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Optical microscopy has a diffraction limited resolution of about 250 nm. Fluorescence methods (e.g. PALM, STORM, STED) beat this, but they are still limited to 10 s of nm, and the images are an indirect pointillist representation of only…

Reconstructing 3D humans from a single image has been extensively investigated. However, existing approaches often fall short on capturing fine geometry and appearance details, hallucinating occluded parts with plausible details, and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Zhenzhen Weng , Jingyuan Liu , Hao Tan , Zhan Xu , Yang Zhou , Serena Yeung-Levy , Jimei Yang

Coherent Diffraction Imaging (CDI), a technique where an object is reconstructed from a single (2D or 3D) diffraction pattern, recovers the lost diffraction phases without a priori knowledge of the extent (support) of the object, which…

Materials Science · Physics 2020-08-27 Vincent Favre-Nicolin , Steven Leake , Yuriy Chushkin

We analyze multi-bounce propagation of light in an unknown hidden volume and demonstrate that the reflected light contains sufficient information to recover the 3D structure of the hidden scene. We formulate the forward and inverse theory…

We develop an integrated system of holographic optical trapping and multimodal nonlinear microscopy and perform simultaneous three-dimensional optical manipulation and non-invasive structural imaging of composite soft-matter systems. We…

Soft Condensed Matter · Physics 2015-05-20 Rahul P. Trivedi , Taewoo Lee , Kris A. Bertness , Ivan I. Smalyukh

Virtual staining of tissue offers a powerful tool for transforming label-free microscopy images of unstained tissue into equivalents of histochemically stained samples. This study presents a diffusion model-based super-resolution virtual…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Yijie Zhang , Luzhe Huang , Nir Pillar , Yuzhu Li , Hanlong Chen , Aydogan Ozcan

We showed that a 2D depth map representing an incoherent 3D opaque scene is directly encoded in the response function of an imaging optics. As a result, the optics creates an image that depends nonlinearly on the depth map. Furthermore,…

Optics · Physics 2025-08-28 Nan Zhang , Arvin Keshvari , Ata Shakeri , Zin Lin

The 3-dimensional (3D) structure of the genome is of significant importance for many cellular processes. In this paper, we study the problem of reconstructing the 3D structure of chromosomes from Hi-C data of diploid organisms, which poses…

Genomics · Quantitative Biology 2024-05-30 Diego Cifuentes , Jan Draisma , Oskar Henriksson , Annachiara Korchmaros , Kaie Kubjas

High resolution image sensors require electrical access to each individual pixel for signal readout. Such access is especially challenging for ultra-miniaturized pixels, for heterogeneously integrated sensing and readout layers in…

Methods for 3D reconstruction such as Photometric stereo recover the shape and reflectance properties using multiple images of an object taken with variable lighting conditions from a fixed viewpoint. Photometric stereo assumes that a scene…

Computer Vision and Pattern Recognition · Computer Science 2018-11-07 Anish R. Khadka , Paolo Remagnino , Vasileios Argyriou

A simple method of constructing the 3D surface of non-transparent micro-objects by extending the depth-of-field on the whole attainable surface is presented. The series of images of a sample are recorded by the sequential movement of the…

Instrumentation and Detectors · Physics 2009-04-15 V. V. Berejnov

We present a wide-field multi-pass implementation of label-free imaging flow cytometry. Our technique is shown for high-speed flow imaging of ensembles of human red blood cells with up to four passes, demonstrating x4 enhancement in…

Vibrational microscopy provides label-free, bond-selective chemical contrast by detecting molecular vibrations, making it invaluable for biomedical research. While conventional methods rely on the direct detection of Raman scattering or…

Optics · Physics 2025-02-10 Keiichiro Toda , Takuro Ideguchi

In this work, we propose a novel method for continuous real-time measurement of the dynamics of the nonlinear refractive index n2. This is particularly important for characterizing phenomena or materials (such as biological tissues, gases…

We study the problem of novel view synthesis from sparse source observations of a scene comprised of 3D objects. We propose a simple yet effective approach that is neither continuous nor implicit, challenging recent trends on view…

Computer Vision and Pattern Recognition · Computer Science 2021-12-10 Pengsheng Guo , Miguel Angel Bautista , Alex Colburn , Liang Yang , Daniel Ulbricht , Joshua M. Susskind , Qi Shan

In this paper, we present a new compositing approach to obtain stylized reflections and refractions with a simple control. Our approach does not require any mask or separate 3D rendering. Moreover, only one additional image is sufficient to…

Graphics · Computer Science 2024-01-05 Ergun Akleman , Youyou Wang , Ozgur Gonen

Photoacoustic imaging has emerged as a powerful, non-invasive modality for various biomedical applications. Conventional photoacoustic systems require contact-based ultrasound detection and expensive and bulky high-power lasers for the…

Applied Physics · Physics 2025-01-06 Emiel Dieussaert , Roel Baets , Hilde Jans , Xavier Rottenberg , Yanlu Li

A new scheme based on (i) upcoming brilliant X-ray Free Electron Laser (FEL) sources, (ii) novel energy and angular dispersive, large-area electron imagers and (iii) the well-known photoelectron holography is elaborated that provides…

Atomic Physics · Physics 2015-05-14 F. Krasniqi , B. Najjari , L. Strüder , D. Rolles , A. Voitkiv , J. Ullrich

The dynamic architecture of the microtubule cytoskeleton is crucial for cell division, motility and morphogenesis. The dynamic properties of microtubules - growth, shrinkage, nucleation and severing - are regulated by an arsenal of…

Quantitative Methods · Quantitative Biology 2021-07-06 Yin-wei Kuo , Jonathon Howard

We consider a differential method of maximum entropy that is based on the linearity of Fourier transform and involves reconstruction of images from the differences of the visibility function. The efficiency of the method is demonstrated…

Astrophysics · Physics 2015-06-24 Anisa T. Bajkova
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