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The concept of feature selectivity in sensory signal processing can be formalized as dimensionality reduction: in a stimulus space of very high dimensions, neurons respond only to variations within some smaller, relevant subspace. But if…

Neurons and Cognition · Quantitative Biology 2016-03-15 Kanaka Rajan , William Bialek

A comprehensive study of the coded performance of long-haul spectrally-efficient WDM optical fiber transmission systems with different coded modulation decoding structures is presented. Achievable information rates are derived for three…

Information Theory · Computer Science 2024-01-25 Gabriele Liga , Alex Alvarado , Erik Agrell , Polina Bayvel

One strategy to scale up ML-driven science is to increase wet lab experiments' information density. We present a method based on a neural extension of compressed sensing to function space. We measure the activity of multiple different…

Living cells communicate information about physiological conditions by producing signaling molecules in a specific timed manner. Different conditions can result in the same total amount of a signaling molecule, differing only in the pattern…

Molecular Networks · Quantitative Biology 2018-10-09 Jackson O'Brien , Arvind Murugan

This paper focuses on molecular communication (MC) systems where the signaling molecules may participate in a reversible bimolecular reaction in the channel. The motivation for studying these MC systems is that they can realize the concept…

Information Theory · Computer Science 2017-11-02 Vahid Jamali , Nariman Farsad , Robert Schober , Andrea Goldsmith

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

Biological organisms are composed of numerous interconnected biochemical processes. Diseases occur when normal functionality of these processes is disrupted. Thus, understanding these biochemical processes and their interrelationships is a…

Artificial Intelligence · Computer Science 2014-03-04 Saadat Anwar

This paper explores the integration of deep learning techniques for joint sensing and communications, with an extension to semantic communications. The integrated system comprises a transmitter and receiver operating over a wireless…

Networking and Internet Architecture · Computer Science 2024-10-22 Yalin E. Sagduyu , Tugba Erpek , Aylin Yener , Sennur Ulukus

Stochastic models of biochemical reaction networks are widely used to capture intrinsic noise in cellular systems. The typical formulation of these models are based on Markov processes for which there is extensive research on efficient…

Molecular Networks · Quantitative Biology 2025-12-03 Thomas P. Steele , David J. Warne

Time-resolved single-molecule biophysical experiments yield data that contain a wealth of dynamic information, in addition to the equilibrium distributions derived from histograms of the time series. In typical force spectroscopic setups…

Biomolecules · Quantitative Biology 2011-07-14 Michael Hinczewski , Yann von Hansen , Roland R. Netz

Transcriptomic data is a treasure-trove in modern molecular biology, as it offers a comprehensive viewpoint into the intricate nuances of gene expression dynamics underlying biological systems. This genetic information must be utilised to…

Molecular Networks · Quantitative Biology 2023-12-13 Vikram Singh , Vikram Singh

A real-time communication system with two encoders communicating with a single receiver over separate noisy channels is considered. The two encoders make distinct partial observations of a Markov source. Each encoder must encode its…

Information Theory · Computer Science 2009-10-27 Ashutosh Nayyar , Demosthenis Teneketzis

Large information sizes in samples and features can be encoded to speed up the learning of statistical models based on linear algebra and remove unwanted signals. Encoding information can reduce both sample and feature dimension to a…

Machine Learning · Computer Science 2022-06-23 David Banh , Alan Huang

Data for several applications in diverse fields can be represented as multiple matrices that are linked across rows or columns. This is particularly common in molecular biomedical research, in which multiple molecular "omics" technologies…

Machine Learning · Statistics 2024-08-02 Eric F. Lock

Molecular Communication as the most potential methods to solve the communication in nano scale, for it's derived from nature, and it becomes more and more prevalent. Though molecular communication happens in three dimensional situation,…

Emerging Technologies · Computer Science 2016-03-14 Pengfei Lu , Zhenqiang Wu

We introduce a model for describing the dynamics of large numbers of interacting cells. The fundamental dynamical variables in the model are sub-cellular elements, which interact with each other through phenomenological intra- and…

Quantitative Methods · Quantitative Biology 2007-05-23 T. J. Newman

Diffusive molecular communications (DiMC) have recently gained attention as a candidate for nano- to micro- and macro-scale communications due to its simplicity and energy efficiency. As signal propagation is solely enabled by Brownian…

Information Theory · Computer Science 2021-01-11 Mustafa Can Gursoy , Masoumeh Nasiri-Kenari , Urbashi Mitra

Integrating different molecular layers, i.e., multiomics data, is crucial for unraveling the complexity of diseases; yet, most deep generative models either prioritize predictive performance at the expense of interpretability or enforce…

Machine Learning · Computer Science 2025-11-06 Mihriban Kocak Balik , Pekka Marttinen , Negar Safinianaini

Two-dimensional electronic spectroscopy (2DES) has enabled significant discoveries in both biological and synthetic energy-transducing systems. Although deriving chemical information from 2DES is a complex task, machine learning (ML) offers…

Chemical Physics · Physics 2025-03-21 Jonathan D. Schultz , Kelsey A. Parker , Bashir Sbaiti , David N. Beratan

Inter and intra-cellular signaling are essential for individual cells to execute various physiological tasks and accurately respond to changes in their environment. Signaling is carried out via diffusible molecules, the transport of which…

Soft Condensed Matter · Physics 2020-10-13 Sumantra Sarkar , Sandeep Choubey