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Unravelling protein distributions within individual cells is key to understanding their function and state and indispensable to developing new treatments. Here we present the Hybrid subCellular Protein Localiser (HCPL), which learns from…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Syed Sameed Husain , Eng-Jon Ong , Dmitry Minskiy , Mikel Bober-Irizar , Amaia Irizar , Miroslaw Bober

Gene mutation prediction in hepatocellular carcinoma (HCC) is of great diagnostic and prognostic value for personalized treatments and precision medicine. In this paper, we tackle this problem with multi-instance multi-label learning to…

Machine Learning · Computer Science 2022-03-24 Kaixin Xu , Ziyuan Zhao , Jiapan Gu , Zeng Zeng , Chan Wan Ying , Lim Kheng Choon , Thng Choon Hua , Pierce KH Chow

Knowing the location of a protein within the cell is important for understanding its function, role in biological processes, and potential use as a drug target. Much progress has been made in developing computational methods that predict…

Quantitative Methods · Quantitative Biology 2013-08-02 Ramanuja Simha , Hagit Shatkay

Understanding and extracting the patterns of microscopy images has been a major challenge in the biomedical field. Although trained scientists can locate the proteins of interest within a human cell, this procedure is not efficient and…

Computer Vision and Pattern Recognition · Computer Science 2020-06-09 Hanke Chen

Multi-label classification is a common challenge in various machine learning applications, where a single data instance can be associated with multiple classes simultaneously. The current paper proposes a novel tree-based method for…

Methodology · Statistics 2024-05-01 Chhavi Tyagi , Wenge Guo

This paper addresses a multi-label predictive fault classification problem for multidimensional time-series data. While fault (event) detection problems have been thoroughly studied in literature, most of the state-of-the-art techniques…

Machine Learning · Computer Science 2020-01-29 Wenyu Zhang , Devesh K. Jha , Emil Laftchiev , Daniel Nikovski

In this paper a high speed neural network classifier based on extreme learning machines for multi-label classification problem is proposed and dis-cussed. Multi-label classification is a superset of traditional binary and multi-class…

Machine Learning · Computer Science 2016-09-06 Meng Joo Er , Rajasekar Venkatesan , Ning Wang

Unlike the typical classification setting where each instance is associated with a single class, in multi-label learning each instance is associated with multiple classes simultaneously. Therefore the learning task in this setting is to…

Machine Learning · Computer Science 2022-11-30 Harris Papadopoulos

In real-world applications, as data availability increases, obtaining labeled data for machine learning (ML) projects remains challenging due to the high costs and intensive efforts required for data annotation. Many ML projects,…

Machine Learning · Computer Science 2024-12-24 Ismail Hakki Karaman , Gulser Koksal , Levent Eriskin , Salih Salihoglu

Class-imbalance is an inherent characteristic of multi-label data which affects the prediction accuracy of most multi-label learning methods. One efficient strategy to deal with this problem is to employ resampling techniques before…

Machine Learning · Computer Science 2021-05-18 Bin Liu , Grigorios Tsoumakas

Motivated by applications in protein function prediction, we consider a challenging supervised classification setting in which positive labels are scarce and there are no explicit negative labels. The learning algorithm must thus select…

Machine Learning · Computer Science 2019-01-28 Marco Frasca , Nicolò Cesa-Bianchi

Real-world large-scale datasets are heteroskedastic and imbalanced -- labels have varying levels of uncertainty and label distributions are long-tailed. Heteroskedasticity and imbalance challenge deep learning algorithms due to the…

Machine Learning · Computer Science 2021-03-19 Kaidi Cao , Yining Chen , Junwei Lu , Nikos Arechiga , Adrien Gaidon , Tengyu Ma

Class imbalance is an inherent characteristic of multi-label data that hinders most multi-label learning methods. One efficient and flexible strategy to deal with this problem is to employ sampling techniques before training a multi-label…

Machine Learning · Computer Science 2020-05-20 Bin Liu , Konstantinos Blekas , Grigorios Tsoumakas

Neural networks trained on real-world datasets with long-tailed label distributions are biased towards frequent classes and perform poorly on infrequent classes. The imbalance in the ratio of positive and negative samples for each class…

Computer Vision and Pattern Recognition · Computer Science 2021-05-25 Kevin Duarte , Yogesh S. Rawat , Mubarak Shah

Over the last few years, convolutional neural networks (CNNs) have dominated the field of computer vision thanks to their ability to extract features and their outstanding performance in classification problems, for example in the automatic…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Helena Liz , Javier Huertas-Tato , Manuel Sánchez-Montañés , Javier Del Ser , David Camacho

Multilabel classification is an emergent data mining task with a broad range of real world applications. Learning from imbalanced multilabel data is being deeply studied latterly, and several resampling methods have been proposed in the…

Machine Learning · Computer Science 2018-02-15 Francisco Charte , Antonio J. Rivera , María J. del Jesus , Francisco Herrera

In this paper, a high-speed online neural network classifier based on extreme learning machines for multi-label classification is proposed. In multi-label classification, each of the input data sample belongs to one or more than one of the…

Machine Learning · Computer Science 2016-09-06 Rajasekar Venkatesan , Meng Joo Er , Mihika Dave , Mahardhika Pratama , Shiqian Wu

In multi-label classification, an instance may be associated with a set of labels simultaneously. Recently, the research on multi-label classification has largely shifted its focus to the other end of the spectrum where the number of labels…

Machine Learning · Computer Science 2016-04-06 Li Li , Houfeng Wang

Context: Classification of software requirements into different categories is a critically important task in requirements engineering (RE). Developing machine learning (ML) approaches for requirements classification has attracted great…

Software Engineering · Computer Science 2023-02-27 Manal Binkhonain , Liping Zhao

For protein sequence datasets, unlabeled data has greatly outpaced labeled data due to the high cost of wet-lab characterization. Recent deep-learning approaches to protein prediction have shown that pre-training on unlabeled data can yield…

Machine Learning · Computer Science 2020-12-02 Pascal Sturmfels , Jesse Vig , Ali Madani , Nazneen Fatema Rajani
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