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The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…
Three-dimensional digital subtraction angiography (3D-DSA) is a widely adopted technique for clinical evaluation of contrast-enhanced vasculatures. The distribution of a contrast agent such as iodine is often estimated via temporal…
Propagation-based X-ray phase-contrast imaging (PBI) enables high-contrast visualization of lung structures and holds strong medical potential. However, safe translation to the clinic will require a substantial radiation dose reduction,…
Computed Tomography (CT) takes X-ray measurements on the subjects to reconstruct tomographic images. As X-ray is radioactive, it is desirable to control the total amount of dose of X-ray for safety concerns. Therefore, we can only select a…
Statistical image reconstruction (SIR) methods have shown potential to substantially improve the image quality of low-dose X-ray computed tomography (CT) as compared to the conventional filtered back-projection (FBP) method for various…
Quantum physics has brought enhanced capability in various sensing applications. Despite challenges from noise and loss in the radio-frequency (RF) domain, [Phys. Rev. Lett. 124, 150502 (2020)] demonstrates a route for enhanced RF-receiver…
X-ray phase-contrast imaging offers enhanced sensitivity for weakly-attenuating materials, such as breast and brain tissue, but has yet to be widely implemented clinically due to high coherence requirements and expensive x-ray optics.…
Convolutional Neural Networks (CNN) based image reconstruction methods have been intensely used for X-ray computed tomography (CT) reconstruction applications. Despite great success, good performance of this data-based approach critically…
Scanning transmission electron microscopy (STEM) has been extensively used for imaging complex materials down to atomic resolution. The most commonly employed STEM modality, annular dark-field imaging, produces easily-interpretable…
Contrast-enhanced computed tomography (CECT) is pivotal for highlighting tissue perfusion and vascularity, yet its clinical ubiquity is impeded by the invasive nature of contrast agents and radiation risks. While virtual contrast…
In this paper, we investigate image reconstruction for dynamic Computed Tomography. The motion of the target with respect to the measurement acquisition rate leads to highly resolved in time but highly undersampled in space measurements.…
Blur in X-ray radiographs not only reduces the sharpness of image edges but also reduces the overall contrast. The effective blur in a radiograph is the combined effect of blur from multiple sources such as the detector panel, X-ray source…
With substantial public concerns on potential cancer risks and health hazards caused by the accumulated radiation exposure in medical imaging, reducing radiation dose in X-ray based medical imaging such as Computed Tomography Perfusion…
In recent years, accelerated MRI reconstruction based on deep learning has led to significant improvements in image quality with impressive results for high acceleration factors. However, from a clinical perspective image quality is only…
X-ray microtomography at synchrotron sources is fundamentally limited by the high radiation dose applied to the samples, which restricts investigations to non-native tissue states and thereby compromises the biological relevance of the…
Multi-contrast MRI sequences allow for the acquisition of images with varying tissue contrast within a single scan. The resulting multi-contrast images can be used to extract quantitative information on tissue microstructure. To make such…
This paper presents a new approach for contrast enhancement of spinal cord medical images based on multirate scheme incorporated into multiscale retinex algorithm. The proposed work here uses HSV color space, since HSV color space separates…
X-ray fluorescence computed tomography (XFCT) and K-edge computed tomography (CT) are two important modalities to quantify a distribution of gold nanoparticles (GNPs) in a small animal for preclinical studies. It is valuable to determine…
CEST has proven to be a valuable technique for the detection of hyperpolarized xenon-based functionalized contrast agents. Additional information can be encoded in the spectral dimension, allowing the simultaneous detection of multiple…
Quantitative differential phase contrast imaging of materials in atomic-resolution scanning transmission electron microscopy using segmented detectors is limited by various factors, including coherent and incoherent aberrations, detector…