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A common analytical problem in neuroscience is the interpretation of neural activity with respect to sensory input or behavioral output. This is typically achieved by regressing measured neural activity against known stimuli or behavioral…

Computation · Statistics 2016-06-28 Kamiar Rahnama Rad , Timothy A. Machado , Liam Paninski

Robust characterization of dynamic causal interactions in multivariate biomedical signals is essential for advancing computational and algorithmic methods in biomedical imaging. Conventional approaches, such as Dynamic Bayesian Networks…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Farwa Abbas , Wei Dai , Zoran Cvetkovic , Verity McClelland

We propose a multivariate GARCH model for non-stationary health time series by modifying the variance of the observations of the standard state space model. The proposed model provides an intuitive way of dealing with heteroskedastic data…

Methodology · Statistics 2023-03-16 Zayd Omar , David A. Stephens , Alexandra M. Schmidt , David L. Buckeridge

The recent availability of huge, many-dimensional data sets, like those arising from genome-wide association studies (GWAS), provides many opportunities for strengthening causal inference. One popular approach is to utilize these…

Machine Learning · Statistics 2020-12-21 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

Characterising cause-effect relationships in complex systems is fundamental to understanding their underlying mechanisms. Granger causality (GC) remains a widely used computational tool for identifying causal relationships in time series…

Machine Learning · Statistics 2026-05-26 S. A. Adedayo

This paper focuses on the Bayesian Network Propensity Score (BNPS), a novel approach for estimating treatment effects in observational studies characterized by unknown (and likely unbalanced) designs and complex dependency structures among…

Granger causal modeling is an emerging topic that can uncover Granger causal relationship behind multivariate time series data. In many real-world systems, it is common to encounter a large amount of multivariate time series data collected…

Machine Learning · Computer Science 2021-02-11 Yunfei Chu , Xiaowei Wang , Jianxin Ma , Kunyang Jia , Jingren Zhou , Hongxia Yang

Our goal is to model and measure functional and effective (directional) connectivity in multichannel brain physiological signals (e.g., electroencephalograms, local field potentials). The difficulties from analyzing these data mainly come…

Applications · Statistics 2017-12-04 Lechuan Hu , Norbert Fortin , Hernando Ombao

We develop the methodology and a detailed case study in use of a class of Bayesian predictive synthesis (BPS) models for multivariate time series forecasting. This extends the recently introduced foundational framework of BPS to the…

Methodology · Statistics 2022-06-07 Kenichiro McAlinn , Knut Are Aastveit , Jouchi Nakajima , Mike West

Modern health care systems are conducting continuous, automated surveillance of the electronic medical record (EMR) to identify adverse events with increasing frequency; however, many events such as sepsis do not have elucidated prodromes…

Applications · Statistics 2023-05-24 Song Wei , Yao Xie , Christopher S. Josef , Rishikesan Kamaleswaran

Comparative meta-analyses of groups of subjects by integrating multiple observational studies rely on estimated propensity scores (PSs) to mitigate covariate imbalances. However, PS estimation grapples with the theoretical and practical…

Methodology · Statistics 2024-05-09 Subharup Guha , Yi Li

Network data are increasingly collected along with other variables of interest. Our motivation is drawn from neurophysiology studies measuring brain connectivity networks for a sample of individuals along with their membership to a low or…

Methodology · Statistics 2018-09-11 Daniele Durante , David B. Dunson

Background: The most widely used approach to joint modelling of repeated measurement and time to event data is to combine a linear Gaussian random effects model for the repeated measurements with a log-Gaussian frailty model for the…

Methodology · Statistics 2016-09-12 Elisabeth Waldmann , David Taylor-Robinson

In recent years, Bayesian statistics methods in neuroscience have been showing important advances. In particular, detection of brain signals for studying the complexity of the brain is an active area of research. Functional magnetic…

Methodology · Statistics 2017-06-06 Jairo Alberto Fuquene Patiño , Brenda Betancourt , João B. M. Pereira

Electroencephalograms (EEG) are noninvasive measurement signals of electrical neuronal activity in the brain. One of the current major statistical challenges is formally measuring functional dependency between those complex signals. This…

Methodology · Statistics 2021-05-14 Marco Antonio Pinto-Orellana , Peyman Mirtaheri , Hugo L. Hammer , Hernando Ombao

Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…

We investigate the state space reconstruction from multiple time series derived from continuous and discrete systems and propose a method for building embedding vectors progressively using information measure criteria regarding past,…

Chaotic Dynamics · Physics 2015-05-19 Ioannis Vlachos , Dimitris Kugiumtzis

We develop an efficient sampling approach for handling complex missing data patterns and a large number of missing observations in conditionally Gaussian state space models. Two important examples are dynamic factor models with unbalanced…

Econometrics · Economics 2023-02-08 Joshua C. C. Chan , Aubrey Poon , Dan Zhu

The estimation from available data of parameters governing epidemics is a major challenge. In addition to usual issues (data often incomplete and noisy), epidemics of the same nature may be observed in several places or over different…

Methodology · Statistics 2021-09-20 Romain Narci , Maud Delattre , Catherine Larédo , Elisabeta Vergu

Granger causality is a statistical notion of causal influence based on prediction via vector autoregression. Developed originally in the field of econometrics, it has since found application in a broader arena, particularly in neuroscience.…

Mathematical Physics · Physics 2015-05-14 Lionel Barnett , Adam B Barrett , Anil K. Seth