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With the astonishing rate that the genomic and metagenomic sequence data sets are accumulating, there are many reasons to constrain the data analyses. One approach to such constrained analyses is to focus on select subsets of gene families…

Genomics · Quantitative Biology 2014-03-05 Dongying Wu , Guillaume Jospin , Jonathan A. Eisen

Identification of tree species plays a key role in forestry related tasks like forest conservation, disease diagnosis and plant production. There had been a debate regarding the part of the tree to be used for differentiation, whether it…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Sahil Faizal

Semi-labeled trees are phylogenies whose internal nodes may be labeled by higher-order taxa. Thus, a leaf labeled Mus musculus could nest within a subtree whose root node is labeled Rodentia, which itself could nest within a subtree whose…

Data Structures and Algorithms · Computer Science 2016-05-09 Yun Deng , David Fernández-Baca

Phylogenomics is a new field which applies to tools in phylogenetics to genome data. Due to a new technology and increasing amount of data, we face new challenges to analyze them over a space of phylogenetic trees. Because a space of…

Combinatorics · Mathematics 2020-05-15 Ruriko Yoshida

Marine ecosystems are vital for the planet's health, but human activities such as climate change, pollution, and overfishing pose a constant threat to marine species. Accurate classification and monitoring of these species can aid in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Kohav Dey , Krishna Bajaj , K S Ramalakshmi , Samuel Thomas , Sriram Radhakrishna

In an effort to catalog insect biodiversity, we propose a new large dataset of hand-labelled insect images, the BIOSCAN-Insect Dataset. Each record is taxonomically classified by an expert, and also has associated genetic information…

Bayesian phylogenetic inference is currently done via Markov chain Monte Carlo (MCMC) with simple proposal mechanisms. This hinders exploration efficiency and often requires long runs to deliver accurate posterior estimates. In this paper,…

Machine Learning · Statistics 2024-05-24 Cheng Zhang , Frederick A. Matsen

The ability to quickly and accurately identify microbial species in a sample, known as metagenomic profiling, is critical across various fields, from healthcare to environmental science. This paper introduces a novel method to profile…

Genomics · Quantitative Biology 2025-04-10 Riselda Kodra , Hadjer Benmeziane , Irem Boybat , William Andrew Simon

Fixed tree topologies are widely used in phylodynamic analyses to reduce computational burden, yet the consequences of this assumption remain insufficiently understood. Here, we systematically assess the impact of various fixed-topology…

Populations and Evolution · Quantitative Biology 2025-12-01 Mathieu Fourment , Jiansi Gao , Marc A Suchard , Frederick A Matsen

Understanding how biological communities respond to environmental changes is a key challenge in ecology and ecosystem management. The apparent decline of insect populations necessitates more biomonitoring but the time-consuming sorting and…

Massively parallel sequencing techniques have revolutionized biological and medical sciences by providing unprecedented insight into the genomes of humans, animals, and microbes. Modern sequencing platforms generate enormous amounts of…

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

We propose a method for the classification of objects that are structured as random trees. Our aim is to model a distribution over the node label assignments in settings where the tree data structure is associated with node attributes…

Machine Learning · Computer Science 2024-09-18 Wouter W. L. Nuijten , Vlado Menkovski

DNA-based biodiversity surveys involve collecting physical samples from survey sites and assaying the contents in the laboratory to detect species via their diagnostic DNA sequences. DNA-based surveys are increasingly being adopted for…

DNA barcoding has emerged as a cost-effective approach for species identification. However, the scarcity of tools used for searching the booming reference database becomes an obstacle, currently with BLAST as the only practical choice.…

Populations and Evolution · Quantitative Biology 2014-07-15 Long Fan , Ka Hou Chu

Molecular and morphological characters, as important parts of biological taxonomy, are contradictory but need to be integrated. Organism's image recognition and bioinformatics are emerging and hot problems nowadays but with a gap between…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Jiewen Xiao , Wenbin Liao , Ming Zhang , Jing Wang , Jianxin Wang , Yihua Yang

The PHASE software package allows phylogenetic tree construction with a number of evolutionary models designed specifically for use with RNA sequences that have conserved secondary structure. Evolution in the paired regions of RNAs occurs…

Populations and Evolution · Quantitative Biology 2007-05-23 Cendrine Hudelot , Vivek Gowri-Shankar , Howsun Jow , Magnus Rattray , Paul G. Higgs

Cryopreservation is beset with the challenge of protocol alignment across a wide range of cell types and process variables. By taking a cross-sectional assessment of previously published cryopreservation data (sample means and standard…

Quantitative Methods · Quantitative Biology 2014-04-08 S Sambu

Traditionally, phylogeny and sequence alignment are estimated separately: first estimate a multiple sequence alignment and then infer a phylogeny based on the sequence alignment estimated in the previous step. However, uncertainty in the…

Applications · Statistics 2014-11-25 Heejung Shim , Bret Larget

For a phylogenetic tree, the phylogenetic diversity of a set A of taxa is the total weight of edges on paths to A. Finding small sets of maximal diversity is crucial for conservation planning, as it indicates where limited resources can be…

Data Structures and Algorithms · Computer Science 2025-10-29 Mark Jones , Jannik Schestag