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Soft valves serve to modulate and rectify flows in complex vasculatures across the tree of life, e.g. in the heart of every human reading this. Here we consider a minimal physical model of the heart mitral valve modeled as a flexible…
Double-wall cylindrical shells are widely used in applications where resistance to acoustic shock loading is critical. While the transient vibroacoustic behavior of single-walled shells has been extensively investigated, extending these…
Accurate segmentation of the Left Ventricle (LV) holds substantial importance due to its implications in disease detection, regional analysis, and the development of complex models for cardiac surgical planning. CMR is a golden standard for…
Two-dimensional representation of 3D anatomical structures is a simple and intuitive way for analysing patient information across populations and image modalities. It also allows convenient visualizations that can be included in clinical…
Background. Studies have shown that the conventional left ventricular mechanical dyssynchrony (LVMD) parameters have their own statistical limitations. The purpose of this study is to extract new LVMD parameters from the phase analysis of…
Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies, and ischaemic heart disease. However, methods to detect…
Patients with hypoplastic left heart syndrome (HLHS) are born with an underdeveloped left heart. They typically receive a sequence of surgeries that result in a single ventricle physiology called the Fontan circulation. While these patients…
This paper proposes an approach combining the Volume Penalization (VP) and the the Lattice Boltzmann method (LBM) to compute fluid structure interaction involving rigid bodies. The method consists in adding a force term in the LBM…
The segmentation of the left ventricle (LV) from CINE MRI images is essential to infer important clinical parameters. Typically, machine learning algorithms for automated LV segmentation use annotated contours from only two cardiac phases,…
Mechano-electric feedbacks (MEFs), which model how mechanical stimuli are transduced into electrical signals, have received sparse investigation by considering electromechanical simulations in simplified scenarios. In this paper, we study…
There are more than 300,000 heart valves implanted annually worldwide with about 50% of them being mechanical valves. The heart valve replacement is often a common treatment for severe valvular disease. However, valves may dysfunction…
Mechanical heart valve replacement is the preferred alternative in younger patients with severe symptomatic aortic valve disease. However, thrombus and pannus formations are common complications associated with bileaflet mechanical heart…
A major challenge in the computational fluid dynamics modeling of the heart function is the simulation of isovolumetric phases when the hemodynamics problem is driven by a prescribed boundary displacement. During such phases, both…
Acoustic signals are crucial for health monitoring, particularly heart sounds which provide essential data like heart rate and detect cardiac anomalies such as murmurs. This study utilizes a publicly available phonocardiogram (PCG) dataset…
The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical…
Multi-modality cardiac imaging plays a key role in the management of patients with cardiovascular diseases. It allows a combination of complementary anatomical, morphological and functional information, increases diagnosis accuracy, and…
Automatic segmentation of the left ventricle (LV) in late gadolinium enhanced (LGE) cardiac MR (CMR) images is difficult due to the intensity heterogeneity arising from accumulation of contrast agent in infarcted myocardium. In this paper,…
Cardiac re-entry regime of self-organised abnormal synchronisation underlie dangerous arrhythmias and fatal fibrillation. Recent advances in the theory of dissipative vortices, experimental studies, and anatomically realistic computer…
This paper aims at mathematically modeling a new multi-physics conductivity imaging system incorporating mechanical vibrations simultaneously applied to an imaging object together with current injections. We perturb the internal…
This paper presents a numerical method for the simulation of multiscale materials composed of an elastic matrix and slender active inclusions. The setting is motivated by the modeling of vascularized tissues and by problems arising in the…