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The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Jun Wang , Yang Zhao , Linglong Qian , Xiaohan Yu , Yongsheng Gao

Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker

Modern biomedical image analysis using deep learning often encounters the challenge of limited annotated data. To overcome this issue, deep generative models can be employed to synthesize realistic biomedical images. In this regard, we…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Yuli Wu , Weidong He , Dennis Eschweiler , Ningxin Dou , Zixin Fan , Shengli Mi , Peter Walter , Johannes Stegmaier

Optical coherence tomography angiography (OCTA) is an imaging technique that allows for non-invasive investigation of the microvasculature in the retina. OCTA uses laser light reflectance to measure moving blood cells. Hereby, it visualizes…

Tissues and Organs · Quantitative Biology 2020-02-11 Astrid M. E. Engberg , Vedrana A. Dahl , Anders B. Dahl

Segmenting of clinically important retinal blood vessels into arteries and veins is a prerequisite for retinal vessel analysis. Such analysis can provide potential insights and bio-markers for identifying and diagnosing various retinal eye…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sharan SK , Subin Sahayam , Umarani Jayaraman , Lakshmi Priya A

Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…

Medical Physics · Physics 2023-07-24 Xueshen Li , Zhenxing Dong , Hongshan Liu , Jennifer J. Kang-Mieler , Yuye Ling , Yu Gan

Quantification of intra-retinal boundaries in optical coherence tomography (OCT) is a crucial task for studying and diagnosing neurological and ocular diseases. Since manual segmentation of layers is usually a time consuming task and relay…

Computer Vision and Pattern Recognition · Computer Science 2015-02-17 Mahdi Salarian

Accurate retinal vessel segmentation is a challenging problem in color fundus image analysis. An automatic retinal vessel segmentation system can effectively facilitate clinical diagnosis and ophthalmological research. Technically, this…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Muyi Sun , Guanhong Zhang

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Optical Coherence Tomography (OCT) is a widely used non-invasive biomedical imaging modality that can rapidly provide volumetric images of samples. Here, we present a deep learning-based image reconstruction framework that can generate…

Image and Video Processing · Electrical Eng. & Systems 2021-07-30 Yijie Zhang , Tairan Liu , Manmohan Singh , Yilin Luo , Yair Rivenson , Kirill V. Larin , Aydogan Ozcan

This study introduces a groundbreaking optical coherence tomography (OCT) imaging system dedicated for high-throughput screening applications using ex vivo tissue culture. Leveraging OCT's non-invasive, high-resolution capabilities, the…

Diabetic retinopathy is the most important complication of diabetes. Early diagnosis of retinal lesions helps to avoid visual loss or blindness. Due to high-resolution and small-size lesion regions, applying existing methods, such as…

Computer Vision and Pattern Recognition · Computer Science 2019-01-21 Zizheng Yan , Xiaoguang Han , Changmiao Wang , Yuda Qiu , Zixiang Xiong , Shuguang Cui

With the introduction of spectral-domain optical coherence tomography (OCT), much larger image datasets are routinely acquired compared to what was possible using the previous generation of time-domain OCT. Thus, the need for 3-D…

Computer Vision and Pattern Recognition · Computer Science 2012-05-03 Yankui Sun , Tian Zhang

This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Manoj S H , Arya A Bosale

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

Inverse scattering in optical coherence tomography (OCT) seeks to recover both structural images and intrinsic tissue optical properties, including refractive index, scattering coefficient, and anisotropy. This inverse problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Jinglun Yu , Yaning Wang , Wenhan Guo , Yuan Gao , Yu Sun , Jin U. Kang

In this paper, we propose a novel retinal layer boundary model for segmentation of optical coherence tomography (OCT) images. The retinal layer boundary model consists of 9 open parametric contours representing the 9 retinal layers in OCT…

Computer Vision and Pattern Recognition · Computer Science 2018-08-10 Jinming Duan , Weicheng Xie , Ryan Wen Liu , Christopher Tench , Irene Gottlob , Frank Proudlock , Li Bai

Segmentation of retinal vessel images is critical to the diagnosis of retinopathy. Recently, convolutional neural networks have shown significant ability to extract the blood vessel structure. However, it remains challenging to refined…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Geng-Xin Xu , Chuan-Xian Ren

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

3D to 2D retinal vessel segmentation is a challenging problem in Optical Coherence Tomography Angiography (OCTA) images. Accurate retinal vessel segmentation is important for the diagnosis and prevention of ophthalmic diseases. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-17 Zhuojie Wu , Zijian Wang , Wenxuan Zou , Fan Ji , Hao Dang , Wanting Zhou , Muyi Sun
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