English
Related papers

Related papers: Ultrametrics in the genetic code and the genome

200 papers

How to represent the genetic code? Despite the fact that it is extensively known, the DNA mapping into proteins remains as one of the relevant discoveries of genetics. However, modern genomic signal processing usually requires converting…

Other Quantitative Biology · Quantitative Biology 2015-03-10 H. M. de Oliveira , N. S. Santos-Magalhaes

We study infinite tree and ultrametric matrices, and their action on the boundary of the tree. For each tree matrix we show the existence of a symmetric random walk associated to it and we study its Green potential. We provide a…

Probability · Mathematics 2007-05-23 Claude Dellacherie , Servet Martinez , Jaime San Martin

An important application of distance geometry to biochemistry studies the embeddings of the vertices of a weighted graph in the three-dimensional Euclidean space such that the edge weights are equal to the Euclidean distances between…

Computational Geometry · Computer Science 2011-03-08 Leo Liberti , Carlile Lavor , Benoit Masson , Antonio Mucherino

Random network coding recently attracts attention as a technique to disseminate information in a network. This paper considers a non-coherent multi-shot network, where the unknown and time-variant network is used several times. In order to…

Information Theory · Computer Science 2016-11-17 Antonia Wachter-Zeh , Markus Stinner , Vladimir Sidorenko

Evolutionary algorithms borrow from biology the concepts of mutation and selection in order to evolve optimized solutions to known problems. The GENETIS collaboration is developing genetic algorithms for designing antennas that are more…

Some aspects of analysis involving fields with absolute value functions are discussed, which includes the real or complex numbers with their standard absolute values, as well as ultrametric situations like the p-adic numbers.

Classical Analysis and ODEs · Mathematics 2015-04-28 Stephen Semmes

Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and…

Machine Learning · Computer Science 2019-12-16 Siddhartha Dhar Choudhury , Shashank Pandey , Kunal Mehrotra

Phylogenetic inference-the derivation of a hypothesis for the common evolutionary history of a group of species- is an active area of research at the intersection of biology, computer science, mathematics, and statistics. One assumes the…

Populations and Evolution · Quantitative Biology 2016-06-21 Ruth Davidson , Joseph Rusinko , Zoe Vernon , Jing Xi

Phylogenetics is now fundamental in life sciences, providing insights into the earliest branches of life and the origins and spread of epidemics. However, finding suitable phylogenies from the vast space of possible trees remains…

Populations and Evolution · Quantitative Biology 2024-01-24 Matthew J Penn , Neil Scheidwasser , Joseph Penn , Christl A Donnelly , David A Duchêne , Samir Bhatt

The tendencies described in this work were revealed in the course of examination of adenine and uracil distribution in the mRNA encoding sequence. The study also discusses the usage of codons occupied by the amino acid arginine in the table…

Other Quantitative Biology · Quantitative Biology 2009-08-11 Denis A. Semenov

We introduce genetic algorithms as a means to estimate the accuracy required to discriminate among different models using experimental observables. We exemplify the technique in the context of the minimal supersymmetric standard model. If…

High Energy Physics - Phenomenology · Physics 2009-11-10 B. C. Allanach , D. Grellscheid , F. Quevedo

The genetic code is the set of rules by which information encoded in genetic material (DNA or RNA sequences) is translated into proteins (amino acid sequences) by living cells. The code defines a mapping between tri-nucleotide sequences,…

Other Quantitative Biology · Quantitative Biology 2015-12-03 Jayanta Kumar Das , Atrayee Majumder , Pabitra Pal Choudhury

We introduce a formalism for the geometry of eukaryotic cells and organisms.Cells are taken to be star-convex with good biological reason. This allows for a convenient description of their extent in space as well as all manner of cell…

Other Quantitative Biology · Quantitative Biology 2014-10-03 Nadya Morozova , Robert Penner

In this paper we consider aspects of geometric observability for hypergraphs, extending our earlier work from the uniform to the nonuniform case. Hypergraphs, a generalization of graphs, allow hyperedges to connect multiple nodes and…

Dynamical Systems · Mathematics 2024-04-12 Joshua Pickard , Cooper Stansbury , Amit Surana , Indika Rajapakse , Anthony Bloch

The genetic code structure into distinct multiplet-classes as well as the numeric degeneracies of the latter are revealed by a two-step process. First, an empirical inventory of the degeneracies (of the shuffled multiplets) in two specific…

Other Quantitative Biology · Quantitative Biology 2009-11-13 Tidjani Negadi

The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical…

Methodology · Statistics 2016-09-29 Marco Scutari , Ian Mackay , David Balding

We investigate the large-scale geometry of the DNA-protein complex of chromatin using a generalized optimality principle, which requires that not only should all sub-parts of a natural process be optimal but also the unfolding of higher…

Biomolecules · Quantitative Biology 2024-02-16 Subhash Kak

The proof of the theorem, which states that the Euclidean metric on the set of random points in an $n$-dimensional Euclidean space with the distribution of a special class, converges in probability in the limit $n\rightarrow\infty$ to the…

Mathematical Physics · Physics 2014-04-22 Alexander P. Zubarev

How robust is the natural genetic code with respect to mistranslation errors? It has long been known that the genetic code is very efficient in limiting the effect of point mutation. A misread codon will commonly code either for the same…

Biological Physics · Physics 2009-11-03 Dimitri Gilis , Serge Massar , Nicolas Cerf , Marianne Rooman

We review the theory and practice of determining what parts of a data set are ultrametric. It is assumed that the data set, to begin with, is endowed with a metric, and we include discussion of how this can be brought about if a…

Artificial Intelligence · Computer Science 2013-09-17 Fionn Murtagh