence systems, it possesses self-awareness, thinking abilities, emotions, and subjective consciousness. Achieving it involves complex neural networks,…

Human-Computer Interaction · Computer Science 2023-10-24 Qikang Zhang

Complex systems, from the human brain to the global economy, are made of multiple elements that interact in such ways that the behaviour of the `whole' often seems to be more than what is readily explainable in terms of the `sum of the…

Neurons and Cognition · Quantitative Biology 2021-09-28 Pedro A. M. Mediano , Fernando E. Rosas , Andrea I Luppi , Robin L. Carhart-Harris , Daniel Bor , Anil K. Seth , Adam B. Barrett

Creating autonomous, self-supporting, self-replicating, sustainable systems is a great challenge. To some extent, understanding life means not only being able to create it from scratch, but also improving, supporting, saving it, or even…

Robotics · Computer Science 2011-11-07 Serge Kernbach

The Web has made it possible to harness human cognition en masse to achieve new capabilities. Some of these successes are well known; for example Wikipedia has become the go-to place for basic information on all things; Duolingo engages…

Human-Computer Interaction · Computer Science 2015-05-27 Pietro Michelucci , Lea Shanley , Janis Dickinson , Haym Hirsh

Artificial computing machinery transforms representations through an objective process, to be interpreted subjectively by humans, so the machine and the interpreter are different entities, but in the putative natural computing both…

Artificial Intelligence · Computer Science 2025-06-17 Luis A. Pineda