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A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optimal sequential testing theory. These designs are easy to…

Statistics Theory · Mathematics 2011-05-25 Jay Bartroff , Tze Leung Lai

A brief review of the search for variation of the fine structure constant in quasar absorption spectra is presented. Special consideration is given to the role of atomic calculations in the analysis of the observed data. A range of methods…

Atomic Physics · Physics 2015-05-13 V. A. Dzuba , V. V. Flambaum

To resolve the non-convex optimization problem in partial wave analysis, this paper introduces a novel approach that incorporates fraction constraints into the likelihood function. This method offers significant improvements in both the…

High Energy Physics - Experiment · Physics 2024-01-22 Xiang Dong , Chu-Cheng Pan , Yu-Chang Sun , Ao-Yan Cheng , Ao-Bo Wang , Hao Cai , Kai Zhu

Firth-type logistic regression has become a standard approach for the analysis of binary outcomes with small samples. Whereas it reduces the bias in maximum likelihood estimates of coefficients, bias towards 1/2 is introduced in the…

Methodology · Statistics 2021-01-20 Rainer Puhr , Georg Heinze , Mariana Nold , Lara Lusa , Angelika Geroldinger

This paper is concerned with particle filtering for $\alpha$-stable stochastic volatility models. The $\alpha$-stable distribution provides a flexible framework for modeling asymmetry and heavy tails, which is useful when modeling financial…

Computation · Statistics 2014-05-20 Emilian Vankov , Katherine B. Ensor

In recent years, there have been many practical applications of anomaly detection such as in predictive maintenance, detection of credit fraud, network intrusion, and system failure. The goal of anomaly detection is to identify in the test…

Applications · Statistics 2020-06-12 Zekun Xu , Deovrat Kakde , Arin Chaudhuri

The dynamical likelihood method for analysis of high energy collider events is reformulated. The method is to reconstruct the elementary parton state from observed quantities. The basic assumption is that each of final state partons…

High Energy Physics - Experiment · Physics 2007-05-23 Kunitaka Kondo

In this paper, we study a functional regression setting where the random response curve is unobserved, and only its dichotomized version observed at a sequence of correlated binary data is available. We propose a practical computational…

Methodology · Statistics 2020-12-07 Fatemeh Asgari , Mohammad Hossein Alamatsaz , Valeria Vitelli , Saeed Hayati

Automatic differentiation (AD) has driven recent advances in machine learning, including deep neural networks and Hamiltonian Markov Chain Monte Carlo methods. Partially observed nonlinear stochastic dynamical systems have proved resistant…

Methodology · Statistics 2024-07-04 Kevin Tan , Giles Hooker , Edward L. Ionides

Simulation models of complex dynamics in the natural and social sciences commonly lack a tractable likelihood function, rendering traditional likelihood-based statistical inference impossible. Recent advances in machine learning have…

Machine Learning · Statistics 2022-02-24 Joel Dyer , Patrick Cannon , Sebastian M Schmon

This paper discusses some features of the spectral line profile theory used in the treatment of measured atomic transitions. It is shown that going beyond the established linear approximation for the spectral line contour in the case of its…

Atomic Physics · Physics 2024-05-03 D. Solovyev , A. Anikin , T. Zalialiutdinov

Covariate adjustment is an important tool in the analysis of randomized clinical trials and observational studies. It can be used to increase efficiency and thus power, and to reduce possible bias. While most statistical tests in randomized…

Methodology · Statistics 2011-08-03 Xiaoru Wu , Zhiliang Ying

Modern data analysis frequently involves variables with highly non-Gaussian marginal distributions. However, commonly used analysis methods are most effective with roughly Gaussian data. This paper introduces an automatic transformation…

Methodology · Statistics 2016-01-11 Qing Feng , Jan Hannig , J. S. Marron

In this paper we obtain an adjusted version of the likelihood ratio test for errors-in-variables multivariate linear regression models. The error terms are allowed to follow a multivariate distribution in the class of the elliptical…

Statistics Theory · Mathematics 2011-08-05 Tatiane F. N. Melo , Silvia L. P. Ferrari

Predictions of nuclear properties far from measured data are inherently imprecise because of uncertainties in our knowledge of nuclear forces and in our treatment of quantum many-body effects in strongly-interacting systems. While the model…

Nuclear Theory · Physics 2022-09-14 Rodrigo Navarro Perez , Nicolas Schunck

The study presents a novel approach for stochastic nonlinear model updating in structural dynamics, employing a Bayesian framework integrated with Markov Chain Monte Carlo (MCMC) sampling for parameter estimation by using an approximated…

In this work, the calculation of complexity on atomic systems is considered. In order to unveil the increasing of this statistical magnitude with the atomic number due to the relativistic effects, recently reported in [A. Borgoo, F. De…

Chaotic Dynamics · Physics 2008-06-12 Jaime Sanudo , Ricardo Lopez-Ruiz

In this paper we consider a statistical estimation problem known as atomic deconvolution. Introduced in reliability, this model has a direct application when considering biological data produced by flow cytometers. In these experiments,…

Statistics Theory · Mathematics 2017-10-12 Manon Costa , Sébastien Gadat , Pauline Gonnord , Laurent Risser

Parameterized optimization and parameter estimation is of great importance in almost every branch of modern science, technology and engineering. A practical issue in the problem is that when the parameter space is large and the available…

General Relativity and Quantum Cosmology · Physics 2014-02-26 Yan Wang

Measuring the F\"{o}rster resonance energy transfer (FRET) efficiency of freely diffusing single molecules provides information about the sampled conformational states of the molecules. Under equilibrium conditions, the distribution of the…

Biological Physics · Physics 2020-08-28 Marijn de Boer
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